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PIENTER 2-project: second research project on the protection against infectious diseases offered by the national immunization programme in the Netherlands

PIENTER 2-project: tweede onderzoek naar de bescherming tegen infectieziekten waartegen in het Rijksvaccinatieprogramma wordt ingeent

Synopsis

In 2006 and 2007 the RIVM carried out the second PIENTER-study by order of the Ministry of Health, Welfare and Sports (VWS). PIENTER is a Dutch acronym for: Peiling Immunisatie Effect Nederland Ter Evaluatie van het Rijksvaccinatieprogramma. The aim of this study is to gain insight into how well the Dutch population is protected against vaccine-preventable diseases through the national immunization programme (NIP). The results will enable further improvements of the immunization programme to be made as well as identifying those population groups who are less protected. This report describes the design of the study and provides background information on the participants. The people who took part were between 0-79 years old and lived scattered throughout the Netherlands. They completed a questionnaire on their personal details, their state of health and any diseases they have had in the past. In addition, blood samples were taken from the participants to determine the antibody levels of the diseases covered by the programme. Finally, they were asked which vaccinations they have already had. An extra group of non-Western migrants and a group of orthodox-reformed individuals, who refuse vaccination on religious grounds, were also invited to participate. The study provides insight into disease protection levels that were obtained either through vaccination or because a person has had the disease itself. It also provides information on the spread of infectious diseases. In total, 24,147 people were invited to take part in the study. Thirty-three percent of those asked, agreed to participate. Currently, blood samples are available from 7,904 people that will be tested for the presence of antibodies against all of the infectious diseases covered by the programme as well as other infectious diseases. The blood results and questionnaire information will be compared with the results of the first PIENTER-study, which was performed ten years ago. The data will be reported separately.
 

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