18173 resultaten voor ‘’

  • LICARA NanoScan

    08 september 2017

    The main goal of LICARA is to develop a structured life cycle approach for nanomaterials which enables the evaluation of the benefits and risks qualitatively with low and manageable efforts, over the

  • MARINA Risk Assessment Strategy

    08 september 2017

    A RA strategy is being developed that considers the impact of the varying properties of an NP during various life cycle stages on human health and combined with environmental risks. Within MARINA a two-phase risk assessment strategy has been developed. In Phase 1 (Problem framing) a base set of information is considered, relevant exposure scenarios (RESs) are identified and the scope for Phase 2 (Risk assessment) is established. The relevance of an RES is indicated by information on exposure, fate/kinetics and/or hazard; these three domains are included as separate pillars that contain specific tools. Phase 2 consists of an iterative process of risk characterization, identification of data needs and integrated collection and evaluation of data on the three domains, until sufficient information is obtained to conclude on possible risks in a RES. Only data are generated that are considered to be needed for the purpose of risk assessment. A fourth pillar, risk characterization, is defined and it contains risk assessment tools. This strategy describes a flexible and efficient approach for data collection and risk assessment which is essential to ensure safety of NPs.

  • Control Banding Nanotool

    08 september 2017

    To assess risks associated with nanotechnology operations. The tool estimates an emission probability and severity band and provides advice on what engineering controls to use. It includes nine domains covering handling of liquids, powders and abrasion of solids. Combines hazard “severity” scores and exposure “probability” scores in a matrix to obtain a level of risk and associated controls out of 4 possible levels of increasing risk and associated controls. Control banding (CB) strategies (a qualitative risk characterization and management strategy) offer simplified solutions for controlling worker exposures to constituents that are found in the workplace in the absence of firm toxicological and exposure data.

  • Stoffenmanager Nano

    08 september 2017

    Web-based Control Banding Tool using an Exposure Process Model. To assess health risks qualitatively after exposure to synthetic NPs. It concerns single particles as well as agglomerates or aggregates and applies to NPs that meet all of the following criteria:
    i) particles are not (water) soluble;
    ii) particles are synthetically produced and not released as unintentional by-product of e.g. incomplete combustion processes;
    iii) the size of the primary particles is smaller than 100 nm and/or the specific surface area of the nanopowder is larger than 60 m2/g

  • LICARA NanoScan

    08 september 2017

    The main goal of LICARA is to develop a structured life cycle approach for nanomaterials which enables the evaluation of the benefits and risks qualitatively with low and manageable efforts, over the nanoproduct's life time. It further allows a comparison with the risks and benefits of the conventional (non-nano) poducts. The tool stimulates economic, environmental and social opportunities. This tool is specifically intended for use by SME's to support them in communicating with regulators, and potential clients and investors.

  • NanoRiskCat: A Conceptual Decision Support Tool for Nanomaterials

    08 september 2017

    Screening tool for evaluation of exposure and hazard of NPs contained in products for professional and private use. To categorize and rank the possible exposure and hazards associated with a nanomaterial in a product. The primary focus was on nanomaterials relevant for professional end-users and consumers as well as nanomaterials released into the environment.

  • The Swiss precautionary matrix for synthetic nanomaterials

    08 september 2017

    Allows to estimate 'nanospecific risk potentials' for synthetic nanomaterials and applications for workers, consumers and environment. It also provides the basis for early decision-making for or against new projects.

  • NanoFASE: SimpleBox4Nano screening fate assessment model

    08 september 2017

    Designed originally as a research tool, SimpleBox4Nano has proven most useful in dedicated environmental fate studies, focused at understanding and predicting environmental fate from fundamental physical and chemical substance properties. Screening-level quantitative model, expresses NP transport and concentrations in and across air, rain, surface waters, soil, and sediment, accounting for nano-specific processes such as aggregation, attachment, and dissolution. The SimpleBox4Nano is a nanomaterial-specific developent of the SimpleBox model, which underpins the EU's chemical risk and safety decision-support tool EUSES. SimpleBox4Nano simulates at regional to continental scale for screening level fate assessment. It can also be used to determine the maximum allowed production volume of NPs in EU since production volume is linear with the predicted milieu concentration.

  • Nanosafer tool

    08 september 2017

    Online control banding and risk management tool for manufactured nanomaterials. Hazard assessment and case-specific exposure potentials are combined into an integrated assessment of risk levels expressed in control bands with associated risk management recommendations. It can also be used to assess and manage emissions from nanoparticle-forming processes. Uses data on material properties, processes and production facilities to estimate occupational risk. The tool uses the Risk Quotient (i.e. the ratio of an exposure dose to a human effect threshold) to estimate risk deterministically. The tool is capable of estimating exposure from spray processes and it can perform nano-specific Hazard Assessment based on read-across between NPs based on specific material properties and hazard indicators, tested for performance against in vivo experiments.

