In the next few years, an increasing number of women who were previously vaccinated will join the cervical screening programme. Among these women, the risk of cervical cancer and high-grade abnormalities is expected to significantly decrease. To maintain a balance between the costs, burdens, and benefits of the screening programme, it may be desirable to reduce the screening intensity for vaccinated women or for cohorts in which both vaccinated and unvaccinated women participate.
In 2025, Erasmus University Medical Center and Amsterdam University Medical Center conducted an in-depth analysis of the impact of adjusting one or more rounds of the screening schedule (up to age 45) in partially vaccinated cohorts, commissioned by the National Institute for Public Health and the Environment (RIVM). A summary of this analysis can be downloaded below.