Titel Auteurs Gepubliceerd in:
A comparison of gene expression responses in rat whole embryo culture and in vivo: time-dependent retinoic acid-induced teratogenic response Robinson J.F., Verhoef A., Pennings J.L.A., Pronk T.E., Piersma A.H. Toxicol Sci 2012; 126(1):242-54
A framework for quantifying net benefits of alternative prognostic models Rapsomaniki E., White I.R., Wood A.M., Thompson S.G., Emerging Risk Factors Collaboration, Verschuren W.M.M., Blokstra A., Bueno de Mesquita H.B. Stat MedMedical Exposure Directive 2012; 31(2):114-30
A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23 Wu X., Scelo G., Purdue M.P., Rothman N., Johansson M., Ye Y., Wang Z., Zelenika D, Moore L.E., Wood C.G., Prothortchouk E., Gaborieau V., Jacobs K.B., Chow W.H., Toro J.R., Zaridze D., Lin J., Lubinski J., Trubicka J., Szeszenia-Dabrowska N., Lissowska J., Rudnai P., Bueno de Mesquita H.B., et.al. Hum Mol Genet 2012; 21(2):456-62
A quantitative approach to assess the potency of skin sensitizers in the elicitation phase Ezendam J., Vermeulen J.P., de Klerk A., de Jong W.H., van Loveren H. Toxicology 2012; 299(1):20-4
A regulatory approach to assess the potency of substances toxic to the reproduction Muller A., Blaude M.N., Ihlemann C., Bjorge C., Ohlsson A., Gebel T. Regul Toxicol Pharmacol 2012; 63(1):97-105
A review of mammalian toxicity of ZnO nanoparticles Vandebriel R.J., de Jong W.H. Nanotechnol Sci Applications 2012; 5(1):61-71
A review of toxicogenomic approaches in developmental toxicology Robinson J.F., Pennings J.L., Piersma A.H. Methods Mol Biol 2012; 889:347-71
A risk model for lung cancer incidence Hoggart C., Brennan P., Tjonneland A., Vogel U., Overvad K., Nautrup Ostergaard J., Kaaks R., Canzian F., Boeing H., Steffen A., Trichopoulou A., Bamia C., Trichopolous D., Johansson M., Palli D., Krogh V., Tumino R., Sacerdote C., Panico S., Boshuizen H., Bueno de Mesquita H.B., Peeters P.H.M., Lund E., Torhild Gram I., Braaten T., Rodriguez L., Agudo A., Sanchez-Cantalejo E., Arriolo L., Chirlaque M.D., Barricarte A., Rasmuson T., Khaw K.T., Wareham N., Allen N.E., Riboli E., Vineis P. Cancer Prev Res 2012; 5(6):834-46
A structured approach to exposure based waiving of human health endpoints under REACH developed in the OSIRISinformation system project Marquart H., Meijster T., van de Bovenkamp M., ter Burg W., Spaan S., van Engelen J. Regul Toxicol Pharmacol 2012; 62(2):231-40
Age of onset in health impact assessment of chemical substances Bokkers B.G.H., Schuur A.G., Zeilmaker M.J. Int J Environ Health 2012; 6(1):37-47
Alcohol consumption and pancreatic cancer: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4) Lucenteforte E., La Vecchia C., Silverman D., Petersen G.M., Bracci P.M., Ji B.T., Bosetti C., Li D., Gallinger S., Miller A.B., Bueno de Mesquita H.B., Talamini R., Polesel J., Ghadirian P., Baghurst P.A., Zatonski W., Fontham E., Bamlet W.R., Holly E.A., Gao Y.T., Negri E., Hassan M., Cotterchio M., Su J., Maisonneuve P., Boffetta P., Duell E.J. Ann Oncol 2012; 23(2):374-82
Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study Beulens J.W.J., van der Schouw Y.T., Bergmann M.M., Rohrmann S., Schulze M.B., Buijsse B., Grobbee D.E., Arriola L., Cauchi S., Tormo M.J., Allen N.E., van der A D.L., Balkau B., Boeing H., Clavel-Chapelon F., de Lauzon-Guillan B., Franks P., Froguel P., Gonzales C., Halkjaer J., Huerta J.M., Kaaks R., Key T.J., Khaw K.T., Krogh V., Molina-Montes E., Nilsson P., Overvad K., Palli D., Panico S., Quiros J.R., Ronaldsson O., Romieu I., Romaguera D., Sacerdote C., Sanchez M.J., Spijkerman A.M.W., Teucher B., Tjonneland A., Tumino R., Sharp S., Forouhi N.G., Langenberg C., Feskens E.J.M., Riboli E., Wareham N.J. J Intern Med 2012; 272(4):358-70
Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study Ferrari P., McKay J.D., Jenab M., Brennan P., Canzian F., Vogel U., Tjonneland A., Overvad K., Tolstrup J.S., Boutron-Ruault M.C., Clavel-Chapelon F., Morois S., Kaaks R., Boeing H., Bergmann M., Trichopoulou A., Katsoulis M., Trichopoulos D., Krogh V., Panico S., Sacerdote C., Palli D., Tumino R., Peeters P.H., van Gils C.H., Bueno de Mesquita H.B., Vrieling A., Lund E., Hjartaker A., Agudo A., Suarez L.R., Arriola L., Chirlaque M.D., Ardanaz E., Sanchez M.J., Manjer J., Lindkvist B., Hallmans G., Palmqvist R., Allen N., Key T., Khaw K.T., Slimani N., Romieu I., Boffetta P., Romaguera D., Norat T., Riboli E. EurErasmus Universiteit Rotterdam J Clin Nutr 2012; 66(12):1303-8
Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects Peiser M., Tralau T., Heidler J., Api A.M., Arts J.H.E., Basketter D.A., English J., Diepgen T.L., Fuhlbrigge R.C., Gaspari A.A., Johansen D.E., Karlberg A.T., Kimber I., Lepoittevin J.P., Liebsch M., Maibach H.I., Martin S.F., Merk H.F., Platzek T., Rustemeyer T., Schnuch A., Vandebriel R.J., White I.R., Luch A. Cell Mol Life Sci 2012; 69(5):763-81
An improved model to predict physiologically based model parameters and their inter-individual variability from anthropometry Bosgra S., van Eijkeren J., Bos P., Zeilmaker M., Slob W. Crit RevRevalidatiecentra Toxicol 2012; 42(9):751-67
An optimized gene set for transcriptomics based neurodevelopmental toxicity prediction in the neural embryonic stem cell test Pennings J.L.A., Theunissen P.T., Piersma A.H. Toxicology 2012; 300(3):158-67
Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users de Jong H.J.I., Vandebriel R.J., Saldi S.R.F., van Dijk L., van Loveren H., Cohen Tervaert J.W., Klungel O.H. Pharmacoepidemiol Drug Saf 2012; 21(8):835-43
Anthelmintic drug residues in beef: UPLC-MSmicrosoft/MS method validation, European retail beef survey, and associated exposure and risk assessments Cooper K.M., Whelan M., Kennedy D.G., Trigueros G., Cannavan A., Boon P.E., Wapperom D., Danaher M. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2012; 29(5):746-60
Application of the BRAFO tiered approach for benefit-risk assessment to case studies on dietary interventions Verhagen H., Andersen R., Antoine J-M., Finglas P., Hoekstra J., Kardinaal A., Nordmann H., Pekcan G., Pentieva K., Sanders T.A., van den Berg H., van Kranen H., Chiodini A. Food Chem toxicol 2012; 50(Supp 4):710-23
Application of the BRAFO tiered approach for benefit-risk assessment to case studies on dietary interventions Verhagen H., Andersen R., Antoine J-M., Finglas P., Hoekstra J., Kardinaal A., Nordmann H., Pekcan G., Pentieva K., Sanders T.A., van den Berg H., van Kranen H., Chiodini A. Food Chem Toxicol 2012; 50(suppl 4):S710-23
Application of the BRAFO-tiered approach for benefit-risk assessment to case studies on natural foods Watzl B., Gelencsér E., Hoekstra J., Kulling S., Lydeking-Olsen E., Rowland I., Schilter B., van Klaveren J., Chiodini A. Food Chem Toxicol 2012; 50(Supp 4):699-709
