Dr Don Klinkenberg is interested in understanding infectious disease dynamics at the level of the population. Examples are patterns of incidence or prevalence, variation in infectivity or susceptibility between individuals and groups in the population, and their relation to underlying characteristics of individuals. Understanding and quantitative description of such relations enable a solid foundation for public health advice. Dr Klinkenberg has a particular interest in the use of data describing genetic differences between pathogen isolates from different patients. A biologically correct description (model) of the epidemiologic process and of genetic variation arising during transmission between hosts is essential, as well as a statistically correct link of this model to collected data. He prefers analysis of data by using models that he specifically develops and adjusts for the particular problem that has to be addressed.
Don Klinkenberg did his BSc and MSc at the University of Amsterdam, in Medical Biology. He conducted his PhD research at the Institute of Animal Science and Health in Lelystad, The Netherlands (currently the Central Veterinary Institute), on mathematical modelling of Classical Swine Fever transmission. After his graduation, he worked at the Faculty of Veterinary Medicine of Utrecht University, first as a postdoc and then as a Lecturer. In this position he employed mathematical models and statistics to work on various topics: a high diversity of pathogens, and many different applied and fundamental research questions. At the Center of Infectious Disease Dynamics, Don works on the analysis of infectious disease data using mathematical and statistical methods. His focus is on combining genetic and epidemiological data, and on analysis of outbreaks.