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Huijbregts PPCW , Feskens EJM , Seidell JC

53 p in Dutch   1994

Toon Nederlands

English Abstract
The feasibility of monitoring the prevalence of diabetes mellitus within the framework of the Monitoring Project on Cardiovascular Disease Risk Factors was investigated. Furthermore, different methods for the measurement of body girths were compared. Data were collected in 1992 from 155 men and 156 women from Doetinchem, aged 20-59 years. In 129 men and 127 women of this group a glucose tolerance test (GTT) was done as well as a non-fasting measurement of serum glucose and insulin. In addition, we used data of 436 men aged 70-89 years, who were investigated in 1990 in a follow-up round of the Zutphen Study. Using multiple regression analysis we assessed the fasting and 2-hr glucose level from the non-fasting glucose level, the time since the last meal, and the carbohydrate level of this meal. This was also done for insuline. A low sensitivity was found (33%). We therefore concluded that non-fasting glucose was not a very good indicator of diabetes mellitus. However it was observed that 15% of the participants had not had breakfast on the morning of the investigation. We therefore recommend to take non-fasting blood samples from the participants and to ask at what time the last meal was consumed. It will then be possible to predict diabetes mellitus reasonably well in the fasting group. In the other part of the study four methods for the measurement of body girths were compared. Data were collected from 135 men and 131 women aged 20-59 years from Doetinchem. The methods investigated were: a measurement according to WHO-criteria, a measurement carried out by the participants themselves, a fully dressed measurement, and a reference measurement. The fully dressed measurement correlated well with the reference measurement. However, the correlation between the reference measurement and the measurement according to WHO-criteria was somewhat lower in women. Furthermore, it appeared during the course of the study that the practical feasibility of the measurement according to WHO-criteria was high. This method has therefore been incorporated in the MORGEN-project since 1-1-1993.


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( 1994-01-31 )