Title Athors Published in:
A comparison of associations with childhood lung function between air pollution exposure assessment methods with and without accounting for time-activity patterns. AM Ntarladima, D Karssenberg, I Vaartjes, DE Grobbee, O Schmitz, M Lu, J Boer, G Koppelman, et al. Environ Res 2021; 202:111710
A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. JL Clasen, AK Heath, H van Puyve , I deI Huybrechts, JY Park, P Ferrari, M Johansson, G Scelo, A Ulvik, O Midttun, PM Ueland, MC Ocke, et.al. Am J Clin Nutr 2021; 114)1):338-47
A cross-European study of informal carers' needs in the context of caring for older people, and their experiences with professionals working in integrated care settings. EA Ambugo, SR de Bruin, L Masana, J Micinnes, N Cayuelas Mateu, TP Hagen, B Arrue Int J Integr Care 2021; 21(3):2
A human biomonitoring (HBM) Global Registry Framework: Further advancement of HBM research following the FAIR principles. MZ Jeddi, A Virgolino, P Fantke, NB Hopf, KS Galea, S Remy, S Viegas, V Mustieles, MF Fernandez, N von Goetz, T Vermeire, J van Klaveren, et.al. Int J Hyg Environ Heatlth 2021; 238:113826 
A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment.  S Halappanavar, JD Ede, I Mahapatra, HF Krug, ED Kuempel, I Lynch, RJ Vandebriel, JS Shatkin Nanotoxicology  2021; 15(3):289-310
A new pipeline for the normalization and pooling of metabolomics data. V Viallon, M His, S Rinaldi, M Breeu, rA Gicquiau, B Hemo, nK Overvad, A Tjonneland, AL Rostgaard-Hansen, JA Rothwell, WMM Verschure, nP Engelfriet, et.al. Metabolites 2021; 11(9):631
A psychological network approach to attitudes and preventive behaviors during pandemics: a COVID-19 study in the United Kingdom and the Netherlands. M Chambon, J Dalege, JE Elberse, F van Harreveld Social Psycholog Personal Sci 2021; 13(1) 233–245
A randomized controlled trial comparing community lifestyle interventions to improve adherence to diet and physical activity recommendations: the VitalUM study. HM van Keulen, G van Breukelen, H de Vries, J Brug, I Mesters Eur J Epidemiol 2021; 26(3):345-60
A realistic transfer method reveals low risk of SARS-CoV-2 transmission via contaminated euro coins and banknotes. D Todt, TL Meister, B Tamele, J Howes, P Paulmann, J Schijven, et al. iScience 2021; 24(8):102908
A scoping review of alternative payment models in maternity care: insights in key design elements and effects on health and spending. EF de Vries, ZTM Scheefhals, M de Bruin-Koostra, CA Baan, JN Struijs Int J Integr Care 2021; 21(2):6
A single dose of doxycycline after an Ixodes ricinus tick bite to prevent Lyme borreliosis: an open-label randomized controlled trial. MG Harm, A Hofhuis, H Sprong, SC Bennema, JA Ferreira, M Fonville, A Docters van Leeuwen, WJJ Assendelft, HCPM van Weert, W van Pelt, CC van den Wijngaard J Infect 2021; 82(1):98-104
A systematic review and meta-analysis of validation studies performed on dietary record apps. L Zhang, A Misir, H Boshuizen, M Ocke Adv Nutr 2021; 12(6):2321-2332
A widening gap between boys and girls in musculoskeletal complaints, while growing up from age 11 to age 20 - The PIAMA Birth Cohort Study HSJ Picavet, U Gehring, A van Haselen, GH Koppelman, S Vader, A Wijga, et al. Eur J Pain 2021;  25(4):902-12
Adherence to dietary guidelines and cognitive decline from middle age: the Doetinchem Cohort Study. ACJ Nooyens, B Yildiz, LG Hendriks, S Bass, MPJ van Boxtel, HJS Picavet, JMA Boer, WMM Verschuren Am J Clin Nutr 2021; 114(3):871-81
Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview M Vrijheid, X Basagaña, JR Gonzalez, VWV Jaddoe, G Jensen, HC Keun, EVS Hessel, JD van Klaveren, et al. Environ Epidemiol 2021 Oct 1;5(5):e166
Adverse generational changes in obesity development converge at midlife without increased cardiometabolic risk. D Ibi , ML Rietman, HSJ Picavet, JB van Klinken, K Willems van Dijk, MET Dollé, WMM Verschuren Obesity 2021; 29(11):1925-38 
Age at menopause and risk of ischemic and hemorrhagic stroke. SJGC Welten, NC Onland-Moret, JMA Boer, WMM Verschuren, YT van der Schouw Stroke 2021; 52(8):2583-91
Age, sex and BMI influence on copper, zinc and their major serum carrier proteins in a large European population including Nonagenarian Offspring from MARK-AGE study. F Piacenza, R Giacconi, L Costarelli, A Basso, A Burkle, MET Dollé, E Jansen, et al. J Gerontol A Biol Sci Med Sci 2021; 76(12):2097-2106 
Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study. MG Bacalini, A Reale, M Malavolta, F Ciccarone, M Moreno-Villanueva, MET Dollé, E Jansen, et al. Geroscience 2021; 43(3):1283-302
Air pollution and IgE sensitization in four European birth cohorts - the MeDALL project E Melén, M Standl, U Gehring, H Altug, JM Anto, D Berdel, A Bergstrom, J Bousquet, A Wijga, et al. J Allergy Clin Immunol 2021; 147(2):713-22 
Alternatieve bekostigingsmodellen geboortezorg onder de loep genomen E de Vries, JN Struijs, C Baan Ned Tijdschr Obstetrie Gynecologie 2021: 134
An adverse outcome pathway on the disruption of retinoic acid metabolism leading to developmental craniofacial defects. E Menegola, CHJ Veltman, M Battistoni, F di Renzo, A Moretto, F Metruccio, LTM van der Ven, M Luijten, et al. Toxicology 2021; 458:152843
An ex vivo study in the dual-side perfused cotyledon.  L Schakenraad, MJ van Es, JJ Meerman, PHH van den Broek, H van Hove, J van Drongelen, GAM Eliesen, FGM Russell, R Greupink Placenta 2021; 104:220-231
An integrated approach to testing and assessment of high aspect ratio nanomaterials and its application for grouping based on a common mesothelioma hazard. F Murphy, S Dekkers, H Braakhuis, L Ma-Hock, H Johnston, G Janers, L di Cristo, AG Oomen, et al. NanoImpact 2021; 22:100314
An integrated approach to testing and assessment to support grouping and read-across of nanomaterials after inhalation exposure. HM Braakhuis, F Murphy, L Ma-Hock, S Dekkers, J Keller, AG Oomen, V Stone Appl Vitro Toxicol 2021; 7(3):112-28
An inventory of national surveillance systems assessing physical activity, sedentary behaviour and sport participation of adults in the European Union M Soric, K Meh, P Rocha, W Wendel-Vos, Aden Hollander, G Jurak BMC Public Health 2021; 21(1):1797
An ontology for developmental processes and toxicities of neural tube closure.  HJ Heusinkveld, YCM Staal, NC Baker, G Daston, TB Knudsen, A Piersma Reprod Toxicol 2021; 99:160-7
Anti-Müllerian hormone levels and risk of cancer in women. RMG Verdiesen, CH van Gils, RK Stellato, SMM Verschuren, FJM Broekmans AC de Kat, YT van der Schouw, NC Onland-Moret Maturitas 2021; 143:216-22
Anti-Müllerian hormone levels and risk of type 2 diabetes in women.    RMG Verdiesen, NC Onland-Moret, CH van Gils, RK Stellato, AMW Spijkerman, HSJ Picavet, FJM Borekmans, WMM Verschuren, YT van der Schouw Diabetologia 2021; 64:375-84 
Applicability of organ-on-chip systems in toxicology and pharmacology. MR Schneider, M Oelgeschläger, T Burgdorf, P van Meer, P Theunissen, AS Kienhuis, AH Piersma, RJ Vandebriel Crit Rev Toxicol 2021; 51(6):540-554
Assessing prevalence of inadequacy and excessive iodine intake: misinterpretation is lying in ambush.  J Verkaik-Kloosterman, M de Jong, M Ocke Am J Obstet Gynecol 2021; 224(4):418
Assessment of serum total 25-hydroxyvitamin D assay commutability of Standard Reference Materials and College of American Pathologists accuracy-based vitamin D (ABVD) scheme and vitamin D external quality assessment scheme (DEQAS) materials: vitamin D sta JE Camara , SA Wise, AN Hoofnagle, EL Williams, GD Carter, J Jones, CQ Burdette, EHJM Jansen, net al. Anal Bioanal Chem 2021 ; 413(20):5067-84