  • Consexpo Nano Tool

    08 september 2017

    The ConsExpo nano tool can be used to estimate inhalation exposure to nanomaterials in consumer spray products. To run the model, user input on different exposure determinants such as the product and its use, the nanomaterial and the environmental conditions is required. Exposure is presented in different measures. The outcome of the assessment is an alveolar load in the lungs as one of the most critical determinants of inflammation of the lungs is both the magnitude and duration of the alveolar load of a nanomaterial. To estimate the alveolar load arising from the use of nano-enabled spray products, ConsExpo nano combines models that estimate the external aerosol concentration in indoor air, with models that estimate the deposition in and clearance of inhaled aerosol from the alveolar region.

  • Lean Business Canvas, safety and society check

    08 september 2017

    This tool helps researchers to identify, develop and validate product and business ideas with the help of modern business tools such as the Lean Business Model Canvas. While formulating their business case, researchers perform a Safety and Society Check as part of the Lean Business Canvas, as applied within the NanoNextNL Valorisation Programme. Risk levels for safety and society are indicated with arrows based on expertise of business case owners and an independent expert; left for safety and right for society.

  • Golden Egg Check

    08 september 2017

    The Golden Egg Check is an online software tool to shape ideas into business cases and to attract funding from investors. Golden Egg Check is used by thousands of innovators within corporate, startup and scale-up companies and their supporters like incubators, educators, and investors and other funding programs.

  • Sustainable Diets

    23 april 2014

    The rising concern on global food security and climate change has led to an increased interest in sustainable and healthy diets. Food production and consumption determines 20-30% of total environmental impact for example through greenhouse gas emissions. Individuals can directly influence this share by their own choice of food.

  • Salt

    18 maart 2014

    Excessive salt intake has been associated with hypertension and increased cardiovascular disease morbidity and mortality. Reducing salt intake is considered an important public health strategy.

  • Societal incubator

    08 september 2017

    This experimental tool is used to explore the sentiments/uncertainties of involved stakeholders and is under construction. The idea behind a societal incubator is how to connect safe and responsible use to innovation and engineering. Within NanoNextNL the idea of a societal incubator explores the benefits and applicability of an equivalent of a business incubator, combined with the value of open dialogues and participants eager to give shape to Safe-by-Design.

  • CENARIOS® risk management and monitoring system

    08 september 2017

    CENARIOS® (Certifiable Nanospecific Risk Management and Monitoring System) enables identification, analysis and assessment of the potential risks and opportunities involved in nanotechnology and their possible impacts on people.

  • NanoCRED

    19 september 2017

    This is a framework for reliability and relevance evaluation of ecotoxicity data for nanomaterials. The nanoCRED evaluation criteria, and accompanying guidance, were developed to be used in combination with those developed through the ‘Criteria for Reporting and Evaluating Ecotoxicity Data (CRED)’ project. This approach can accommodate all types of nanomaterials, all types of aquatic ecotoxicity studies, and qualitative as well as quantitative data evaluation requirements. Furthermore, it is practically feasible to implement and directly applicable in European as well as international regulatory frameworks.

  • One box-model for accident situations in laboratories (Walser et al 2012)

    19 september 2017

    Authors conclude that one measurement device is appropriate and sufficient for a screening assessment of workplace exposure to NP for events with NP concentrations orders of magnitude higher than the backgrond concentration and workplaces with good air mixing conditions.

  • Water quality standards for PFOA : A proposal in accordance with the methodology of the Water Framework Directive

    15 september 2017
  • Indicatorenset voor het stelsel van publieke gezondheidszorg: ontwikkeling compacte set en duiding - samenvatting -

    14 september 2017
  • Wat ligt er op ons bord? : Methodologisch achtergrondrapport bij 'Veilig, gezond en duurzaam eten in Nederland'

    04 september 2017
  • What is on our plate? : Safe, healthy and sustainable diets in the Netherlands

    04 september 2017
  • What is on our plate? : Safe, healthy and sustainable diets in the Netherlands (Background report)

    04 september 2017
  • Set of indicators for the public healthcare system: development of the compact set and interpretation - summary -

    14 september 2017
  • What is on our plate? : Safe, healthy and sustainable diets in the Netherlands

    04 september 2017

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