Titanium dioxide is used as a white pigment in a variety of foodstuffs including candy, coffee creamer, baking and cake decorations, and white sauces. It is added in the form of food additive E171. A small fraction of the poorly soluble titanium dioxide particles consists of nanoparticles. To enable a proper assessment of the potential health risks of titanium dioxide nanoparticles in food products, it is important to obtain further information on its uptake in the body, potential accumulation in tissues, and the hazard potential. In collaboration with others, RIVM is examining the potential health risks of titanium dioxide in foods.