Assessment of the endocrine disrupting properties of bisphenol AF: a case study applying the European regulatory criteria and guidance. L Escriva, J Ziliacus, E Hessel, A Beronius Environ Health 2021; 20(1):48
Association of cycling with all-cause and cardiovascular disease mortality among persons with diabetes: the European prospective investigation into cancer and nutrition (EPIC) study. M Ried-Larsen, MG Rasmussen, K Blond, TF Overvad, K Overvad, K Steindorf, V Katzke, JLM Andersen, WMM Verschuren, et al. JAMA Intern Med 2021; 181(9):1196-1205
Association of daily physical activity and sedentary behaviour with protein intake patterns in older adults: A multi-study analysis across five countries. I Lourida, JMA Boer, R Teh, N Kerse, N Mendonca, A Rolleston, S Sette, H Tapanainen, A Turrini, SM Virtanen, M Visser, C Jagger Nutrients 2021; 3(8):2574
Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies. KW Hansen, N Peytz, A Blokstra, SE Bojesen, C Celis-Morales, C Chrusohoou, E Clays, WMM Verschuren, et al. Eur J Prev Cardiol 2021; 181(9):1196-1205 
Associations Between Measures of Social Distancing and Severe Acute Respiratory Syndrome Coronavirus 2 Seropositivity: A Nationwide Population-based Study in the Netherlands ERA Vos, M van Boven, G den Hartog, JA Backer, D Klinkenberg, CCE van Hagen, H Boshuizen, RS van Binnendijk, L Mollema, FRM van der Klis, HE de Melker Clin Infect Dis 2021 ;73(12):2318-2321
Associations of faecal microbiota with influenza-like illness in participants aged 60 years or older: an observational study   The Lancet Healthy Longevity 2021; 2(1):e13–e23
Associations of human colorectal adenoma with serum biomarkers of body iron stores, inflammation and antioxidant protein thiols. B Schottker, X Gao, EHJM Jansen, H Brenner Antioxidants 2021; 10(8):1195
Atmospheric dispersion and transmission of Legionella from wastewater treatment plants: A 6-year case-control study. LC Vermeulen, PS Brandsema, J van de Kassteele, BCJ Bom, HAM Sterk, FJ Sauter, HHJL van den Berg, AM de Roda Husman Int J Hyg Environ Health 2021; 237:113811 
Author correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors. MK Bakker, RAA van der Spek, W van Rheenen, S Morel, R Bourcier, IC Hostetter, WMM Verschuren, et al. Nat Genet 2021; 53(2):254 
Awareness, use and perceptions of cigarillos, heated tobacco products and nicotine pouches: A survey among Dutch adolescents and adults A Havermans , JLA Pennings , I Hegger , JM Elling , H de Vries , CGGM Pauwels , R Talhout Drug Alcohol Depend 2021 ; 229(Pt B):109136
Benzodiazepinen uit het basispakket. Welke aspecten droegen bij aan stopzetten van de vergoeding? AH Rotteveel, MS Lambooij, GA de Wit Ned Tijdschr Geneeskd 2021; 165:D6137
Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008-2020. C Ventura, B Costa Gomes, A Oberemm, H Louro, P Huuskonen, V Mustieles, MF Hernandez, A Ndaw, M Mengelers, M Luijten, C Gundacker, MJ Silva Environ Res 2021; 197:110998
Biomarkers of Frailty - Explorative research with a multi-domain approach ML Rietman Utrecht: Universiteit Utrecht, 2021
Biowaiver monographs for immediate release solid oral dosage forms: metformin hydrochloride. M Metry, Y Shu, B Abrahamsson, R Christofoletti, JB Dressman, DW Groot, A Parr, et al. J Pharm Sci 2021; 110(4): 1513-26
Blood lipids-related dietary patterns derived from reduced rank regression are associated with incident type 2 diabetes. MJ Duan, LH Dekker, JJ Carrero, G Navis Clin Nutr 2021; 40(7):4712-9
BMI trajectories after primary school-based lifestyle intervention: Unravelling an uncertain future. A mixed methods study. M Oosteroff, S Jolani, D de Bruijn-Geraets, A van Giessen, H Bosma, OCP van Schayk, MA Joore Prev Med Rep 2021; 21:101314
Both non-smoking youth and smoking adults like sweet and minty e-liquid flavors more than tobacco flavor. EJZ Krüsemann, L van Tiel, JLA Pennings, W Vaessen, K de Graaf, R Talhout, S Boesveldt Chem Senses 2021; 46:bjab009
Breast milk n-3 long-chain polyunsaturated fatty acids and blood pressure: an individual participant meta-analysis. L van Rossem, HA Smit, M Armand, JY Bernard, H Bisgaard, K Bonnelykke, S Bruun, AH Wijga, et al. Eur J Nutr 2021; 60(2):989-98
Can healthy and sustainable dietary patterns that fit within current dutch food habits be identified? SN Heerschop, S Biesbroek, EHM Temme,MC Ocke Nutrients 2021; 13(4):1176
Cell differentiation in the cardiac embryonic stem cell test (ESTc) is influenced by the oxygen tension in its underlying embryonic stem cell culture RH Mennen, VC de Leeuw, AH Piersma Toxicol in Vitro 2021;77:105247
Cell differentiation in the cardiac embryonic stem cell test (ESTc) is influenced by the oxygen tension in its underlying embryonic stem cell culture. RH Mennen, VC de Leeuw, AH Piersma Toxicol in Vitro 2021; 77:105247 
Circadian rhythm and time-of-day-effects of (anti)oxidant biomarkers for epidemiological studies. T Ruskovska, P Beekhof, N Velickova, N Kamcev, E Jansen Free Radic Res 2021; 55(7):792-8
Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries. G Berbers, P van Gageldonk, J van de Kassteele, U Wiedermann, I Desombere, T Dalby, J Toubiana, S Tsiodras, IP Ferencz, et al. Nat Commun 2021; 12(1):2871
Clients' perspectives on the quality of counseling for prenatal anomaly screening. A comparison between 2011 and 2019. L Martin, JT Gitsels-van der Wal, M Hitzert, J Henrichs Patient Educ Couns 2021; 104(7):1796-805
Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study JE Laine, I Huybrechts, MJ Gunter, P Ferrari, E Weiderpass, K Tsilidis, EHM Temme, JMA Boer, et al. Lancet Planet Health 2021; 5(11):e786-e796
Comment on "External validation of the core obesity model to assess the cost-effectiveness of weight management interventions".    BLT Ramaekers, B Wijnen, N Armstrong, S Petersohn, T Feenstra, J Wang, MA Joore Pharmacoeconomics 2021; 39:133-5 
Comprehensive overview of common e-liquid ingredients and how they can be used to predict an e-liquid's flavour category. EJZ Krüsemann, A Havermans, JLA Pennings, K de Graaf, S Boesveldt, R Talhout Tob Control 2021; 30(2):185-91
Conceptual model for the evaluation of attractiveness, addictiveness and toxicity of tobacco and related products: The example of JUUL e-cigarettes Y Staal, A Havermans, L van Nierop, W Visser, S Wijnhoven, W Bil, R Talhout Regul Toxicol Pharmacol 2021; 127:1050771
Correction to: Adherence to a food group-based dietary guideline and incidence of prediabetes and type 2 diabetes. NR den Braver, F Ruttes, ALJK van der Spek, D Ibi, M Looman, A Geelen, P Elders, AA van der Heiiden, J Brug, J Lakerveld, et al. Eur J Nutr 2021; 60(1):555-556
Corrigendum to 'Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom'. P Versteegen, MV Pinto, AM Barkoff, PGM Gageldonk, J van de Kassteele, MA van Houten, EAM Sanders, AM Buisman, GAM Berbers, et al. EBioMedicine 2021; 68:103420
Corrigendum: Adrenoleukodystrophy newborn screening in the Netherlands (SCAN study): The X-factor. RW Barendsen, IME Dijkstra, WF Visser, M Alders, J Bliek, MJ Bouva, E Elsinghorst, AGM van Gorp, et al. Front Cell Dev Biol 2021; 9:631655
Cost of childhood acute otitis media in primary care in the Netherlands: economic analysis alongside a cluster randomised controlled trial. RT van Uum, RP Venekamp, CTB Pasman, GA de Wit, A Sjoukes, AC van der Pol, RAMJ Damoiseaux, AGM Schilder BMC Health Serv Res 2021; 21(1):193
Cost-effectiveness of a stepwise cardiometabolic disease prevention program: results of a randomized controlled trial in primary care. DM Stol, EAB Over, IF Badenbroek, M Hollander, MMJ Nielen, RA Kraaijenhagen, FG Schellevis, MJ de Wit, GA de Wit BMC Med 2021; 19(1):57
Costs of a clinical pathway with point-of-care testing during influenza epidemic in a Dutch hospital.    SD Marbus, NC Onland-Moret, CH van Gils, RK Stellato, AMW Spijkerman, HSJ Picavet, FJM Broekmans, WMM Verschuren, YT van der Schouw Influenza Other Respir Viruses 2021; 15(2):202-5
