de Jong WH, Delmaar C, Gosens I, Nijkamp M, Quik JTK, Vandebriel RJ, van Kesteren PCE, Visser MJ, Park MVDZ, Wijnhoven SWP
RIVM Report 2015-0157
Nanomaterials consisting of particles smaller than 0.1µm are increasingly used in consumer products including cosmetics. Both regulators and manufacturers need to evaluate and manage consumer health risks that may be posed by the use of nanomaterials in cosmetics. This risk assessment is important as the outcome of the risk assessment indicates whether measures need to be taken to mitigate and/or reduce the observed risks.
This report describes the content of an electronic tool (computer program) that can be used for a risk assessment. The NanoCosmetics tool needs to cover all aspects of the risk assessment. So, the tool needs to contain the following components: the physicochemical characterization of the nanomaterials, the estimation of the consumer exposure, the possible hazards (toxicity) induced by the nanomaterials, and finally the risk assessment itself. In cases where only limited information is available, the tool will use default values as input data for the risk assessment. These default values will generally result in a conservative outcome. The overall outcome will be an estimation of potential risk indicating whether specific measures for risk mitigation and/or reduction need to be implemented.
The conclusion of the report is that it is feasible to develop an electronic tool (program) that allows an estimation of the risk of the use of nanomaterials as cosmetic ingredients.