Modification date 06/03/2022 - 13:59
COVID-19 vaccines in the Netherlands
- Moderna (Spikevax) - The Moderna vaccine is an mRNA vaccine.
- Pfizer/BioNTech (Comirnaty) - The Pfizer/BioNTech vaccine (brand name: Comirnaty) is an mRNA vaccine.
- AstraZeneca (Vaxzevria) - The AstraZeneca vaccine is a vector vaccine. See also the frequently asked questions about AstraZeneca.
Janssen. - The Janssen vaccine is a vector vaccine.
- Novavax. - The Novavax vaccine is a protein-based vaccine. Read more about the Novavax vaccine.
Read more about these vaccines on Government.nl.
Types of COVID-19 vaccines
- The COVID-19 vaccines made by Pfizer/BioNTech and by Moderna are RNA vaccines. These RNA vaccines contain a protective envelope of lipids (fat) with an instruction (code) that tells your cells to make spike proteins. These are the spiky protrusions on the exterior of the coronavirus. The immune system recognises the spike proteins as foreign substances and starts making antibodies.
- The vaccines made by AstraZeneca and by Janssen are vector vaccines. The vector vaccines contain an inactivated cold virus (that cannot replicate) with an instruction (code) that tells your cells to make spike proteins. The immune system reacts by producing antibodies, just as it does in response to the RNA vaccines.
- The Novavax vaccine is a protein subunit vaccine. The vaccine contains very small particles of spike protein, which have been produced in a laboratory. It also contains an adjuvant: a substance that intensifies the body’s immune response to the protein. After vaccination, the body responds by producing antibodies against the spike protein. If the body encounters the SARS-COV-2 virus, the immune system recognises the spike proteins on the virus. In response, the immune system starts producing antibodies. The vaccine is broken down naturally by the body.
There is no gelatin, chicken protein or antibiotics in RNA vaccines made by Pfizer/BioNTech and Moderna or in the vector vaccines made by AstraZeneca and Janssen.