Cross-national comparisons of health indicators require standardized definitions and common data sources H Tolonen, J Reinikainen, P Koponen, H Elonheimo, L Palmieri, MJ Tijhuis Arch Public Health 2021;79(1):208
Current challenges in the detection and analysis of falsified medicines. IME 't Bakker-Hart, D Ohana, BJ Venhuis J Pharmaceut Biomed Anal 2021; 197:113498 
Determinants of HPV-vaccination uptake and subgroups with a lower uptake in the Netherlands. AC de MunterTM Schurink-van 't Klooste (rivm), rA van Lier (rivm)'R Akkermans , HE de Melker (rivm), WLM Ruijs (rivm) BMC Public Health 2021; 21(1):1848
Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease: The EU European Union (European Union) EXPANSE project. J Vlaanderen, K de Hoogh, G Hoek, A Peters, N Probst-Hensch, A Scalbert, E Melen, C Tone, GA de Wit, et al. Environ Epidemiol 2021; 5(4):e162
Development of national physical activity recommendations in 18 EU member states: a comparison of methodologies and the use of evidence. A Tcymbal, P Gelius, K Abu-Omar, C Foster, S Whiting, R Mendes, S Titze, TE Dorner, W Wendel-Vos, et al. BMJ Open 2021; 11(4):e041710
Developmental neurotoxicity of environmentally relevant pharmaceuticals and mixtures thereof in a Zebrafish embryo behavioural test. A Atzei, I Jense, EP Zwart, J Legradi, BJ Venhuis, LTM van der Ven, HJ Heusinkveld, EVS Hessel Int J Environ Res Public Health 2021; 18(13):6717
Die-off of plant pathogenic bacteria in tile drainage and anoxic water from a managed aquifer recharge site. C Eisfeld, JW van der Wolf, BM van Breukelen, G Miedema, J Velstra, JF Schijven Plos One 2021; 16(5):e0250338
Dietary changes among adults in The Netherlands in the period 2007-2010 and 2012-2016. results from two cross-sectional National Food Consumption Surveys. CS Dinnissen, MC Okce, EJM Buurma-Rethans, CTM van Rossum Nutrients 2021; 13(5):1520
Dietary exposure to mycotoxins of 1- and 2-year-old children from a Dutch Total Diet Study AM Pustjens, JJM Castenmiller, JD te Biesebeek, TC de Rijk, RCJ van Dam, PE Boon World Mycotoxin Journal 2021; 15(1):85-97
Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: findings from the EPIC-CVD case-cohort study across nine European countries M Steur, L Johnson, SJ Sharp, F Imamura, I Sluijs, TJ Key JMA Boer , WMM Verschuren  J Am Heart Assoc  2021;e019814
Do e-cigarettes attract youths who are otherwise unlikely to use addictive substances? Cross-sectional analyses of Dutch and Flemish secondary school students TF Martinelli, H de Vries, R Talhout, OCP van Schayk, GE Nagelhout Tob Prev Cessat 2021;7:74
Do low molecular weight antioxidants contribute to the Protection against oxidative damage? The interrelation between oxidative stress and low molecular weight antioxidants based on data from the MARK-AGE study. I Pinchuk, R Kohen, W Stuetz, C Franceschi, M Capri, M Hurme, MET Dollé, EHJM Jansen, et al. Arch Biochem Biophys 2021;713:109061
Documentation of aggregated/compiled values in food composition databases; EuroFIR default to improve harmonization. S Westenbrink, K Presser, M Roe, J Ireland, P Finglas J Food Compos Anal 2021; 101:103968
Dutch shared savings program targeted at primary care: Reduced expenditures in its first year. A Hayen, MJ van den Berg, JN Struijs, GP Westert Health Policy 2021; 125(4):489-94
Dutch trauma system performance: Are injured patients treated at the right place? LM Surms, MLS Driessen, D van Klaveren, HJ ten Duis, GJ Kommer, FW Bloemers, D den Hartog, MJ Edwards, PA Leenhouts, S van Zutphen, et al. Injury 2021; 52(7):1688-96
Early childhood infections and body mass index in adolescence. AC Prins-van Ginkel, AH Wijga, PCJ Bruijning-Verhagen, B Brunekreef, U Gehring, W van der Hoek, GH Koppelman, L van Rossem, MAB van der Sande, HA Smit Int J Obes 2021; 45: 1143-51
Effect of operational strategies on microbial water quality in small scale intermittent water supply systems: The case of Moamba, Mozambique. H van den Berg, MN Quaye, E Nguluve, J Schijven, G Ferrero Int J Hyg Environ Health 2021; 236:113764
Effects of exposure to surrounding green, air pollution and traffic noise with non-accidental and cause-specific mortality in the Dutch national cohort. JO Klompmaker, NAH Janssen, LD Bloemsma, M Marra, E Lebret, U Gehring, G Hoek Environ Health 2021; 20(1):82
Effects of protein and calorie restriction on the metabolism and toxicity profile of irinotecan in cancer patients. FM de Man, RAG van Eerden, GM van Doorn, E Oomen-de Hoop, SLW Koolen, JF Olieman, P de Bruijn, JN Veraart, HK van Halteren, MET Dollé, et al. Clin Pharnacol Ther 2021; 109(5):1304-13
Effects of providing tailored information about e-cigarettes in a web-based smoking cessation intervention: protocol for a randomized controlled trial. JM Eling, R Crutzen, R Talhout, H de Vries JMIR Res Protoc 2021; 10(5):e27088
Episode detection based on personalized intensity of care thresholds: a schizophrenia case study.  SRA Konings, R Bruggeman, E Visser, RA Schoevers, JO Mierau, TL Feenstra Soc Sci Med 2021; 270:113507
Evaluation of nutrient intake and food consumption among Dutch toddlers. E Steenbergen, A Krijger, J Verkaik-Kloosterman, LEM Elstgeest, S ter Borg, KFM Joosten, CTM van Rossum Nutrients 2021; 13(5):1531
Evaluation of nutri-score in relation to dietary guidelines and food reformulation in the Netherlands S Ter Borg, E Steenbergen, IEJ Milder, EHM Temme Nutrients 2021; 13(12): 4536
Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies. A Sofranko, T Wahle, HJ Heusinkveld, B Stahlmecke, M Cronov, D Pijnenburg, R Hilhorst, K Lamann, C Albrecht, RPF Schins Neurotoxicology 2021; 84:155-71
Excess deaths during influenza and coronavirus disease and infection-fatality rate for severe acute respiratory syndrome coronavirus 2, the Netherlands. L van Asten, CN Harmsen, L Stoeldraijer, D Klinkenberg, A Teirlinck, MMA de Lange, A Meijer, J van de Kassteele, AB van Gageldonk-Lafeber, S van den Hof, W van der Hoek Emerg Infect Dis 2021; 27(2):411-20
Expanded neonatal bloodspot screening programmes: an evaluation framework to discuss new conditions with stakeholders. ME Jansen, AW Klein, EC Buitenhuis, W Rodenburg, MC Cornel Front Pediatr 2021; 9:635353
Explaining the association between frailty and mortality in older adults: The mediating role of lifestyle, social, psychological, cognitive, and physical factors. S de Breij, JJM Rijnhart, NA Schuster, ML Rietman Preventive Medicine Reports 2021; 24:101589 
Exploring neurobehaviour in zebrafish embryos as a screening model for addictiveness of substances. A Havermans, EP Zwart, HWJM Cremers, MDM van Schijndel, RS Constant, M Meskovic, JLA Pennings, R Talhout, LTM van der Ven, et al. Toxics 2021; 9(10):250
Exploring Neurobehaviour in Zebrafish Embryos as a Screening
Model for Addictiveness of Substances
  Toxics 2021; 9(10): 250
Exploring the biological domain of the neural embryonic stem cell test (ESTn): morphogenetic regulators, Hox genes and cell types, and their usefulness as biomarkers for embryotoxicity screening. VC de Leeuw, JLA Pennings, EVS Hessel, AH Piersma Toxicology 2021; 454:152735
Exploring the gateway hypothesis of e-cigarettes and tobacco: a prospective replication study among adolescents in the Netherlands and Flanders. T Martinelli, MJJM Candel, H de Vries, R Talhout, V Knapen, CP van Schayk, GE Nagelhout Tob Control 2021; tobaccocontrol.2021-056528
Fecal microbiota transplantation influences procarcinogenic Escherichia coli in recipient recurrent Clostridioides difficile patients. S Nooij, QR Ducarmon, JFJ Laros, RD Zwittink, JM Norman, WK Smits, EJ Kuijper, et al.