Approaches to the safety assessment of engineered nanomaterials (ENMengineered nanomaterial) in food Cockburn A., Bradford R., Buck N., Constable A., Edwards G., Haber B., Hepburn P., Howlett J., Kampers F., Klein C., Radomski M., Stamm H., Wijnhoven S., Wildermann T. Food Chem Toxicol 2012; 50(6):2224-42
Association between FTOperiodiek overleg van afzonderlijke huisartsengroepen in een regio variant and change in body weight and its interaction with dietary factors: The DiOGenes Study Vimaleswaran K.S., Angquist L., Hansen R.D., van der A D.L., Bouatia-Naji N., Holst C., Tjonneland A., Overvad K., Uhre Jakobsen M., Boeing H., Meidtner K., Palli D., Masala G., Saris W.H.M., Feskens E.J.M., Wareham N.J., Sorensen T.I.A., Loos R.J.F. Obesity 2012; 20(8):1669-74
Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the breast and prostate cancer cohort consortium Machiela M.J., Lindstrom S., Allen N.E., Haiman C.A., Albanes D., Barricarte A., Berndt S.I., Bueno de Mesquita H.B., Chanock S., Gaziano M., Gapstur S.M., Giovannucci E., Henderson B.E., Jacobs E.J., Kolonel L.N., Krogh V., Ma J., Stampfer M.J., Stevens V.L., Stram D.O., Tjonneland A., Travis R., Willett W.C., Hunter D.J., le Marchand L., Kraft P. Am J Epidemiol 2012; 176(12): 1121-9
Auditory neuropathy in a low-risk population: a review of the literature Korver A.M.H., van Zanten G.A., Meuwese-Jongejeugd A., van Straaten H.L.M., Oudesluys-Murphy A.M. Int J Pediatr Otorhinolaryngol 2012; 76(12):1708-11
Bias in protein and potassium intake collected with 24-h recalls (EPIC-Soft) is rather comparable across European populations Crispim S.P., Geelen A., de Vries J.H.M., Freisling H., Souverein O.W., Hulshof P.J.M., Ocke M.C., Boshuizen H., Andersen L.F., Ruprich J., de Keizer W., Huybrechts I., Lafay L., de Magistris M.S., Ricceri F., Tumino R., Krogh V., Bueno de Mesquita H.B., Beulens J.W.J., Boutron-Ruault M.C., Naska A., Crowe F.L., Boeing H., McTaggart A., Kaaks R., van 't Veer P., Slimani N. Eur J Nutr 2012; 51(8):997-1010
Biological effects of add-on eicosapentaenoic acid supplementation in diabetes mellitus and co-morbid depression: a randomized controlled trial Mocking R.J.T., Assies J., Bot M., Jansen E.H.J.M., Schene A.H., Pouwer F. PlosPlos One One 2012; 7(11):e49431
Biomarker discovery using a comparative omics approach in a mouse model developing heterogeneous mammary cancer subtypes Pennings J.L.A., van Dycke K.C., van Oostrom C.T., Kuiper R.V., Rodenburg W., de Vries A. Proteomics 2012; 12(13):2149-57
Biomarkers of oxidative stress and risk of developing colorectal cancer: a cohort-nested case-control study in the European Prospective Investigation into Cancer and Nutrition Leufkens A.M., van Duijnhoven F.J.B., Woudt S.H.S., Siersema P.D., Jenab M., Jansen E.H.J.M., Pischon T., Tjonneland A., Olsen A., Overvad K., Boutron-Ruault M.C., Clavel Chapelon F., Morois S., Palli D., Pala V., Tumino R., Vineis P., Panico A., Kaaks R., Lukanova A., Boeing H., Aleksandrova K., Trichopoulou A., Trichopoulos D., Dilis V., Peeters P.H., Skeie G., Gonzalez C.A., Arouelles M., Sanchez M.J., Dorronsoro M., Huerta J.M., Ardanaz E., Hallmans G., Palmqvist R., Khaw K.T., Wareham N., Allen N.E., Crowe F.L., Fedirko V., Norat T., Riboli E., Bueno de Mesquita H.B. Am J Epidemiol 2012; 175(7):653-63
Biowaiver monograph for immediate release solid oral dosage forms: acetylsalicylic acid Dressman J.B., Nair A., Abrahamsson B., Barends D.M., Groot D.W., Kopp S., Langguth P., Polli J.E., Shah V.P., Zimmer M. J Pharm Sci 2012; 101(8):2653-67
Biowaiver monographs for immediate release solid oral dosage forms: Stavudine Silva A.L.., Christofoletti R., Storpirtis S., Sousa V.D., Junginger H.E., Shah V.P., Stavchansky S., Dressman J.B., Barends D.M. J Pharm Sci 2012; 101(1):10-6
Biowaiver monographs for immediate release solid oral dosage forms: Stavudine Silva A.L.., Christofoletti R., Storpirtis S., Sousa V.D., Junginger H.E., Shah V.P., Stavchansky S., Dressman J.B., Barends D.M. J Pharm Sci 2012; 101(1):10-6
Biowaiver monographs for immediate-release solid oral dosage forms: amodiaquine hydrochloride Nair A., Abrahamsson B., Barends D.M., Groot D.W., Kopp S., Polli J.E., Shah V.P., Dressman J.B. J Pharm Sci 2012; 101(12):4390-401
Biowaiver monographs for immediate-release solid oral dosage forms: ketoprofen Shohin I.E., Kulinich J.I., Ramenskaya G.V., Abrahamsson B., Kopp S., Langguth P., Polli J.E., Shah V.P., Groot D.W., Barends D.M., Dressman J.B. J Pharm Sci 2012; 10(10):3593-603
Biowaiver monographs for immediate-release solid oral dosage forms: Primaquine phosphate Nair A., Abrahamsson B., Barends D.M., Groot D.W., Kopp S., Polli J.E., Shah V.P., Dressman J.B. J Pharm Sci 2012; 101(3):936-45
Biowaiver monographs for immediate-release solid oral dosage forms: Quinine sulfate Strauch S., Dressman J.B., Shah V.P., Kopp S., Polli J.E., Barends D.M. J Pharm Sci 2012; 101(2):499-508
Body size and risk of differentiated thyroid carcinomas: findings from the EPIC study Rinaldi S., Lise M., Clavel Chapelon F., Boutron-Ruault M.C., Guillas G., Overvad K., Tjonneland A., Halkjaer J., Lukanova A., Kaaks R., Bergmann M.M., Boeing H., Trichopoulou A., Zylis D., Valanou E., Palli D., Agnoli C., Tumino R., Polidoro S., Mattiello A., Bueno de Mesquita H.B., Peeters P.H., Weiderpass E., Lund E., Skeie G., Rodriguez L., Travier N., Sanchez M.J., Amiano P., Huerta J.M., Ardanaz E., Rasmuson T., Hallmans G., Almquist M., Manjer J., Tsilidis K.K., Allen N.E., Khaw K.T., Wareham N., Byrnes G., Romieu I., Riboli E., Franceschi S. Int J Cancer 2012; 131(6):e1004-14
BRAFO tiered approach for benefit-risk assessment of foods Hoekstra J., Hart A., Boobis A., Claupein E., Cockburn A., Hunt A., Knudsen I., Richardson D., Schilter B., Schutte K., Torgerson P.R., Verhagen H., Watzl B., Chiodini A. Food Chem Toxicol 2012; 50 (Suppl 4):684-98
Candidate Down syndrome screening biomarkers from a mouse model Pennings J., Rodenburg W. Prenatal Screening Perspectives 2012: 17(1):10
Capsule shells adulterated with tadalafil Venhuis B.J., Tan J., Vredenbregt M.J., Ge X., Low M-Y., de Kaste D. Forensic Sci Int 2012; 214(1-3):e20-2
Carcinogenic activity of benzo[a]pyrene in a 2 year oral study in Wistar rats Wester P.W., Muller J.J., Slob W., Mohn G.R., Dortant P.M., Kroese E.D. Food Chem Toxicol 2012; 50(3-4):927-35
Changes in lymphocyte subsets in workers exposed to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) Hosnijeh F.S., Lenters V., Boers D., Portengen L., Baeten E., Bueno de Mesquita H.B., Heederik D.J.J., Bloem A.C., Vermeulen R. Occup Environ Med 2012; 69(11):781-6
Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PANC4) Bosetti C., Lucenteforte E., Silverman D.T., Petersen G., Bracci P.M., Ji B.T., Negri E., Li D., Risch H.A., Olson S.H., Gallinger S., Miller A.B., Bueno de Mesquita H.B., Talamini R., Polesel J., Ghadirian P., Baghurst P.A., Zatonski W., Fontham E., Bamlet W.R., Holly E.A., Bertuccio P., Gao Y.T., Hassan M., Yu H., Kurtz R.C., Cotterchio M., Su J., Maisonneuve P., Duell E.J., Boffetta P., La Vecchia C. Ann Oncol 2012; 23(7):1880-8
