During an infectious disease crisis, it is important to implement appropriate measures in good time. The mayor, chair of the security region, or government minister is responsible for deciding that. The medical specialists in infectious disease control at the Municipal Public Health Services (GGDs) and the National Institute of Public Health and the Environment (RIVM) advise these decision-makers about possible measures. Advisory opinions based on the latest professional knowledge in medicine and epidemiology are urgently needed in this context. The Centre for Infectious Disease Control plays a key role in compiling relevant knowledge. To streamline this process, the CIb has a structure for scaling up response.