Gastroenterology 2021; 161(4):1218-1228.e5
Gene regulation by morpholines and piperidines in the cardiac embryonic stem cell test RH Mennen, N Hallmark, M Pallardy, R Bars, H Tinwell, AH Piersma, et al Toxicol Appl Pharmacol 2021 ; 433:115781
Genetic microbial source tracking support QMRA Modeling for a riverine wetland drinking water resource. J Derx, K Demeter, R Linke, S Cervero-Arago, G Lindner, G Stalder, J Schijven, et al. Front Microbiol 2021; 12:668778
Green space, air pollution, traffic noise and saliva cortisol in children: The PIAMA study. LD Bloemsa, AH Wijga, JO Klompmaker, G Hoek, NAH Janssen, M Oldenwening, GH Koppelman, E Lebret, B Brunekreef, U Gehring Environ Epidemiol 2021; 5(2):e141
Grumpy or depressed? Disentangling typically developing adolescent mood from prodromal depression using experience sampling methods. E Dietvorst, M Hiemstra D Maciejewski, E van Boekel, T ter Bogt, M Hillegers, L Keijsers J Adolesc 2021; 88:25-35
Guidance Document on Scientific criteria for groupingchemicals into assessment groups for human riskassessment of combined exposure to multiple chemicals EFSA Scientic Committee, SJ More, V Bampidis, D Benford, C Bragard, JD te Biesebeek, et al. EFSA Journal 2021; 19(12):e7033
Headache in girls and boys growing up from age 11 to 20 years: the PIAMA birth cohort study.    AH Wijga, U Gehring, EM van de Putte, G Koppelman, S Vader, RJH Schmits, JC van der Wouden, HSJ Picavet Pain 2021; 162(5):1449-56
How to recruit inactive residents for lifestyle interventions: Participants' characteristics based on various recruitment strategies. E Smit, K Leenaars, A Wagemakers, K van der Velden, G Molleman Health Promot Intern 2021; 36(4):989-99
Identified micro-organisms in hospitalized community-acquired pneumonia patients living near goat and poultry farms. I Roof; AB van Gageldonk-Lafeber; TP Zomer; YM Vermeeren; PC Wever; W van der Hoek Pneumonia  2021;13(1):13
Identifying and delineating the type 2 diabetes population in the Netherlands using an all-payer claims database: characteristics, healthcare utilisation and expenditures. RJ Geurten; MJ Elissen; HJG Bilo; JN Struijs; C van Tilburg; D Ruwaard BMJ Open 2021;11(12):e049487
Impact analysis of rotavirus vaccination in various geographic regions in Western Europe. JDM Verberk, ,JAP van DongenJ van de Kassteele, NJ AndrewsRD van Gaale ,SJM Hahné ,H Vennema, HE de Melker, P Bruijning-Verhagen , et al. Vaccine 2021 ; 39(45):6671-81
Improving the analysis of E-cigarette emissions: detecting human “Dry Puff” conditions in a laboratory as validated by a panel of experienced vapers WF Visser, EJZ Krüsemann, WNM Klerx  K Boer, N Weibolt, R Talhout Int J Environ Res Public Health 2022 ; 18(21):11520
In uitvoering. Een analyse van het op statushouders gerichte beleid en wat er nodig is om dit beleid te verbeteren Dagevos J, Schans D, Uiters E Den Haag: Sociaal en Cultureel Planbureau, 2021
In vitro characterization of the innate immune pathways engaged by live and inactivated tick-borne Encephalitis virus. A Signorazzi, JLA Pennings, MP Etna, M Noya, EM Coccia, A Huckriede Vaccines 2021; 9(6):664
Inductively coupled plasma-mass spectrometry in biodistribution studies of (engineered) nanoparticles P Krystek, CM Cirtiu, H Braakhuis, M Park, W de Jong Atomic Spectrosc 2021
Informing parents about newborn screening: a European Comparison Study. A Ijzebrink, T van Dijk, V Frankova, G Loeber, V Kozich, L Henneman, M Jansen Int J Neonatal Screen 2021; 7(1):13
It's all the other stuff!' How smokers understand (and misunderstand) chemicals in cigarettes and cigarette smoke   Public Underst Sci 2021; 30(6):777-796
It's like juggling, constantly trying to keep all balls in the air: a qualitative study of the support needs of working caregivers taking care of older adults. EE Vos, SR de Bruin, AJ van der Beek, KI Proper Int J Environ Res Public Health 2021; 18(11):5701
Large health disparities in cardiovascular death in men and women, by ethnicity and socioeconomic status in an urban based population cohort. JM Kist, GWG Smit, ATA Mairuhu, JN Struijs, RC Vos, PG van Peet, HMM Vos, ED Beishuizen, YWJ Sijpkens, RHH Groenwold, Numans ME,  EClinicalMedicine 2021; 40:101120
LEDA, the branded food database in the Netherlands: Data challenges and opportunities. S Westenbrink, WP van der Vossen-Wijmenga, I Toxopeus, I Milder, M Ocke J Food Composition Anal 2021; 102:104044
Levensverwachting en sterfte van mensen met diabetes mellitus Leemrijse C, Poos R, Hilderink H, Heins M, Nielen M, Korevaar J Utrecht: NIVEL, 2021
Lifestyle after colorectal cancer diagnosis in relation to recurrence and all-cause mortality M van Zutphen, HC Boshuizen, MF Kenkhuis, E Wesselink, AJMR Geijsen The American journal of clinical nutrition 113 (6), 1447-1457
Lifestyle correlates of eight breast cancer-related metabolites: a cross-sectional study within the EPIC cohort M His, V Viallon, L Dossus, JA Schmidt, RC Travis, JMA Boer, et al. BMC Med 2021 ;19(1):312
Longitudinal associations of substance use risk profiles with the use of alternative tobacco products and conventional smoking among adolescents M Hiemstra, A Rozema, M Jansen, H van Oers, J Mathijssen Int J Environ Res Public Health 2021; 18(24):13248 
Longitudinal Associations of Substance Use Risk Profiles with the Use of Alternative Tobacco Products and Conventional Smoking among Adolescents M Hiemstra, A Rozema, M Jansen, H van Oers, J Mathijssen Int J Environ Res Public Health 2021 Dec 16;18(24):13248
Long-term effects of smoking on serum concentrations of oxidative stress biomarkers: Results of a large, population-based cohort study. A Abdelraouf Salem, K Trares, M Kohl, E Jansen, H Brenner, B Schottker Environ Res 2021; 204(A):111923
Mapping chronic disease prevalence based on medication use and socio-demographic variables: an application of LASSO on administrative data sources in healthcare in the Netherlands. K Füssenich, HC Boshuizen, MMJ Nielen, E Buskens, TL Feenstra BMC Public Health 2021; 21(1):1039
Measurement and genetic architecture of lifetime depression in the Netherlands as assessed by LIDAS (Lifetime Depression Assessment Self-report). IO Fedko, JJ Hottenga, Q Helmer, H Mbarek, F Hulder, N Amin, HSJ Picavet, WMM Verschuren, et al. Psychol Med 2021; 51: 1345–54
Measuring older peoples' experiences of person-centred coordinated care: experience and methodological reflections from applying a patient reported experience measure in SUSTAIN. J Reynolds, E Gadsby, M Rijken, A Stoop, M Espallarguelles, HM Lloyd, J Close, S de Bruin Int J Integr Care 2021; 21(3):3
Mechanism of Action of TiO2: Recommendations to Reduce Uncertainties Related to Carcinogenic Potential.    Annu Rev Pharmacol Toxicol 2021; 61:203-23
