The centre focuses on the health impacts and risks to people of chemical and biological agents, with special attention to medicines, medical products, tobacco, consumer products, diet and food components, and interaction with life style factors.
These impacts and risks are identified, analysed, qualified
and where possible quantified. Advice is provided to the Dutch
Ministries of Public Health, Welfare and Sport, of Social Affairs
and Employment, and of Economic Affairs, Health Care Inspectorate,
Food and Consumer Products Safety Authority, and in national and
Advice and studies relate to:
Risks and impact on public health of chemical and biological
agents, particularly biological medicines, chemical pharmaceutical
products, medical technology, tobacco products, drugs and
Innovation in strategies for risk evaluation of chemical
substances and medical products, directed particularly to
carcinogenesis, mutagenesis, reproduction and immuno-toxicology and
sensitisation. Particular attention is given to alternatives to
Safe application of medicines and medical products, and other
aspects of pharmaceutical care.
Efficacy of products and the health care cycle with regard to
medicines and medical products.
Determinants of chronic diseases and particularly healthy
ageing, nutritional status and lifestyle, for instance, disturbance
of day-night rhythm.
Technological innovations in health care.
The centre signals new developments in these areas, and carries
out research to assess health impacts, and has access to various
specialist laboratories for this research. Various legal and
reference tasks are carried out on tobacco products, vaccines and
blood products, and on medicines as the Official Medicines Control