Cigarette smoking and risk of histological subtypes of epithelial ovarian cancer in the EPIC cohort study Gram I.T., Lukanova A., Brill I., Braaten T., Lund E., Lundin E., Overvad K., Tjonneland A., Clavel-Chapelon F., Chabbert-Buffet N., Bamia C., Trichopolou A., Zylis D., Masala G., Berrino F., Galasso R., Tumino R., Sacerdote C., Gavrilyuk O., Kristiansen S., Rodriguez L., Bonet C., Huerta J.M., Barricarte A., Sanchez M.J., Dorronsoro M., Jirstrom K., Almquist M., Idahl A., Bueno de Mesquita H.B., Braem M., Onland-Moret C., Tsilidis K.K., Allen N.E., Fedirko V., Riboli E., Kaaks R. Int J Cancer 2012; 130(9):2204-10
Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time Reiling E., Lyssenko V., Boer J.M.A., Imholz S., Verschuren W.M.M., Isomaa B., Tuomi T., Groop L., Dolle M.E.T. Eur J Hum Genet 2012; 20(6):696-700
Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis Braem M.G.M., Onland-Moret N.C., Schouten L.J., Tjonneland A., Hansen L., Dahm C.C., Overvad K., Lukanova A., Dossus L., Floegel A., Boeing H., Clavel-Chapelon F., Chabbert-Buffet N., Fagherazzi G., Trichopoulou A., Benetou V., Goufa I., Pala V., Galasso R., Mattiello A., Sacerdote C., Palli D., Tumino R., Gram I.T., Lund E., Gavrilyuk O., Sanchez M.J., Quiros R., Gonzales C.A., Dorronsoro M., Castano J.M., Gurrea A.B., Idahl A., Ohlson N., Lundin E., Jirstrom K., Wirfalt E., Allen N.E., Tsilidis K.K., Khaw K.T., Bueno de Mesquita H.B., Dik V.K., Rinaldi S., Fedirko V., Norat T., Riboli E., Kaaks R., Peeters P.H.M. Am J Clin Nutr 2012; 95(5):1172-81
Cognitieveschade door intensief gebruik en overdoses van GHBgamma-hydroxybutaanzuur van Amsterdam J.G.C., Brunt T.M., McMaster M.T.B., Niesink R., van Noorden M.S., van den Brink W. Tijdschr Psychiatrie 2012; 54(12):1001-10
Combined impact of lifestyle factors on prospective change in body weight and waist circumference in participants of the EPIC-PANACEA study May A.M., Romaguera D.., Travier N., Ekelund U., Bergmann M.M., Kaaks R., Teucher B., Steffen A., Boeing H., Halkjaer J., Tjonneland A., Uhre Jakobsen M., Overvad K., Dartois L., Fagherazzi G., Boutron-Ruault M.C., Quiros J.R., Agudo A., Gonzalez C., Sanchez M.J., Amiano P., Huerta J.M., Ardanaz E., Wareham N.J., Crowe F.L., Naska A., Orfanos P., Trichopoulou A., Palli D., Agnoli C., Tumino R., Vineis P., Panico S., Bueno de Mesquita H.B., Verschuren M., Drake I., Sonestedt E., Braaten T., Rinaldi S., Romieu I., Slimani N., Norat T., Riboli E., Peeters P.H.M. Plos One 2012; 7(11):e50712
Common genetic variants in prostate cancer risk prediction - Results from the NCINational Cancer Institute breast and prostate cancer cohort consortium (BPC3) Lindstrom S., Schumacher F.R., Cox D., Travis R.C., Albanes D., Allen N.E., Andriole G., Berndt S.I., Boeing H., Bueno de Mesquita H.B., Crawford E.D., Diver W.R., Gaziano J.M., Giles G.G., Giovannucci E., Gonzalez C.A., Henderson B., Hunter D.J., Johansson M., Kolonel L.N., Ma J., le Marchand L., Pala V., Stampfer M., Stram D.O., Thun M.J., Tjonneland A., Trichopoulos D., Virtamo J., Weinstein S.J., Willett W.C., Yeager M., Hayes R.B., Severi G., Haiman C.A., Chanock S.J., Kraft P. Cancer Epidemiol Biomarkers 2012; 21(3):437-44
Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp van Vliet-Ostaptchouk J.V., van Haeften T.W., Landman G.W.D., Reiling E., Kleefstra N., bilo H.J.G., Klungel O.H., de Boer A., van Diemen C.C., Wijmenga C., Boezen H.M., Dekker J.M., van 't Riet E., Nijpels G., Welschen L.M.C., Zavrelova H., Bruin E.J., Elbers C.C., Bauer F., Onland-Moret N.C., van der Schouw Y.T., Grobbee D.E., Spijkerman A.M.W., van der A D.L., Simonis-Bik A., Eekhoff E.M., Diamant M., Kramer M.H., Boomsma D.I., de GeusGeologische Dienst voor Denemarken en Groenland E.J., Willemsen G., Slagboom P.E., Hofker M.H., 't Hart L.M. Plos One 2012; 7(3):e32148
Comparison of four probabilistic models (CARES®, Calendex™, ConsExpo, and SHEDS) to estimate aggregate residential exposures to pesticides Young B.M., Tulve N.S., Egeghy P.P., Driver J.H., Zartarian V.G., Johnston J.E., Delmaar J.E., Evans J.J., Smith L.A., Glen G., Lunchick C., Ross J.H., Xue J., Barnekow D.E. J Expos Sci Environ Epidemiol 2012; 22(5):522-32
Comparison of standardised dietary folate intake across ten countries participating in the European Prospective Investigation into Cancer and Nutrition Park J.Y., Nicolas G., Freisling H., Biessy C., Scalbert A., Romieu I., Chajes V., C'huang S-C., Ericson U., Wallstrom P., RosRegionale ondersteuningsstructuur eerstelijn M.M., Peeters P.H.M., Mattiello A., Palli D., Huerta J.M., Amiano P., Halkjaer J., Dahm C.C., Trichopoulou A., Orfanos P., Teucher B., Feller S., Skeie G., Engeset D., Boutron-Ruault M.C., Clavel-Chapelon F., Crowe F., Khaw K.T., Vineis P., Slimani N. Br J Nutr 2012; 108(3):552-69
Composition and content of fatty acids in beebread of various floral origin, collected in Lithuania and prepared for storage in different ways Ceksteryte V., Jansen E.H.J.M. Chemine Technologija 2012; 60(2):57-61
Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn) Theunissen P.T., Robinson J.F., Pennings J.L.A., van Herwijnen M.H., Kleinjans J.C.S., Piersma A.H. Toxicol Appl Pharmacol 2012; 262(3):330-40
Concentration-response analysis of differential gene expression in the zebrafish embryotoxicity test following flusilazole exposure Hermsen S.A.B., Pronk T.E., van den Brandhof E.J., van der Ven L.T.M., Piersma A.H. Toxicol Sci 2012; 127(1):303-12
Concentrations of IGF-I and IGFBP-3 and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition Rohrmann S., Grote V.A., Becker S., Rinaldi S., Tjonneland A., Roswall N., Gronbaek H., Overvad K., Boutron-Ruault M.C., Clavel-Chapelon F., Racine A., Teucher B., Boeing H., Drogan D., Dilis V., Lagiou P., Trichopoulou A., Palli D., Tagliabue G., Tumino R., Vineis P., Mattielo A., Rodriguez L., Duell E.J., Molina-Montes E., Dorronsoro M., Huerta J.M., Ardanaz E., Jeumink S., Peeters P.H.M., Lindkvist B., Johansen D., Sund M., Ye W., Khaw K.T., Wareham N.J., Allen N.E., Crowe F.L., Fedirko V., Jenab M., Michaud D.S., Norat T., Riboli E., Bueno de Mesquita H.B., Kaaks R. Br J Cancer 2012; 106(5):1004-10
Consuming a diet complying with front-of-pack label criteria may reduce cholesterol levels: a modeling study Vyth E.L., Hendriksen M.A.H., Roodenburg A.J.C., Steenhuis I.H.M., van Raaij J.M.A., Verhagen H., Brug J., Seidell J.C. Eur J Clin Nutr 2012; 66(4):510-6
Cytotoxic effects in 3T3-L1 mouse and WI-38 human fibroblasts following 72hour and 7day exposures to commercial silica nanoparticles Stepnik M., Arkusz J., Smok-Pieniazek A., Bratek-Skicki A., Salvati A., Lynch I., Dawson K.A., Gromadzi'nska J., de Jong W.H., Rydzynski K. Toxicol Appl Pharmacol 2012; 263(1):89-101
Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNAdeoxyribonucleic acid repair gene XPA: Laboratory investigation Tomasevic G., Laurer H.L., Mattiason G., van Steeg H., Wieloch T., McIntosch T.K. J Neurosurg 2012; 116(6):1368-78
