Prediction of In Vivo Behaviour of Nanoparticles Using PBPK Models: Key Findings and Recommendations

… based pharmacokinetic (PBPK) models to better predict their transport and elimination. Insufficient data on kinetic … (PBPK) models to more accurately predict the transport and elimination of nanoparticles in biological … and release rates are at various stages of development. For transport across the intestinal barrier, the  OECD guidance …