Mental well-being and general health in adolescents with asthma: the prevention and incidence of asthma and mite allergy birth cohort study. SEI van der Laan, MIA de Hoog, SL Nijhof, U Gehring, JM Vonk, CK van der Ent, AH Wijga J Pediatr 2021; 233:198-205.e2
Met beleid van start. Over de rol van beleid voor ontwikkelingen in de positie en leefsituatie van Syrische statushouders W Huijnk, J Dagevos, M Djundeva, D Schans, E Uiters, A Ruijsbroek, M de Mooij Den Haag; Sociaal en Cultureel Planbureau, 2021
Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation. B Halamoda-Kenzaoui, RJ Vandebriel, A Howarth, M Siccardi, CAW David, NJ Liptrott, et al. J Control Release 2021; 336:192-206
Methodology and implementation of the WHO European Childhood Obesity Surveillance Initiative (COSI) J Breda, K McColl, M Buoncristiano, J Williams. S Abdrakhmanova, JMA Boer, et.al Obes Rev 2021;22(supp 6):e13215
Microbiome in blood samples from the general population recruited in the MARK-AGE project: a pilot study. P d'Aguila, R Giacconi, M Malavolta, F Piacenza, A  Bürkle, M Moreno-Villanueva, MET Dollé, E Jansen, et al. Front Microbiol 2021; 12:707515
Model development for evidence-based prioritisation of policy action on emerging chemical and microbial drinking water risks J Hartmann, JC Chacon-Hurtado, E Verbruggen, J Schijven, E Rorije, S Wuijts, AM de Roda Husman, JP van der Hoek, L Scholten J Environ Manage 2021; 295:112902
Modelling the interplay of future changes and wastewater management measures on the microbiological river water quality considering safe drinking water production. K Demeter, J Derx, J Komma, J Parajka, J Schijven, R Sommer, S Cervero-Arago,  G Lindner, CM Zoufal-Hruza, R Linke, et al. Sci Total Environ 2021; 768:144278 
Modelling the renal excretion of the mycotoxin deoxynivalenol in humans in an everyday situation. AD van den Brand, R Hoogenveen, MJB Mengelers, M ZeilmakerG, S Eriksen, S Uhlig, AL Brantsæter, HAAM Dirven, T Husøy Toxins 2021; 13(10):675 
Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test. RH Mennen, N Hallmark, M Pallardy, R Bars, H Tinwell, AH Piersma  Toxicol Rep 2021; 8:1513-20
More than cost-effectiveness? Applying a second-stage filter to improve policy decision making. K Kan, F Jorg, J Lokkerbol. C Mihalopolus, E Buskens, RA Schoever, TL Feenstra Health Expect 2021; 24(4):1413-23
Mortality review as a tool to assess the contribution of healthcare-associated infections to death: results of a multicentre validity and reproducibility study, 11 European Union countries, 2017 to 2018. T van der Kooi, A Lepape, P Astagneau, C Suetens, MA Nicolaie, S de Greeff, I Lozoraitiene, J Czepiel, EJ Kuijper, et al. Euro Surveill 2021; 26(23):pii.2000052
Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts. L Hölzl-Armstrong, S Moody, JE Kucab, EP Zwart, M Bellamri, M Luijten, et al. Food Chem Toxicol 2021; 147:111885
Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts. L Hölzl-Armstrong, JE Kucab, EP Zwart, M Luijten, DH Philips, VM Arit Environ Mol Mutagen 2021; 62(4):252-64 
Nationwide surveillance reveals frequent detection of carbapenemase-producing Enterobacterales in Dutch municipal wastewater. H Blaak, MA Kemper, H de Man, JPG van Leuken, JF Schijven, Mw/J van Passel, H Schmitt, AM de Roda Husman Sci Total Environ 2021; 776:145925 
Nearly 20 000 e-liquids and 250 unique flavour descriptions: an overview of the Dutch market based on information from manufacturers. A Havermans, EJZ  Krüsemann, J Pennings, K de Graaf, S Boesveld, R Talhout Tob Control 2021; 30:57–62
Neighborhood walkability, physical activity and changes in glycemic markers in people with type 2 diabetes: The Hoorn Diabetes Care System cohort. NR den Braver, F Rutters, AJ Wagtendonk, JG Kok, PP Harms, J Brug, JWJ Beulens, J Lakerveld Health Place 2021; 69:102560
Neonatal heel prick screening TSH concentration in the Netherlands as indicator of iodine status. J Verkaik-Kloosterman  Nutr J 2021; 20(1):63
Neonatal screening in Europe revisited: an ISNS perspective on the current state and developments since 2010. JG Loeber, D Platis, RH Zetterstrom, S Almashanu, F Boemer, JR Bonham, P Borde, I Brincat, D Cheillan, E Dekkers, et al. Int J Neonatal Screen 2021; 7(1):15
Neonatal screening in Europe revisited: An ISNS-perspective on the current state and developments since 2010 JG Loeber, D Platis, RH Zetterstrom, PCJI Schielen Med Sci 2021; 37(5):441-56
Next Generation HGVS Nomenclature Checker. M Letter, JK Vis, M Vermaat, JT den Dunnen, PEM Taschner, JFJ Laros Bioinformatics 2021; 37(18):2811-2817
Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and higenamine. PA Cohen, JC Travis, C Vanhee, D Ohana, BJ Venhuis Clin Toxicol 2021; 59(11):975-81
Occupational exposure to hexavalent chromium. Part I. Hazard assessment of non-cancer health effects. EVS Hessel, YCM Staal, AH Piersma, SP den Braver-Sewrad, jJ Ezendam Regul Toxicol Pharmacol 2021; 126:105048 
Occupational exposure to hexavalent chromium. Part II. Hazard assessment of carcinogenic effects. SP den Braver-Sewradj, J van Benthem, YCM Staal, J Ezendam, AH Piersma, EVS Hessel Regul Toxicol Pharmacol 2021; 126:105045
Opinion of the Scientific Committee on consumer safety (SCCS) - final opinion on propylparaben (CAS No 94-13-3, EC No 202-307-7). L Bodin, V Rogiers, U Bernauer, Q Chaudry, PJ Coenraads, M Dusinska, J Ezendam, E Gaffet, S Wijnhoven, et al. Regul Toxicol Pharmacol 2021; 125:105005
Optimal vaccine allocation for COVID-19 in the Netherlands: A data-driven prioritization. F MiuraK; Y Leung; D Klinkenberg; KEC Ainslie; J Wallinga PLoS Comput Biol 2021;17(12):e1009697 
Optimization of an air-liquid interface in vitro cell co-culture model to estimate the hazard of aerosol exposures.   RW He, HM Braakhuis, RJ Vandebriel, YCM Staal, ER Gremmer, PHB Fokkens, C Kemp, J Vermeulen, RHS Westerink, FR Cassee J Aerosol Sci 2021; 152:150703
Options for imaging cellular therapeutics in vivo: a multi-stakeholder perspective. BM Helfer, V Ponomarev, PS Patrick, PJ Blower, A Feitel, GO Fruhwith, MVD Park, et al. Cytotherapy 2021; 23(9):757-73
Overcoming scientific barriers in the transition from in vivo to non-animal batch testing of human and veterinary vaccines. RHGA van den Biggelaa, rMHN Hoefnagel, RJ Vandebrie, lA Sloots, CFM Hendriksen, W van Eden, VPMG Rutten, CA Jansen Expert Rev Vaccines 2021; 20(13):1221-1233 
Overview of national health reporting in the EU and quality criteria for public health reports - results of the Joint Action InfAct M Thissen, S Seeling, P Achterberg, A Fehr, L Palmieri, MJ Tijhuis, B Unim, T Ziese Arch Public Health 2021;79(1):229
Parents' perspectives and societal acceptance of implementation of newborn screening for SCID in the Netherlands.    M Blom, RGM Bredius, ME Jansen, G Weijman, EA Kemper, CL Vermont, IHIM Holink, WH Dik, EHBM Dekkers, PCJI Schielen, et al. J Clin Immunol 2021; 41:99-108