Dendritic cell-based in vitro assays for vaccine immunogenicity Vandebriel R.J., Hoefnagel M.H.N. Human Vaccine Immunother 2012; 8(9):1323-5
Detectable clonal mosaicism and its relationship to aging and cancer Jacobs K.B., Yeager M., Zhou W., Wacholder S., Wang Z., Rodriguez-Santiago B., Hutchinson A., Deng X., Liu C., Horner M-J., Bueno de Mesquita H.B., et.al. Nat Genet 2012; 44(6):651-8
Development and comparison of two assay formats for parallel detection of four biothreat pathogens by using suspension microarrays Janse I., Bok J.M., Hamidjaja R.A., Hodemaekers H.M., van Rotterdam B.J. Plos One 2012; 7(2):e31958
Developmental immunotoxicity testing for hazard identification Tonk E.C.M. Maastricht: University of Maastricht, 2012
Dietary factors and lung function in the general population: wine and resveratrol intake Siedlinski M., Boer J.M.A., Smit H.A., Postma D.S., Boezen H.M. Eur Respir J 2012; 39(2):385-91
Dietary factors impact on the association between CTSS variants and obesity related traits Hooton H., Angquist L., Holst C., Hager J., Rousseau F., Hansen R.D., Tjonneland A., Roswall N., van der A D.L., Overvad K., Jakobsen M.U., Boeing H., Meidtner K., Palli D., Masala G., Bouatia-Naji N., Saris W.H., Feskens E.J., Wareham N.J., Vimaleswaran K.S., Langin D., Loos R.J., Sorensen T.I., Clement K. Plos One 2012; 7(7):e40394
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Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study Zamora-Ros R., Agudo A., Luján-Barroso L., Romieu I., Ferrari P., Knaze V., Bueno de Mesquita H.B., Leenders M., Travis R.C., Navarro C., Sanchez-Cantalejo E., Slimani N., et.al. Am J Clin Nutr 2012; 96(6):1398-408
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Dietary reporting errors on 24 h recalls and dietary questionnaires are associated with BMIBody Mass Index across six European countries as evaluated with recovery biomarkers for protein and potassium intake Freisling H., van Bakel M.M.E., Biessy C., May A.M., Byrnes G., Norat T., Rinaldi S., Santucci de Magistris M., Grioni S., Bueno de Mesquita H.B., Ocke M.C., Kaaks R., Teucher B., Vergnaud A.C., Romaguera D., Sacerdote C., Palli D., Crowe F.L., Tumino R., Clavel-Chapelon F., Boutron-Ruault M.C., Khaw K.T., Wareham N.J., Trichopoulou A., Naska A., Orfanos P., Boeing H., Illner A.K., Riboli E., Peeters P.H., Slimani N. Br J Nutr 2012; 107(6):910-20
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Fruit and vegetable consumption and risk of aggressive and non-aggressive urothelial cell carcinomas in the European Prospective Investigation into Cancer and Nutrition Ros M.M., Bueno de Mesquita H.B., Kampman E., Buchner F.L., Aben K.K.H., Egevad L., Overvad K., Tjonneland A., Roswall N., Clavel-Chapelon F., Boutron-Ruault M.C., Morois S., Kaaks R., Teucher B., Weikert S., Ruesten A.V., Trichopoulou A., Naska A., Benetou V., Saieva C., Pala V., Ricceri F., Tumino R., Mattiello A., Peeters P.H.M., van Gils C.H., Gram I.T., Engeset D., Chirlaque M.D., Ardanaz E., Rodriguez L., Amanio P., Gonzalez C.A., Sanchez M.J., Ulmert D., Emstrom R., Ljungberg B., Allen N.E., Key T.J., Khaw K.T., Wareham N., Slimani N., Romieu I., Kiemenev L.A., Riboli E. Eur J Cancer 2012; 48(17):3267-77
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Gamma-glutamyltransferase, cardiovascular disease and mortality in individuals with diabetes mellitus Sluik D., Beulens J.W.J., Weikert C., van Dieren S., Spijkerman A.M.W., van der A D.L., Fritsche A., Joost H.G., Boeing H., Noethlings U. Diabetes Metab Res Rev 2012; 28(3):284-8
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Liver function tests and risk prediction of incident type 2 diabetes: evaluation in two independent cohorts Abbasi A., Bakker S.J.L., Corpeleijn E., van der A D.L., Gansevoort R.J., Gans R.O.B., Peelen L.M., van der Schouw Y.T., Stolk R.P., Navis G., Spijkerman A.M.W., Beulens J.W.J. Plos One 2012; 7(12):e51496
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Longitudinal changes in weight in relation to smoking cessation in participants of the EPIC-PANACEA study Travier N., Agudo A., May A.M., Gonzalez C., Luan J., Wareham N.J., Bueno de Mesquita H.B., van den Berg S.W., Slimani N., Rinaldi S., Clavel-Chapelon F., Boutron-Ruault M.C., Palli D., Sieri S., Mattiello A., Tumino R., Vineis P., Norat T., Romaguera D., Rodriguez L., Sanchez M.J., Dorronsoro M., Barricarte A., Huerta J.M., Key T.J., Orfanos P., Naska A., Trichopoulou A., Rohrmann S., Kaaks R., Bergmann M.M., Boeing H., Hallmans G., Johansson I., Manjer J., Lindkvist B., Jakobsen M.U., Overvad K., Tjonneland A., Halkjaer J., Lund E., Braaten T., Odysseos A., Riboli E., Peeters P.H. Prev Med 2012; 54(3-4):183-92
Long-term (in)stability of folate and vitamin B12 in human serum Jansen E.H.J.M., Beekhof P.K., Cremers J.W.J.M., Schenk E. Clin Chem Lab Med 2012; 50(10):1761-3
Long-term dietary exposure to lead in young European children: comparing a pan-European approach with a national exposure assessment Boon P.E., te Biesebeek J.D., Sioen I., Huybrechts I., Moschandreas J., Ruprich J., Turrini A, Azpiri M., Busk L., Christensen T., Kersting M., Lafay L., Liukkonen K.H., Papoutsou S., Serra-Majem L., Traczyk I., de Henauw S., van Klaveren J.D. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2012; 29(11):1701-15
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Looking beyond borders: integrating best practices in benefit-risk analysis into the field of Food and Nutrition Tijhuis M.J., Pohjola M.V., Gunnlaugsdottir H., Kalogeras N., Leino O., Luteijn J.M., Magnusson S.H., Odekerken-Schröder G., Poto M., Tuomisto J.T., Ueland O., White B.C., Holm F., Verhagen H. Food Chem Toxicol 2012; 50(1):77-93
Lower educational level is a predictor of incident type 2 diabetes in European countries: The EPIC-interact study Sacerdote C., Ricceri F., Rolandsson O., Baldi I., Chirlaque M.D., Feskens E., Bendinelli B., Ardanaz E., Arriola L., Balkau B., Bergmann M., Spijkerman A., van der A D, et.al. Int J Epidemiol 2012; 41(4):1162-73
Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: The CODAM study Wlazlo N., van Greevenbroek M.M.J., Ferreira I., Jansen E.H.J.M., Feskens E.J.M., van der Kallen C.J.H., Schalkwijk C.G., Bravenboer B., Stehouwer C.D.A. Metabolism: Clin Exp 2012; 61(12):1787-96
Meat and heme iron intake and risk of squamous cell carcinoma of the upper aero-digestive tract in the European Prospective Investigation into Cancer and Nutrition (EPIC). Steffen A., Bergmann M.M., Sanchez M.J., Chirlaque M.-D., Jakszyn P., Amiano P., Quiros R., Barricarte Gurrea A., Ferrari P., Romieu I., Fedirko V., Bueno de Mesquita H.B., et.al. Cancer Epidemiol Biomarkers Prev 2012; 21(12):2138-48
Mineral composition of commonly consumed ethnic foods in Europe Khokhar S., Garduno-Diaz S.D., Marletta L., Shahar D.R., Ireland J.D., Jansen-van der Vliet M., de Henauw S. Food Nutr Res 2012; 56:12
