Visser T ,
Vredenbregt MJ ,
Jong APJM de ,
Ginkel LA van ,
Rossum HJ van ,
Stephany RW
18 p
in Dutch
1993
Toon Nederlands
English Abstract The usefulness of cryotrapping gas
chromatography-Fourier transform infrared spectrometry (GC-FTIR) for the
residue analysis of the beta-agonists clenbuterol, mabuterol and salbutamol
in bovine urine and tissues has been evaluated. It is demonstrated that the
technique is able to detect and identify the trimethylsilyl derivatives of
these compounds in urine and liver extracts of veal calves and cattle. The
obtained limit of identification is approximately 1 nanogram per microliter
extract injected on column which is equivalent to 2.5 microgram per liter
or kilogram of the original sample. It is anticipated that the technique
may develop as a valuable method for univocal confirmation of the presence
of residues, particularly in addition to gas chromatography-mass
spectrometry (GC-MS).
