For more than 100 years, RIVMNational Institute for Public Health and the Environment has been promoting public health and safeguarding a healthy and safe environment. We have a central role in infectious disease control, national prevention and population screening programmes and monitoring our population’s health and the state of our environment. We support citizens, professionals and national and local authorities in the challenge of keeping ourselves and our environment healthy, safe and sustainable. Our ambition is to be a trusted advisor using independent research as the basis for our advisory work. Below we present some of the global challenges we work on and elaborate on our tasks and international activities.