English Abstract In a porspective prevalence and incidence survey in The
Netherlands in 1999 antimicrobial susceptibility data on invasive
Streptococcus pneumoniae and Staphylococcus aureus infections were collected
sithin the framework of European Antomicrobial Resistance Surveillance
System (EARSS). The EARSS project covered approximately 40% of the Dutch
population (extramural) and 40% of the total number of patient-days
(intramural). Penicillin resistance in S. pneumoniae was minimal; only 9
of 767 (1,2%) isolates were non-susceptible. Resistance to oxacillin in S.
aureus was low, only (0,3%) isolates were MRSA (mecA positive). The
incidence of invasive S. pneumoniae was 117 cases/1.000.000 person-years;
the incidence of invasive penicillin non-susceptible S. pneumoniae was 1
case/1.000.000 person-years. The incidence of invasive S. aureus
infections was 0.25 cases/1000 patient-days; the incidence of invasive
MRSA infections was 0.0006 cases/1000 patient-days. It may be concluded
that resistance to antibiotics in these two pathogens, when compared to
other European countries, is still very low.
Rapport in het kort
Gevoeligheid voor antimicrobiele middelen in
Streptococcus pneumoniae en Staphylococcus aureus werd bepaald in 1999 in
Nederland binnen het raamwerk van het European antomicrobial Resistance
Surveillance System (EARSS). Het EARSS project had in Nederland een
dekkingsgraad van 40% van de Nederlandse populatie (extramuraal) en 40% van
het totale aantal patientdagen (intramuraal). Resistentiie tegen
penicilline in S. pneumoniae was minimaal; slechts 9 van 767 (1,2%) isolatn
waren niet gevoelig. Resistentie tegen oxacilline in S. aureus was ook
laag; slechts 4 ((0,3%) isolaten waren MRSA. de incidentie van invasieve
S. pneumoniae was 117 gevallen/1.000.000 persoonsjaren, de incidentie van
invasieve penicilline niet gevoelige S. pneumoniae was 1 geval/1.000.000
persoonsjaren. De incidentie van invasieve S. aureus infecties was 0,25
gevallen/1000 patientdagen; de incidentie van invasieve MRSA infecties was
0,0006 gevallen/1000 patientdagen. hetis duidelijkj dat resistentie tegen
antibiotica bij deze twee pathogenen in vergelijkijng tot andere Europese
landen nog steeds erg laag is.