Multiple miscarriages are associated with the risk of ovarian cancer: Results from the european prospective investigation into cancer and nutrition Braem M.G., Onland-Moret N.C., Schouten L.J., Kruitwagen R.F., Lukanova A., Allen N.E., Wark P.A., Tjonneland A., Hansen L., Braüner C.M., Overvad K., Clavel-Chapelon F., Chabbert-Buffet N., Teucher B., Floegel A., Boeing H., Trichopoulou A., Adarakis G., Plada M., Rinaldi S., Fedirko V., Romieu I., Pala V., Galasso R., Sacerdote C., Palli D., Tumino R., Bueno de Mesquita H.B., Gram I.T., Gavrilyuk O., Lund E., Sanchez M.J., Bonet C., Chirlaque M.D., Larranaga N., Barricarte Gurrea A., Quiros J.R., Idahl A., Ohlson N., Lundin E., Jirstrom K., Butt S., Tsilidis K.K., Khaw K.T., Wareham N., Riboli E., Kaaks R., Peeters P.H.M. Plos One 2012; 7(5):e37141
Nanotoxicology: an in vitro approach van der Zee Park M. Maastricht: Universiteit Maastricht, 2012
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Nucleoride excision repair in aging and cancer Melis J.P.M. Leiden: Universiteit Leiden, 2012
Occupational exposure to organic dust increases lung cancer risk in the general population Peters S., Kromhout H., Olsson A.C., Wichmann H.E., Brüske I., Consonni D., Landi M.T., Caporaso N., Siemiatycki J., Richiardi L., Mirabelli D., Simonato L., Gustavsson P., Plato N., Jockel K.H., Ahrens W., Pohlabeln H., Boffetta P., Brennan P., Zaridze D., Cassidy A., Lissowska J., Szeszenia-Dabrowska N., Rudnai P., Fabianova E., Forastiere F., Bencko V., Foretova L., Janout V., Stücker I., Dumitru R.S., Benhamou S., Bueno de Mesquita H.B., Kendzia B., Pesch B., Straif K., Brüning T., Vermeulen R. Thorax 2012; 67(2):111-6
On the formation of bromhexine impurity E and its chromatographic behaviour Venhuis B.J., Weda M., de Kaste D., Lamme E.K. Pharmeur Bio Sci Notes 2012; 2012:135-41
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Pancreatitis and pancreatic cancer risk: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4) Duell E.J., Lucenteforte E., Olson S.H., Bracci P.M., Risch H.A., Silverman D.T., Ji B.T., Gallinger S., Holly E.A., Fontham E.H., Maisonneuve P., Bueno de Mesquita H.B., Ghadirian P., Kurtz R.C., Ludwig E., Yu H., Lowenfels A.B., Seminara D., Petersen G.M., La Vecchia C., Boffetta P. Ann Oncol 2012; 23(11):2964-70
Parameters needed to estimate the global burden of peanut allergy: systematic literature review Ezendam J., van Loveren H. Eur J Food Res Rev 2012; 2(2):46-8
Parental history of type 2 diabetes and cardiometabolic biomarkers in offspring Abbasi A., Corpeleijn E., van der Schouw Y.T., Stolk R.P., Spijkerman A., van der A D.L., Navis G., Bakker S.J.L., Beulens J.W.J. Eur J Clin Invest 2012; 42(9):974-82
Persistent organochlorine contaminants in hair samples of Northern Poland population, 1968-2009 Wielgomas B., Czarnowski W., Jansen E.H.J.M. Chemosphere 2012; 89(8):975-81
Personal hair dye use and the risk of bladder cancer: a case-control study from the Netherlands Ros M.M., Gago-Dominguez M., Aben K.K.H., Bueno de Mesquita H.B., Kampman E., Vermeulen S.H., Kiemeney L.A. Cancer Causes Control 2012; 23(7):1139-48
Phosphoproteomic analysis of mouse thymoma cells treated with tributyltin oxide: TBTO affects proliferation and energy sensing pathways Osman A.M., van Loveren H. Toxicol Sci 2012; 126(1):84-100
Phthalates dietary exposure and food sources for Belgian preschool children and adults Sioen I., Fierens T., Van Holderbeke M., Geerts L., Bellemans M., de Maeyer M., Servaes K., Vanermen G., Boon P.E., de Henauw S. Environ Int 2012; 48(1):102-8
Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition Ros M.M., Bueno de Mesquita H.B., Kampman E., Aben K.K.H., Buchner F.L., Jansen E.H.J.M., van Gils C.H., Egevad L., Overvad K., Tjonneland A., Roswall N., Boutron-Ruault M.C., Kvaskoff M., Perquier F., Kaaks R., Chang-Claude J., Weikert S., Boeing H., Trichopoulou A., Lagiou P., Dilis V., Palli D., Pala V., Sacerdote C., Tumino R., Panico S., Peeters P.H.M., Gram I.T., Skeie G., Huerta J.M., Barricarte A., Quiros J.R., Sanchez M.J., Buckland G., Larranaga N., Ehrnstrom R., Wallstrom P., Ljungberg B., Hallmans G., Key T.J., Allen N.E., Khaw K.T., Wareham N., Brennan P., Riboli E., Kiemeney L.A. Am J Clin Nutr 2012; 96(4):902-10
Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition Ros M.M., Bueno de Mesquita H.B., Kampman E., Aben K.K.H., Buchner F.L., Jansen E.H.J.M., van Gils C.H., Egevad L., Overvad K., Tjonneland A., Roswall N., Boutron-Ruault M.C., Kvaskoff M., Perquier F., Kaaks R., Chang-Claude J., Weikert S., Boeing H., Trichopoulou A., Lagiou P., Dilis V., Palli D., Pala V., Sacerdote C., Tumino R., Panico S., Peeters P.H.M., Gram I.T., Skeie G., Huerta J.M., Barricarte A., Quiros J.R., Sanchez M.J., Buckland G., Larranaga N., Ehrnstrom R., Wallstrom P., Ljungberg B., Hallmans G., Key T.J., Allen N.E., Khaw K.T., Wareham N., Brennan P., Riboli E., Kiemeney L.A. Am J Clin Nutr 2012; 96(4):902-10
Plasma cotinine levels and pancreatic cancer in the EPIC cohort study Leenders M., Chuang S.C., Dahm C.C., Overvad K., Ueland P.M., Midttun O., Vollset S.E., Tjonneland A., Halkjaer J., Jenab M., Clavel-Chapelon F., Boutron-Ruault M.C., Kaaks R., Canzian F., Boeing H., Weikert C., Trichopoulou A., Bamia C., Naska A., Palli D., Pala V., Mattiello A., Tumino R., Sacerdote C., van Duijnhoven F.J.B., Peeters P.H.M., van Gils C.H., Lund E., Rodriguez L., Duell E.J., Sanchez Perez M.J., Molina-Montes E., Huerta Castano J.M., Barricarte A., Larranaga N., Johansen D., Lindkvist B., Sund M., Ye W., Khaw K.T., Wareham N.J., Michaud D.S., Riboli E., Xun W.W., Allen N.E., Crowe F.L., Bueno de Mesquita H.B., Vineis P. Int J Cancer 2012; 131(4):997-1002
Plasma dioxin levels and cause-specific mortality in an occupational cohort of workers exposed to chlorophenoxy herbicides, chlorophenols and contaminants Boers D., Portengen L., Turner W.E., Bueno de Mesquita H.B., Heederik D., Vermeulen R. Occup Environ Med 2012; 69(2):113-8
Plasma HDLhoge dichtheid lipoproteinen cholesterol and risk of myocardial infarction: a mendelian randomisation study Voight B.F., Peloso G.M., Orho-Melander M., Frikke-Schmidt R., Barbalic M., Jensen M.K., Hindy G., Holm H., Ding E.L., Johnson T., Schunkert H., Samani N.J., Clarke R., Hopewell J.C., Verschuren W.M.M., Boer J.M.A., et.al. Lancet 2012; 380(9841):572-80
Polymorphisms in thioredoxin reductase and selenoprotein K genes and selenium status modulate risk of prostate cancer Meplan C., Rohrmann S., Steinbrecher A., Schomburg L., Jansen E., Linseisen J., Hesketh J. Plos One 2012; 7(11):e48709
Possible long-term effects of y-hydroxybutyric acid (GHB) due to neurotoxicity and overdose van Amsterdam J.G.C., Brunt T.M., McMaster M.T.B., Niesink R.J.M. Neurosci Biobehav Rev 2012; 36(4):1217-27