Patient, family and productivity costs of end-stage renal disease in the Netherlands; exposing non-healthcare related costs EF de Vries, J Los, GA de Wit, L Hakkaart-van Roijen BMC Nephrology 2021; 22(1):341
Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients. MP Dent, E Vaillantcourt, RS Thomas, PL Carmichael, G Quadraogo, H Kojma, J Barroso, J Ansell, J Ezendam, et al. Regul Pharmacol Toxicol 2021; 125:105026 
Performance evaluation of handheld Raman spectroscopy for cocaine detection in forensic case samples.    RF Kranenburg, J Verduin, R de Ridder, Y Weeseppel. M Alewijn, M Heerscop, PHJ Keizers, A van Esch, AC van Asten Drug Test Anal 2021; 13(5):1054-67
Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study. RC Slieker, AAWA van der Heijden, MK Siddiqui, M Langendoen-Gort, G Nijpels, R Herings, TL Feenstra, KGM Moons, S Bell, PJ Elders, LM 't Hart, JWJ Beulens BMJ 2021; 374:n2134
Persistence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 in Relation to Symptoms in a Nationwide Prospective Study G den Hartog, ERA VoS, LL van den Hoogen, M van Boven, RM Schepp, G Smits, J van Vliet, L Woudstra, AJ Wijmenga-Monsuur, CCE van Hagen, EAM Sanders, HE de Melker, FRM van der Klis, RS van Binnendijk Clin Infect Dis 2021 ;73(12):2155-2162
Plasma vitamin C and type 2 diabetes: genome-wide association study and Mendelian randomization analysis in European populations.    JS Zheng, J Luan, E Sofianopoulou, F Inamura, ID Stewart, FR Day, M Pietzner, E Wheeler, LA Lotta, TE Gundersen, P Arriano, E Ardanaz, AMW Spijkerman, et al. Diabetes Care 2021; 44(1):98-106
Population-based serology reveals risk factors for RSV infection in children younger than 5 years. SP Andeweg, RM Schepp, J van de Kassteele, L Mollema, GAM Berbers, M van Boven Sci Rep 2021; 11(1):8953
Potential impact of prioritisation methods on the outcome of cumulative exposure assessments of pesticides JD te Biesebeek, M Sam, RC Sprong, G van Donkersgoed, JW Kruisselbrink, WJ Boer, M van Lenthe, H van der Voet, JD van Klaveren EFSA Supporting Publications 2021; 18(4):6559E
Prediction of mortality and major cardiovascular complications in type 2 diabetes: external validation of UKPDS outcomes model version 2 in two European observational cohorts.    E Pagano, SRA Konings, D di Cuonzo, R Rosato, G Bruno, AA van der Heijden, J Beulens, R Slieker, J Leal, TL Feenstra Diabetes Obes Metab 2021; 23(5):1084-1091
Predictors of frailty and vitality in older adults aged 75 years and over: results from the longitudinal aging study Amsterdam. S de Breij, HPJ van Hout, SR de Bruin, NA Schuster, DJH Deeg, M Huisman, EO Hoogendijk Gerontology 2021; 67(1):69-77
Prevalence of persistent symptoms after treatment for lyme borreliosis: A prospective observational cohort study. J Ursinus, HD Vrijmoeth, MG Harms, AD Tulen, H Knoop, SA Gauw, TP Zomer, A Wong, IHM Friesema, YM Vermeeren, LAB Joosten, JW Hovius, BJ Kullberg, CC van den Wijngaard Lancet Reg Health Eur 2021; 6:100142 
Prognostic models for predicting the risk of foot ulcer or amputation in people with type 2 diabetes: a systematic review and external validation study. JWJ Beulen, JS Yauw, PJM Elders, T Feenstra, RC Slieker, KGM Moons, G Nijpels, AA van de Heijden Diabetogia 2021;  64:1550-62
Promoting physical distancing during COVID-19: a systematic approach to compare behavioral interventions. TF Blanken, CC Tanis, FH Nauta, F Dablander, BJH Zijlstra, RRM Bouten, Oostvogel , QHMJ Boersma, MV van der Steenhoven, F van Harreveld, S de Wit, D Borsboom Sci Rep 2021; 11(1):19463
Proposed prospective scenarios for cumulative risk assessment of pesticide residues JD van Klaveren, AD van den Brand, G van Donkersgoed, T van der Velde-Koerts, H van der Voet, JW Kruisselbrink, WJ de Boer, M van Lenthe, C Spring EFSA Supporting Publications 2021; 18(8), 6811E
Protein intake pattern over the day and its association with low total protein intake in Dutch community-dwelling older adults. TH Rooijackers, MC Ocke, LM Hengeveld, M Visser, JM Boer Public Health Nutr 2021; 24(6):1415-27
Proteomic analysis of chicken bone marrow-derived dendritic cells in response to an inactivated IBV + NDV poultry vaccine. RHGA van den Biggelaar, L van de Maas, HD Meiring, JLA Pennings, W van Eden, VPMG Rutten, CA Jansen Sci Rep 2021; 11(1):12666
Proximity to livestock farms and exposure to livestock-related particulate matter are associated with lower probability of medication dispensing for obstructive airway  PM Post, D Houthuijs, HAM Sterk, M Marra, J van de Kassteele, A van Put, LAM Smit, W van der Hoek, E Lebret, I Hogerwerf Int J Hyg Environ Health 2021; 231:113651 
Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses. LA van Tuijl, AC Voogd, A de Graeff, AW Hoogendoorn, AV Ranchor, KY Pan, WMM Verschuren, et al. Brain Behav 2021; 11(10):e2340
Pulmonary toxicity and gene expression changes after short-term inhalation exposure to surface-modified copper oxide nanoparticles. I Gosesn, PM Costa, M Olsson, V Stone, AL Costa, A Brunelli, E Badetti, A Bonetto, BGH Bokkers, WH de Jng, A Williams, S Halappanaver, B Fadeel, FR Cassee NanoImpact 2021; 22:100313
Quantitative microbial risk assessment for airborne transmission of SARS-CoV-2 via breathing, speaking, singing, coughing, and sneezing. J Schijven, LC Vermeulen, A Swart, A Meijer, E Duijzer, AM de Roda Husman Environ Health Perspect 2021; 129(4):47002
Ramadan fasting during pregnancy and health outcomes in offspring: A systematic review VNL Oosterwijk, JM Molenaar, LA van Bilsen, JC Kiefte- De Jong Nutrients 2021;13(10):3450  
Real-World treatment costs and care utilization in patients with major depressive disorder with and without psychiatric comorbidities in specialist mental healthcare. K Kan, J Lokkerbol, F Joerg, E Visser, RA Schoevers, TL Feenstra Pharmacoeconomics 2021; 39(6):721-730
Recommendations to plan a national burden of disease study. R Haneef, J Schmidt, A Gallay, B Devleesschauwer, I Grant, A Rommel, GMA Wyper, H van Oyen, H Hilderink, T Ziese, J  Newton Arch Public Health 2021; 79(1):126
Red blood cell fatty acids and risk of colorectal cancer in The European Prospective Investigation into Cancer and Nutrition (EPIC). J Linseisen, N Grundmann, D Zoller, T Kuhn, EHJM Jansen, V Chajes, et al. Cancer Epidemiol Biomarkers Prev 2021; 30(5):874-85
Regulatory landscape of providing information on newborn screening to parents across Europe.    V Frankova, RO Driscoll, ME Jansen, JG Loeber, V Kozich, J Bonham, P Borde, I Brincat, D Cheillan, E Dekkers, et al. Eur J Hum Genet 2021; 29:67-78
Relationship between primary stroke center volume and time to endovascular thrombectomy in acute ischemic stroke. LCC van Meenen, SJ den Hartog, AE Groot, BJ Emmer, MD Smeekes, A Siegers, GJ Kommer, CBLM Majoie, YBWM Roo, sACGM van Es, et.al. Eur J Neurol 2021; 28(12):4031-4038
