ETX 2.0. A Program to Calculate Hazardous Concentrations and Fraction Affected, Based on Normally Distributed Toxicity Data
ETX 2.0. Een programma om "hazardous concentrations" en "fraction affected" te berekenen, gebaseerd op normaal verdeelde toxiciteitsgegevens.
26 May 2012, PDF |
68 pages |
van Vlaardingen PLA, Traas TP, Wintersen AM, Aldenberg T
RIVM Report 601501028
This report was written as a manual for the software program, ETX 2.0. The calculation techniques offered here are currently in use in the RIVM project, 'Setting (inter)national environmental quality criteria' (INS), and the EU risk assessment for existing substances. Environmental risk limits for chemical substances are derived here. Both the INS and EU frameworks allow for statistical extrapolation in the presence of sufficient toxicity data, which serves as a basis for an environmental risk limit (INS) or a predicted no-effect concentration (EU existing substances) of a chemical substance. A statistical technique for achieving this result, recently described in the scientific literature, is made accessible to those working on risk assessment and/or standard-setting through the ETX 2.0 program. A CD-ROM is delivered along with the report.