Olling M ,
Berende PLM ,
Derks HJGM ,
Liem AKD ,
Everts H ,
Jong APJM de
English Abstract After the investigation of the toxicokinetics of PCDD's
and PCDF's in lactating cows from the Lickebaert area, the kinetics of these
compounds was studies in non-lactating cows and is described in this report.
The mean half-lives in three cows of the different congeners are between 160
and 280 days. There is no simple correlation between these half-lives and
the degree of chlorination of the compounds in non-lactating cows. For
accurate calculation of the half lives the exact volume of distribution
(i.e. the fat compartment) and the changes in this compartment during the
experiment must be known.