Relationship of physical activity at older age with biomarkers of oxidative stress: a large, population-based cohort study. B Schöttker, A Salem, M Schwenk, X Gao, EHJM Jansen, H Brenner Med Sci Sports Exerc 2021; 53(12):2528-2535
Relative validity of MijnEetmeter: a food diary app for self-monitoring of dietary intake. M Ocke, CS Dinnissen, A Stafleu, J de Vries, C van Rossum Nutrients 2021; 13(4):1135
Relevance of In Vitro transcriptomics for In Vivo mode of action assessment. M Luijten, PFK Wackers, E Rorije, JLA Pennings, HJ Heusinkveld Chem Res Toxicol 2021; 34:(2):452-9
Residential exposure to fast-food restaurants and its association with diet quality, overweight and obesity in the Netherlands: a cross-sectional analysis in the EPIC-NL cohort. MC Harbers, JWJ Beulens, JMA Boer, D Karssenberg, JD Mackenbach, F Rutters, I Vaartjes, WMM Verschuren, YT van der Schouw Nutr J 2021; 20(1):56
Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom. P Versteegen, MV Pinto, AM Barkoff, PGM van Gageldonk, J van de Kassteele, MA van Houten, EAM Sanders, R de Groot, GAM Berbers, et al. EBioMedicine 2021; 65:103247
Review of long-term immunogenicity following HPV vaccination: Gaps in current knowledge. J Hoes, H Pasman, TM Schurink-van 't Klooster, FRM van der Klis, R Donken, J Berkhof, HE de Melker Hum Vaccin Immunother 2021; 17(6):626
Risk assessment of components in tobacco smoke and e-cigarette aerosols: a pragmatic choice of dose metrics. PMJ Bos, LG Soeteman-Hernandez, R Talhout Inhal Toxicol 2021; 33(3):81-95
Risk assessment of per- and polyfluoroalkyl substances (PFASs) mixtures: a relative potency factor approach. W Bil, M Zeilmaker, S Fragki, J Lijzen, E Verbruggen, B Bokkers Environ Toxicol Chem 2021; 40(3):859-70
Risk-benefit in food safety and nutrition - Outcome of the 2019 Parma Summer School. H Verhagen, C Alonso-Andicoberry, R Assuncao, F Cavalieri, H Eneroth, J Hoekstra, et al. Food Res Int 2021; 141:110073 
Safer chemicals using less animals: kick-off of the European ONTOX project. M Vinken, E Benfenati, F Busquet, J Castell, DA Clevert, TM de Kok, AH Piersma, et al. Toxicology 2021; 458:152846
Second Tier testing to reduce the number of non-actionable secondary findings and false-positive referrals in newborn screening for severe combined immunodeficiency. M Blom, I Pico-Knijnenburg, S Imholz, L Vissers, J Schulze, J Werner, R Bredius, M van der Burg J Clin Immunol 2021; 41:1762-73 
Second-tier testing for 21-hydroxylase deficiency in the Netherlands; a newborn screening pilot study K Stroek, A Ruiter, A van der Linde, MJ Bouva, et al. J Clin Endocrinol Metab 2021; 106(11):e4487-e4496
Seizing the moment: now is the time for integrated global surveillance of antimicrobial resistance in wastewater environments. A Pruden, PJ Vikesland, BC DavisA, M de Roda Husman Curr Opin Microbiol 2021;64:91-9
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains. L Kananen, L Enroth, J Raitanen, J Jylhava, A Bürkle,, M Moreno-Villanueva, J Bernhardt, O Toussaint, B Grubeck-Loebenstein, M Malavolta, A Basso, F Piacenza, EHJM Jansen, et al. Sci Rep 2021; 11(1):6139
Sex differences in mental health among older adults: investigating time trends and possible risk groups with regard to age, educational level and ethnicity.  LD Sialino, SH van Oostrom, SAH Wijnhoven, S Picavet, WMM Verschuren, M Visser, LA Schaap Aging Ment Health 2021; 25(12):2355-64
Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis.  D Kocevska, TS Lysen, A Dotinga, ME Koopman-Verhoeff, ME Luijk, A Blokstra, J Brug, L Grievink, et al. Nat Hum Behav 2021: 5:113-22
Social jetlag and related risks for human health: A timely review R Caliandro, AA Streng, LWM van Kerkhof, GTJ van der Horst, I Chaves Nutrients 2021; 13(12): 4543
Societal effects are a major factor for the uptake of the coronavirus disease 2019 (COVID-19) digital contact tracing app in the Netherlands. N Mouter, M Collewet, GA de Wit, A Rotteveel, MS Lambooij, R Kessels Value Health 2021; 24(5):658-67
Societal views in the Netherlands on active disinvestment of publicly funded healthcare interventions. AH Rotteveel, RT Reckers-Droog, MS Lambooij, GA de Wit, NJA van Exel Soc Sci Med 2021;272:113708
Socioeconomic differences in healthcare expenditure and utilization in The Netherlands. B Loef, I Meulman, GCM Herber-Gast, GJ Kommer, MA Koopmanschap, AE Kunst, JJ Polder, A Wong, E Uiters BMC Health Serv Res 2021; 21(1):643
SOCRATES-CoMix: a platform for timely and open-source contact mixing data during and in between COVID-19 surges and interventions in over 20 European countries. F Verels, L Hermans, S Vercruysse, A Gimma, P ColettiJ, A Backer, KLM Wong, J Wambua, K van Zandvoort, L Willem, L Bogaardt, et.al. BMC Med 2021; 19(1):254
Substitution among milk and yogurt products and the risk of incident type 2 diabetes in the EPIC-NL cohort. JM Stuber, LET Vissers, WMM Verschuren, JMA Boer, YT van der Schouw, I Sluijs J Human Nutr Diet 2021; 34(1):54-63
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not? S Fragki, H Dirven, T Fletcher, B Grasi-Kraupp, KB Gutzkow, R Hoogenboom, S Kersten, B Lindeman, J Louisse, A Peijnenburg, AH Piersma, M Zeilmaker, M Luijten, et al. Crit Rev Toxicol 2021; 51(2):141-64
Testing behaviour and positivity for SARS-CoV-2 infection: insights from web-based participatory surveillance in the Netherlands SA McDonald, LC Soetens, CMA Schipper, I Friesema, CC van den Wijngaard, A Teirlinck, N Neppelenbroek, S van den Hof, J Wallinga, AJ van Hoek BMJ Open 2021;11(12):e056077
The added value of using the HEPA PAT for physical activity policy monitoring: a four-country comparison. P Gelius, S Messing, S Forberger, J Lakerveld, F Mansergh, W Wendel-Vos, J Zukowska, C Woods Health Res Policy Syst 2021; 19(1):22
The association between depression and oral health related quality of life in people who inject drugs S Abdelsalam, W van den Boom, P Higgs, P Dietze, B Erbas Drug and Alcohol Dependence 2021; 229:109121
The association of the Mediterranean diet with heart failure risk in a Dutch population.    JG Strengers, HM den Ruijter, JMA Boer, FW Asselbergs, WMM Verschuren, UT van der Schouw, I Sluijs Nutr Metab Cardiovasc Dis 2021; 31(1):60-6
The association of vitamin D with survival in colorectal cancer patients depends on antioxidant capacity. D Boakye, L Jansen, B  Schöttker, EHJM Jansen, N Halama, H Maalmi, X Gao, J Chang-Claude, M Hofmeister, H Brenner  Am J Clin Nutr 2021;113(6):1458-67
The costs of inappropriate referral pathways in inpatient care for three major noncommunicable diseases in Mongolia: a national registry-based analysis A Tuvdendorj, O Dechinkhorloo, B Dorjsuren, E Buskens, T Feenstra BMC Health Serv Res 2021;21(1):1280 
The effect of occupational exposure to ergonomic risk factors on osteoarthritis of hip or knee and selected other musculoskeletal diseases: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. CTJ Hulshof, F Pega, S Neupane, C Colosion, JG Daams, KI Proper, et al. Environ Int 2021; 150:106349