Prediagnostic 25-hydroxyvitamin D, VDR and CASR polymorphisms, and survival in patients with dolorectal cancer in Western European populations Fedirko V., Riboli E., Tjonneland A., Ferrari P., Olsen A., Bueno de Mesquita H.B., van Duijnhoven F.J.B., Norat T., Jansen E.H.J.M., Dahm C.C., Overvad K., Boutron-Ruault M.C., Clavel Chapelon F., Racine A., Lukanova A., Teucher B., Boeing H., Aleksandrova K., Trichopoulou A., Benetou V., Trichopoulos D., Grioni S., Vineis P., Panico S., Palli D., Tumino R., Siersema P.D., Peeters P.H., Skeie G., Brustad M., Chirlaque M.D., Barricarte A., Ramon Quiros J., Sanchez M.J., Dorronsoro M., Bonet C., Palmqvist R., Hallmans G., Key T.J., Crowe F., Khaw K.T., Wareham N., Romeiu I., McKay J., Wark P.A., Romaguera D., Jenab M. Cancer Epidemiol Biomarkers 2012; 21(4):582-93
Prediagnostic concentrations of plasma genistein and prostate cancer risk in 1,605 men with prostate cancer and 1,697 matched control participants in EPIC Travis R.C., Allen N.E., Appleby P.N., Price A., Kaaks R., Chang-Claude J., Boeing H., Aleksandrova K., Tjonneland A., Johnsen N.F., Overvad K., Ramon Quiros J., Gonzalez C.A., Molina-Montes E., Sanchez M.J., Larranaga N., Huerta Castana J.M., Ardanaz E., Khaw K.T., Wareham N., Trichopoulou A., Karapetyan T., Rafnsson S.B., Palli D., Krogh V., Tumino R., Vineis P., Bueno de Mesquita H.B., Stattin P., Johansson M., Fedirko V., Norat T., Siddiq A., Riboli E., Key T.J. Cancer Causes Control 2012; 23(7):1163-71
Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study Abbasi A., Peelen L.M., Corpeleijn E., van der Schouw Y.T., Stolk R.P., Spijkerman A.M.W., van der A D.L., Moons K.G.M., Navis G., Bakker S.J.L., Beulens J.W.J. BMJ 2012; 345:e5900
Prenatal fluoxetine exposure induces life-long serotonin 5-HT 3 receptor-dependent cortical abnormalities and anxiety-like behaviour Smit-Rigter L.A., Noorlander C.W., von Oerthel L., Chameau P., Smidt M.P., van Hooft J.A. Neuropharmacology 2012; 62(2):865-70
Presence of nano-sized silica during in vitro digestion of foods containing silica as a food additive Peters R., Kramer E., Oomen A.G., Herrera Rivera Z.E., Oegema G., Tromp P.C., Fokkink R., Rietveld A., Marvin H.J.P., Weigel S., Peijnenburg A.C.M., Bouwmeester H. ACS Nano 2012; 6(3):2441-51
Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro Zwart E.P., Schaap M.M., van den Dungen M.W., Braakhuis H.M., White P.A., van Steeg H., van Benthem J., Luijten M. Environ Mul Mutagen 2012; 53(5):376-83
Prospective study on physical activity and risk of in situ breast cancer Steindorf K., Ritte R., Tjonneland A., Fons Johnsen N., Overvad K., Ostergaard J.N., Clavel-Chapelon F., Fournier A., Dossus L., Bueno de Mesquita H.B., et.al. Cancer Epidemiol Biomarkers Prev 2012; 21(12):2009-`9
Prostate stem-cell antigen gene is associated with diffuse and intestinal gastric cancer in Caucasians: Results from the EPIC-EURGAST study Sala N., Munoz X., Travier N., Agudo A., Duell E.J., Moreno V., Overvad K., Tjonneland A., Boutron-Ruault M.C., Clavel Chapelon F., Canzian F., Kaaks R., Boeing H., Meidtner K., Trichopoulos A., Tsiotas K., Zylis D., Vineis P., Panico S., Palli D., Krogh V., Tumino R., Lund E., Bueno de Mesquita H.B., Numans M.E., Peeters P.H.M., Quiros J.R., Sanchez M.J., Navarro C., Ardanaz E., Dorronsoro M., Hallmans G., Stenling R., Manjer J., Allen N.E., Travis R.C., Khaw K.T., Jenab M., Offerhaus G.J.A., Riboli E., Gonzalez C.A. Int J Cancer 2012; 130(10):2417-27
Proteins involved in extracellular matrix dynamics are associated with respiratory syncytial virus disease severity Schuurhof A., Bont L., Hodemaekers H.M., de Klerk A., de Groot H., Hofland R.W., van de Pol A.C., Kimpen J.L.L., Janssen R. Eur Respir J 2012; 39(6):1475-81
Public health implications of standardized 25-hydroxyvitamin D levels: a decrease in the prevalence of vitamin D deficiency among older women in Germany Perna L., Haug U., Schöttker B., Mueller H., Raum E., Jansen E.H.J.M., Brenner H. Prev Med 2012; 55(3):228-32
Quantitative performance of antibody array technology in a prenatal screening setting Rodenburg W., Reimerink J.H., Imholz S., Godeke G.J., Pennings J.L.A., Schielen P.C.J.I., Koster M.P., de Vries A. Clin Chem Lab Med 2012; 50(2):325-32
Rapamycin impairs UVultraviolet induction of mutant-p53 overexpressing cell clusters without affecting tumor onset Voskamp P., Bodmann C.A., Rebel H.G., Koehl G.E., Tensen C.P., Bouwes Bavinck J.N., El Ghalbzouri A., van Kranen H.J., Willemze R., Geissler E.K., de Gruijl F.R. Int J Cancer 2012; 131(6):1267-76
Refined hazard characterization of 3-MCPD3-monochloropropane-1,2-diol using benchmark dose modeling Rietjens I.M.C.M., Scholz G., Berg I., Schilter B., Slob W. Eur J Lipid Sci Technol 2012; 114(10):1140-7
Relative parameter sensitivity in prenatal toxicity studies with substances classified as developmental toxicants Rorije E., van Hienen F.J.W., Dang Z.C., Hakkert B.H., Vermeire T., Piersma A.H. Reprod Toxicol 2012; 34(2):284-90
Relative sensitivity of developmental and immune parameters in juvenile versus adult male rats after exposure to di(2-ethylhexyl) phthalate Tonk E.C.M., Verhoef A., Gremmer E.R., van Loveren H., Piersma A.H. Toxicol Appl Pharmacol 2012; 260(1):48-57
Replication of five prostate cancer loci identified in an Asian population: results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3) Lindstrom S., Schumacher F.R., Campa D., Albanes D., Andriole G., Berndt S.I., Bueno de Mesquita H.B., Chanock S.J., Diver W.R., Ganziano J.M., Gapstur S.M., Giovannucci E., Haiman C.A., Henderson B., Hunter D.J., Johansson M., Kolonel L.N., le Marchand L., Ma J., Stampfer M., Stevens V.L., Trichopoulos D., Virtamo J., Willett W.C., Yeager M., Hsing A.W., Kraft P. Cancer Epidemiol Biomarkers Prev 2012; 21(1):212-6
Response to Bosch et al.: Nanosilica? clarifications are necessary! [Letter to the editor] Dekkers S., Krystek P., Peters R.J.B., Lankveld D.P.K., Bokkers B.G.H., van Hoeven-Arentzen P.H., Bouwmeester H., Oomen A.G. Nanotox 2012; 6(6):612-3
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Risk assessment of patulin intake from apple containing products by young children Brandon E.F.A., Baars A.J., te Biesebeek J.D., Oomen A.G., Bakker M.I., de Heer C. World Mycotoxin J 2012; 5(4):391-403
Self-rated health and mortality in individuals with diabetes mellitus: prospective cohort study Wennberg P., Rolandsson O., Jerdén L., Boeing H., Sluik D., Kaaks R., Teucher B., Spijkerman A.M.W., Bueno de Mesquita H.B., Dethlefsen C., Nilsson P., Noethlings U. BMJ Open 2012; 2(1):e000760
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study Povel C.M., Boer J.M.A., Onland-Moret N.C., Dolle M.E.T., Feskens E.J.M., van der Schouw Y.T. Cardiovascular Diabetology 2012; 11:133
Smoking increases the risk for colorectal adenomas in patients with lynch syndrome Winkels R.M., Botma A., van Duijnhoven F.J.B., Nagengast F.M., Kleibeuker J.H., Vasen H.F.A., Kampman E. Gastroenterology 2012; 142(2):241-7
