Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof 719102021

Mutagene stoffen en risico's voor natuurlijke populaties. Onderzoek met Daphnia magna als modelorganisme. II. Experimenten met een mutagene stof

[ [Mutagenic substances and natural populations at risk. Research with Daphnia magna as a model organism. II. Experiments with a mutagenic substance.] ]

Vaal MA, Breedijk I, Dekker MP, Mout HCA, Kramers PGN, Roghair CJ

38 p in Dutch 1992

RIVM Rapport 719102021

Toon Nederlands

English Abstract
Daphnia magna is used as a model organism to study the consequences of the impact of mutagenic chemicals to natural populations. Adult daphnids were exposed to a mutagenic test compound to test whether their offspring showed effects of induced mutations at exposure levels lower than the No Observed Effect Concentration for growth and reproduction. Life-history parameters were used as test parameters. A concentration-related toxic effect to reproduction could be measured reproducibly in the exposed adult daphnids. However, no indication of a mutagenic effect could be detected in their offspring. This may have been due to the inadequateness of the system to detect induced genetic change.

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