The essential role of food composition databases for public health nutrition - Experiences from the Netherlands. MC Ocke, S Westenbrink, CTM van Rossum, WP van der Vossen-Wijmenga, J Verkaik-Kloosterman J Food Compos Anal 2021; 101:103967
The global blue water use for the Dutch diet and associated environmental impact on water scarcity. A Hollander, RE Vellinga, E de Valk, I Toxopeus, M van de Kamp, EHM Temme World J Food Sci Technol 2021; 5(1):10-8
The increasing significance of disease severity in a burden of disease framework. GMA Wyper, R Assuncao, E Fletcher, M Gourley, I Grant, JA Haagsma, H Hilderink, et al. Scand J Public Health 2021; 14034948211024478 advance online publication (ahead of print)
The mediating role of lifestyle in the relationship between shift work, obesity and diabetes. G Hulsegge, KI Proper, B Loef, H Paagman, JR Anema, W van Mechelen Int Arch Occup Environ Health 2021; 94:1287-95
The mediating role of unhealthy behavior in the relationship between shift work and perceived health. KI Proper, E Jaarsma, SJW Robroek, JLD Schram, H Boshuizen, HSJ Picavet, WMM Verschuren, SH van Oostrom BMC Public Health 2021; 21(1):1300
The mediating role of unhealthy behaviors and body mass index in the relationship between high job strain and self-rated poor health among lower educated workers SH van Oostrom, A Nachat, B Loef, KI Proper Int Arch Occup Environ Health 2021; 94:95-105
The national FIT-based colorectal cancer screening program in the Netherlands during the COVID-19 pandemic. TL Kortlever, L de Jonge, PHA Wisse, I Seriese, P Otto-Terlouw, ME van Leerdam, MCW Spaander, E Dekker, I Lansdorp-Vogelaar Prev Med 2021; 151:106643 
The occurrence of non-ATC-INN molecules in suspected illegal or illegally traded health products in Europe: A retro- and prospective study. E Deconinck, C Vanhee, PHJ Keizers, P Guinot, A Mihailova, PV Syversen, G Li-Ship, SA Young, et al. Drug Test Anal 2021; 13(4):833-40
The prevalence of occupational exposure to ergonomic risk factors: A systematic review and meta-analysis from the WHO/ILO Joint estimates of the work-related burden of disease and injury. CTJ Hulshof, F Pega, S Neupane, HF van der Molen, C Colosion, JG Daams, A Descatha, P Kc, KI Proper, et al. Environ Int 2021; 146:106157
The SCCS Notes of Guidance for the Testing of Cosmetic Ingredients and their Safety Evaluation 11th revision, 30-31 March 2021, SCCS/1628/21. U Bernaue, rL Bodin, O Chaudhry, P Coenraads, M Dusinska , J Ezendam, S Wijnhoven, et al. Regul Toxicol Pharmacol 2021; 12:105052
The SCCS Scientific Advice on the Safety of Nanomaterials in Cosmetics. U Bernauer, L Bodin, Q Chaudhry, PJ Coenraads, M Dusinska, E Gaffet, E Panteri, V Rogier, sC Rousselle, M Stepnik, T Vanhaecke, S Wijnhoven, N von Goetz, W de Jong Regul Toxicol Pharmacol 2021; 126: 105046 
The sex difference in gait speed among older adults: how do sociodemographic, lifestyle, social and health determinants contribute? LD Sialino, LA Schaap, SH van Oostrom, HSJ Picavet, JWR Twist, WMM Verschuren, M Visser, HAH Wijnhoven BMC Geriatr 2021; 21(1):340
The uptake and use of telemonitoring in chronic care between 2014 and 2019: Nationwide survey among patients and health care professionals in the Netherlands. MWJ Huygens, HR Voogdt-Pruis, M Wouters, MM Meurs, B van Lettow, C Kleijweg, RD Friele J Med Internet Res 2021; 23(5):e24908
To what extent do citizens support the disinvestment of healthcare interventions? An exploration of the support for four viewpoints on active disinvestment in the Netherlands AH Rotteveel, MS Lambooij RIVM, J van Exel, GA de Wit Soc Sci Med 2021; 293:114662
Topical or oral antibiotics for children with acute otitis media presenting with ear discharge: study protocol of a randomised controlled non-inferiority trial. S Hullegie, RP Venekamp, TMA van Dongen, S Mulder, W van Schaik, GA de Wit BMJ Open 2021;11(12):e052128
Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile. D Ibi, LL Blauw, R Noordam, MET Dollé, JW Jukema, FR Rosendaal, C Christodoulides, MJ Neville, et al. Atherosclerosis 2021; 328:144-52
Ultra-processed food consumption patterns among older adults in the Netherlands and the role of the food environment.  MGM Pinho, J Lakerveld, MC Harbers, I Sluijs, R Vermeulen, A Huss, JMA Boer, WMM Verschuren, J Brug, et al. Eur J Nutr 2021; 60(5):2567-80
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. MB Birkisdottir, D Jaarsma, RMC Brandt, S Barnhoorn, N van Vliet, S Imholz, CT van Oostrom, B Nagarajah, H van Steeg, JLA Pennings, MET Dollé, et al. Aging Cell 2021; e13302 
Uptake of fetal aneuploidy screening after the introduction of the non-invasive prenatal test: a national population-based register study. KRM van der Meij, M de Groot-van Mooren, EWS Carco, MJ Pieters, W Rodenburg, et al. Acta Obstet Gynecol Scan 2021; 100(7):1265-72
Use of food consumption data of food balance sheets and national food consumption surveys in deterministic long-term dietary exposure assessments of pesticides. T van der Velde-Koerts, A Rietveld, PE Boon Food Chem Toxicol 2021; 151:112104
Usefulness and applicability of integrated strategy approaches in toxicology. C Eskes, S Casati, N Kleinstreuer, J Ezendam Appl Vitro Toxicol 2021; 7(3):89-90
Utility of a next generation framework for assessment of genomic damage: a case study using the pharmaceutical drug candidate etoposide. J Nicolette, M Luijten, JC Sasaki, L Custer, M Embry, R Froetsch, lG Johnson, et al. Environ Mol Mutagen 2021 ; 62(9):512-25 
Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021. B de Gier, S Andeweg, R Joosten, R ter Schegget, N Smorenburg, J van de Kassteele, SJM Hahne, s van den Hof, HE de Melker, MJ Knol, et al. Euro Surveill 2021; 26(31):pii.2100640
Variability of in vivo potency tests of Diphtheria, Tetanus and acellular Pertussis (DTaP) vaccines. CAL Stalpers, IA Retmana, JLA Pennings, RJ Vandebriel, CFM Hendriksen, AM Akkermans, MHN Hoefnagel Vaccine 2021; 39(18):2506-16
What influences the outcome of active disinvestment processes in healthcare? A qualitative interview study on five recent cases of active disinvestment. AH Rotteveel, MS Lambooij, JA van de Rijt, J van Excel, KGM Moons, GA de Wit BMC Health Services Research 2021; 21: 298
Why does healthcare utilisation differ between socioeconomic groups in OECD countries with universal healthcare coverage? A protocol for a systematic review I Meulman, E Uiters, J Polder, N Stadhouders BMJ Open 2021;11(11):e054806
Working at Green Care Farms and Other Innovative Small-Scale Long-Term Dementia Care Facilities Requires Different Competencies of Care Staff B de Boer, Y Buist, SR de Bruin, R Backhaus, H Verbeek Int J Environ Res Public Health 2021; 18(20):10747