Social inequalities and mortality in europe - results from a large multi-national cohort Gallo V., Mackenbach J.P., Ezzati M., Menvielle G., Kunst A.E., Rohrmann S., Kaaks R., Teucher B., Boeing H., Bergmann M.M., Tjonneland A., Dalton S.O., Overvad K., Redondo M.L., Agudo A., Daponte A., Arriola L., Navarro C., Gurrea A.B., Khaw K.T., Wareham N., Key T., Naska A., Trichopoulou A., Trichopoulos D., Masala G., Panico S., Contiero P., Tumino R., Bueno de Mesquita H.B., Siersema P.D., Peeters P.P., Zackrisson S., Almquist M., Eriksson S., Hallmans G., Skeie G., Braaten T., Lund E., Illner A.K., Mouw T., Riboli E., Vineis P. Plos One 2012; 7(7):e39013
Sources of dietary protein and risk of hypertension in a general Dutch population Altorf-van der Kuil W., Engberink M.F., Geleijnse J.M., Boer J.M.A., Verschuren W.M.M. Br J Nutr 2012; 108(10):1897-903
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Standardization of misleading immunoassay based 25-hydroxyvitamin D levels with liquid chromatography tandem-mass spectrometry in a large cohort study Schöttker B., Jansen E.H.J.M., Haug U., Schomburg L., Köhrle J., Brenner H. Plos One 2012; 7(11):e48774
State of the art in benefit-risk analysis: consumer perception Ueland O., Gunnlaugsdottir H., Holm F., Kalogeras N., Leino O., Luteijn J.M., Magnusson S.H., Odekerken G., Pohjola M.V., Tijhuis M.J., Tuomisto J.T., White B.C., Verhagen H. Food Chem Toxicol 2012; 50(1):67-76
State of the art in benefit-risk analysis: economics and marketing-finance Kalogeras N., Odekerken-Schröder G., Pennings J.M.E., Gunnlaugsdottir H., Holm F., Leino O., Luteijn J.M., Magnusson S.H., Pohjola M.V., Tijhuis M.J., Tuomisto J.T., Ueland O., White B.C., Verhagen H. Food Chem Toxicol 2012; 50(1):56-66
State of the art in benefit-risk analysis: environmental health Pohjola M.V., Leino O., Kollanus V., Tuomisto J.T., Gunnlaugsdottir H., Holm F., Kalogeras N., Luteijn J.M., Magnusson S.H., Odekerken G., Tijhuis M.J., Ueland O., White B.C., Verhagen H. Food Chem Toxicol 2012; 50(1):40-55
State of the art in benefit-risk analysis: food and nutrition Tijhuis M.J., de Jong N., Pohjola M.V., Gunnlaugsdottir H., Hendriksen M., Hoekstra J., Holm F., Kalogeras N., Leino O., van Leeuwen F.X.R., Luteijn J.M., Magnusson S.H., Odekerken G., Rompelberg C.J.M., Tuomisto J.T., Ueland O., White B.C., Verhagen H. Food Chem Toxicol 2012; 50(1):5-25
State of the art in benefit-risk analysis: food microbiology Magnusson S.H., Gunnlaugsdottir H., van Loveren H., Holm F., Kalogeras N., Leino O., Luteijn J.M., Odekerken G., Pohjola M.V., Tijhuis M.J., Tuomisto J.T., Ueland O., White B.C., Verhagen H. Food Chem Toxicol 2012; 50(1):33-9
State of the art in benefit-risk analysis: introduction Verhagen H., Tijhuis M.J., Gunnlaugsdottir H., Kalogeras N., Leino O., Luteijn J.M., Magnusson S.H., Odekerken G., Pohjola M.V., Tuomisto J.T., Ueland O., White B.C., Holm F. Food Chem Toxicol 2012; 50(1):2-4
State of the art in benefit-risk analysis: medicines Luteijn J.M., White B.C., Gunnlaugsdottir H., Holm F., Kalogeras N., Leino O., Magnusson S.H., Odekerken G., Pohjola M.V., Tijhuis M.J., Tuomisto J.T., Ueland O., McCarron P.A., Verhagen H. Food Chem Toxicol 2012; 50(1):26-32
Statin-associated polymyalgia rheumatica. An analysis using WHO global individual case safety database: a case/non-case approach de Jong H.J.I., Saldi S.R.F., Klungel O.H., Vandebriel R.J., Souverein P.C., Meyboom R.H.B., Passier J.L.M., van Loveren H., Cohen Tervaert J.W. Plos One 2012; 7(7):e41289
Statins accelerate the onset of collagen type II-induced arthritis in mice Vandebriel R.J., de Jong H.J.I., Gremmer E.R., Klungel O.H., Cohen Tervaert J.W., Slob W., van der Laan J.W., van Loveren H. Arthritis Res Ther 2012; 14(2):R90
Statins accelerate the onset of collagen type II-induced arthritis in mice Vandebriel R.J., de Jong H.J.I., Gremmer E.R., Klungel O.H., Cohen Tervaert J.W., Slob W., van der Laan J.W., van Loveren H. Arthritis Res Ther 2012; 14(2):R90
Strategies for the optimisation of in vivo experiments in accordance with the 3Rs philosophy Madden J.C., Hewitt M., Przybylak K., Vandebriel R.J., Piersma A.H., Cronin M.T.D. Regul Toxicol Pharmacol 2012; 63(1):140-54
Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study van Woudenbergh G.J., Kuijsten A., Drogan D., van der A D.L., Romaguera D.., Ardanaz E., Amiano P., Barricarte A., Beulens J.W.J., Boeing H., Bueno de Mesquita H.B., Dahm C.C., Chirlaque M.D., Clavel F., Crowe F.L., Eomois P.P., Fagherazzi G., Franks P.W., Halkjaer J., Khaw K.T., Masala G., Mattiello A., Nilsson P., Overvad K., Quiros J.R., Rolandsson O., Romieu I., Sacerdote C., Sanchez M.J., Schulze M.B., Slimani N., Sluijs I., Spijkerman A.M.W., Tagliabue G., Teucher B., Tjonneland A., Tumino R., Gorouhi N.G., Sharp S., Langenberg C., Feskens E.J.M., Riboli E., Wareham N.J. Plos One 2012; 7(5):e36910
The amount and type of dairy product intake and incident type 2 diabetes: Results from the EPIC-InterAct Study Sluijs I., Forouhi N.G., Beulens J.W.J, van der Schouw Y.T., Agnoli C., Arriola L., Balkau B., Barricarte A., Boeing H., Bueno de Mesquita H.B., Clavel Chapelon F., Crowe F.L., de Lauzon-Guillain B., Spijkerman A.M.W., van der A D.L., et.al. A`m J Clin Nutr 2012; 96(2):382-90
The association of circulating adiponectin levels with pancreatic cancer risk: a study within the prospective EPIC cohort Grote V.A., Rohrmann S., Dossus L., Nieters A., Halkjaer J., Tjonneland A., Overvad K., Stegger J., Chabbert-Buffet N., Boutron-Ruault M.C., Clavel Chapelon F., Teucher B., Becker S., Montonen J., Boeing H., Trichopoulou A., Lagiou P., Trichopoulos D., Palli D., Sieri S., Tumino R., Vineis P., Mattiello A., Arguelles M., Duell J., Molina-Montes E., Larranaga N., Chirlaque M.D., Gurrea A.B., Jeurnink S.M., Peeters P.H., Ye W., Sund M., Lindkvist B., Johansen D., Khaw K.T., Wareham N., Crowe F.L., Romieu I., Rinaldi S., Jenab M., Romaguera D., Michaud D.S., Riboli S., Bueno de Mesquita H.B., Kaaks R. Int J Cancer 2012; 130(10):2428-37
The association of education with long-term weight change in the EPIC-PANACEA cohort Rohrmann S., Steinbrecher A., Linseisen J., Hermann S., May A., Luan J., Ekelund U., Overvad K., Tjonneland A., Halkjaer J., Fagherazzi G., Boutron-Ruault M.C., Clavel-Chapelon F., Agnoli C., Tumino R., Masala G., Mattiello A., Ricceri F., Travier N., Amiano P., Ardanaz E., Chirlaque M.D., Sanchez M.J., Rodriguez L., Nilsson L.M., Johansson I., Hedblad B., Rosvall M., Lund E., Braaten T., Naska A., Orfanos P., Trichopoulou A., van den Berg S., Bueno de Mesquita H.B., Bergmann M.M., Steffen A., Kaaks R., Teucher B., Wareham N.J., Khaw K.T., Crowe F.L., Illner A.K., Slimani N., Gallo V., Mouw T., Norat T., Peeters P.H. Eur J Clin Nutr 2012; 66(8):957-63
