[Toxicokinetics of Polychlorinated-Dibenzo-P-Dioxins and -Furans (PCDD/F's) in Sheep and Lambs.]
Toxicokinetiek van polychloor-dibenzo-p-dioxinen en -furanen (PCDD/F's) in schapen en lammeren
Olling M , Berende PLM , Derks HJGM , Everts H , Jong APJM de , Liem AKD
RIVM Report 643810002
In this report the results of a toxicokinetic study of dioxins and furans in sheep and the transfer of these compounds from ewes to their lambs are given. Pregnant sheep were fed concentrate spiked with a mixture of PCDD/Fs (130 ng I-TEQ/animal/day) for eight consecutive days. To one group of the sheep the bete-agonist Clenbuterol was administered for eight weeks after delivery to influence the fat metabolism. Dioxins and furans were measured in fat and milk samples of the ewes and in their lambs at several time points after delivery.