For certain substances, the establishment of a probit function is considered to be of general interest, for instance because the substances are often found in quantitative risk assessments (QRAs). For these substances, the compilation of the substance dossier and the derivation of the probit function are dealt with by the government.

Following is an overview of the substances for which the probit functions will be discussed by the expert panel in the period 2015-2017. The exact division of substances may vary per year, in which case the plan of work will be updated.

In recent years, several dozens of probit functions have been evaluated by the expert panel, and consequence analyses carried out for the substances concerned.

Afterwards, the methodology for the derivation of probit functions has been modified, also as a result of the review by international experts [link to workshop report]. In the coming period, the expert panel will update its previously formulated advice regarding the new probit functions where necessary, to ensure that they comply with the new methodology for the derivation.

How the scarce information is deployed is of crucial importance for the intended scientific assessment. In order to collect information in the form of reactions of interested parties, the plan of work of the expert panel and concept advice are also published. An up-to-date consequence analysis is expected in 2017, when the consequences of the implementation of a new version of Safeti-NL will be studied.