The associations of advanced glycation end products and its soluble receptor with pancreatic cancer risk: A case-control study within the prospective EPIC cohort Grote V.A., Nieters A., Kaaks R., Tjonneland A., Roswall N., Overvad K., Skielbo Nielsen M.R., Clavel Chapelon F., Boutron-Ruault M.C., Racine A., Teucher B., Lukanova A., Boeing H., Drogan D., Trichopoulou A., Trichopoulos D., Lagiou P., Palli D., Sieri S., Tumino R., Vineis P., Mattiello S., Suarez M.V.A., Duell E.J., Sanchez M.J., Dorronsoro M., Castano J.M.H., Barricarte A., Jeurnink S.M., Peeters P.H.M., Sund M., Ye W., Regner S., Lindkvist B., Khaw K.T., Wareham N., Allen N.E., Crowe F.L., Fedirko V., Jenab M., Romaguera D., Siddiq A., Bueno de Mesquita H.B., Rohrmann S. Cancer Epidemiol Biomarkers 2012; 21(4):619-28
The EMAEuropean Medicines Agency quality guideline on the pharmaceutical development of medicines for paediatric use van Riet-Nales D.A., Wang S., Saint-Raymond A., Robert J.L. Int J Pharm 2012; 435(2):132-4
The outcomes of pregnancy in women exposed to the new macrolides in the first trimester: a prospective, multicentre, observational study Bar-Oz B., Weber-Schoendorfer C., Berlin M., Clementi M., di Gianantonio E., de Vries L., de Santis M., Merlob P., Stahl B., Eleftheriou G., Manáková E., Hubicková-Heringová L., Youngster I., Berkovitch M. Drug Saf 2012; 35(7):589-98
The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct study Patel P.S., Forouhi N.G., Kuijsten A., Schulze M.B., van Woudenbergh G.J., Ardanaz E., Amiano P., Arriola L., Balkau B., Barricarte A., Beulens J.W.J., Boeing H., Buijsse B., Crowe F.L., de Lauzon-Guillan B., Fagherazzi G., Franks P.W., Gonzalez C., Grioni S., Halkjaer J., Huerta J.M., Key T.J., Kuhn T., Masala G., Nilsson P., Overvad K., Panico A., Quiros J.R., Rolandsson O., Sacerdote C., Sanchez M.J., Schmidt E.B., Slimani N., Spijkerman A.M.W., Teucher B., Tjonneland A., Tormo M.J., Tumino R., van der A D.L., van der Schouw Y.T., Sharp S.J., Langenberg C., Feskens E.J.M., Riboli E., Wareham N.J. Am J Clin Nutr 2012; 95(6):1445-53
The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans Blaauboer B.J., Boekelheide K., Clewell H.J., Daneshian M., Dingemans M.M.L., Goldberg A.M., Heneweer M., Jaworska J., Kramer N.I., Leist M., Seibert H., Testai E., Vandebriel R.J., Yager J.D., Zurlo J. Altex 2012; 29(4):411-25
Tissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure study Geraets L., Oomen A.G., Schroeter J.D., Coleman V.A., Cassee F.R. Toxicol Sci 2012; 127(2):463-73
Total and high-molecular weight adiponectin and risk of colorectal cancer: The European prospective investigation into cancer and nutrition study Aleksandrova K., Boeing H., Jenab M., Bueno de Mesquita H.B., Jansen E., van Duijnhoven F.J.B., Fedirko V., Rinaldi S., Romieu I., Riboli E., Romaguera D.., Westphal S., Overvad K., et.al. Carcinogenesis 2012; 33(6):1211-8
Towards a decade of detecting new analogues of sildenafil, tadalafil and vardenafil in food supplements: a history, analytical aspects and health risks Venhuis B.J., de Kaste D. J Pharm Biomed Anal 2012; 69:196-208
Toxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns Hochstenbach K., van Leeuwen D.M., Gmuender H., Gottschalk R.W., Stolevik S.B., Nygaard U.C., Lovik M., Granum B., Namork E., Meltzer H.M., Kleinjans J.C., van Delft J.H.M., van Loveren H. Toxicol Sci 2012; 129(2):315-24
Transcriptome analysis of the human T lymphocyte cell line Jurkat and human peripheral blood mononuclear cells exposed to deoxynivalenol (DON): new mechanistic insights Katika M.R., Hendriksen P.J.M., Shao J., van Loveren H., Peijnenburg A. Toxicol Appl Pharmacol 2012; 264(1):51-64
Transcriptomic analysis of neurulation and early organogenesis in rat embryos: an in vivo and ex vivo comparison Robinson J.F., Verhoef A., Piersma A.H. Toxicol Sci 2012; 126(1):255-66
Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural Embryonic Stem Cell Test (ESTn) Theunissen P.T., Robinson J.F., Pennings J.L.A., de Jong E., Claessen S.M.H., Kleinjans J.C.S., Piersma A.H. Toxicol Sci 2012; 125(2):430-8
Transcriptomic fingerprints in human peripheral blood mononuclear cells indicative of genotoxic and non-genotoxic carcinogenic exposure Hochstenbach K., van Leeuwen D.M., Gottschalk R.W., Gmuender H., Stolevik S.B., Nygaard U.C., Lovik M., Granum B., Namork E., van Loveren H., van Delft J.H.M. Mutat Res 2012; 746(2):124-34
Transcriptomics analysis of primary mouse thymocytes exposed to bis(tri-n-butyltin)dioxide (TBTO) van Kol S.W.M., Hendriksen P.J.M., van Loveren H., Peijnenburg A. Toxicology 2012; 296(1-3):37-47
Triazole induced concentration-related gene signatures in rat whole embryo culture Robinson J.F., Tonk E.C.M., Verhoef A., Piersma A.H. Reprod Toxicol 2012; 34(2):275-83
Triazole-induced gene expression changes in the zebrafish embryo Hermsen S.A.B., Pronk T.E., van den Brandhof E.J., van der Ven L.T.M., Piersma A.H. Reprod Toxicol 2012; 34(2):216-24
Updated folate data in the Dutch Food Composition Database and implications for intake estimates Westenbrink S., Jansen-van der Vliet M., van Rossum C. Food Nutr Res 2012; 56(1):1-7
Use of statins is associated with an increased risk of rheumatoid arthritis de Jong H.J.I., Klungel O.H., van Dijk L., Vandebriel R.J., Leufkens H.G.M., van der Laan J.W., Tervaert J.W., van Loveren H. Ann Rheum Dis 2012; 71(5):648-54
Validation of alternative methods for toxicological hazard assessment: issues and challenges Piersma A.H. In: Seidle T, Spielmann H, eds. Alternative testing strategies. Progress report 2012 & AXLR8-3 workshop report on a 'Roadmap to Next Generation Safety Testing Under Horizon 2020'. AXLR8 Consortium, 2012;227-32
Variety in vegetable and fruit consumption and the risk of gastric and esophageal cancer in the European prospective investigation into cancer and nutrition Jeurnink S.M., Buchner F.L., Bueno de Mesquita H.B., Siersema P.D., Boshuizen H.C., Numans M.E., Dahm C.C., Overvad K., Tjonneland A., Roswall N., Clavel Chapelon F., Boutron-Ruault M.C., Morois S., Kaaks R., Teucher B., Boeing H., Buijsse B., Trichopoulou A., Benetou V., Zylis D., Palli D., Sieri S., Vineis P., Tumino R., Panico S., Ocke M.C., Peeters P.H., Skeie G., Brustad M., Lund E., Sanchez-Cantalejo E., Navarro C., Amiano P., Ardanez E., Quiros J.R., Hallmans G., Johansson I., Lindkvist B., Regner S., Khaw K.T., Wareham N., Key T.J., Slimani N., Norat T., Vergnaud A.C., Romaguera D., Gonzalez C.A. Int J Cancer 2012; 131(6):e963-73
Vitamin D status and oxidative stress markers in the elderly with impaired fasting glucose and type 2 diabetes mellitus Gradinaru D., Borsa C., Ionescu C., Margina D., Jansen E. Aging Clin Exp Res 2012; 24(6):595-602
Vitamin D status partly explains ethnic differences in blood pressure: the 'Surinamese in the Netherlands: study on ethnicity and health' Kohli N.R., van Valkengoed I.G.M., Nicolaou M., Brewster L.M., van der A D.L., Stronks K., Snijder M.B. J Hypertens 2012; 30(8): 1581-7
What it means to be global Roberts R.A., Wallis R., Ren J., van der Laan J.W., Sausen P.J., Slikker W. Toxicol Sci 2012; 127(1):313-4