24 search results
You searched for these word(s): risk assessmentLaunch of the European project RISK-HUNT3R
https://www.rivm.nl/en/news/launch-of-european-project-risk-hunt3r… The new Horizon 2020 project RISK-HUNT3 R : RISK assessment of chemicals integrating HU man centric N … scientists from key industry sectors. The vision of the RISK-HUNT 3R consortium is to establish a reliable and cost-effective chemical risk assessment strategy based entirely on non-animal …
Publication date: 06-03-2021RISK-HUNT3R
https://www.rivm.nl/en/international-projects/risk-hunt3r… The five-year European project RISK-HUNT3 R will develop a novel and modular framework for animal-free Next Generation Risk Assessment (NGRA). The principles of the 3Rs are … The aim of the RISK-HUNT3 R project is to better protect citizens against … constituting the research cluster ASPIS (animal-free safety assessment of chemicals: project cluster for implementation …
Publication date: 05-31-2021MEBI: risk of serious health complaints from Rebound HRD® inguinal hernia mesh
https://www.rivm.nl/en/news/mebi-risk-of-serious-health-complaints-from-rebound-hrdr-inguinal-hernia-mesh… body for a long time, MEBI estimates there is a significant risk of other Rebound HRD® implants breaking in the longer … implants) to MEBI via the following website: rivm.nl/mebi . Risk of metal ring breaking An inguinal hernia mesh normally … for such a long time, MEBI estimates there is a significant risk of the metal wire breaking during the lifespan of the …
Publication date: 06-25-2024Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-pharmaceutical-products… (NAMs) can reduce animal testing for the safety assessment of pharmaceutical products. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products …
Publication date: 03-25-2024Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-chemical-substances… (NAMs) can reduce animal testing for the safety assessment of chemical substances. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances …
Publication date: 11-03-2022Shortcomings in the technical documentation of mesh implants intended to treat pelvic organ prolapse used in the Netherlands
https://www.rivm.nl/en/news/shortcomings-in-technical-documentation-of-mesh-implants-intended-to-treat-pelvic-organ… After a detailed assessment of the technical documentation of nine different … are used to treat patients with pelvic organ prolapse. The assessment was commissioned by the Dutch Health and Youth … the technical documentation. This took place after the RIVM assessment had been completed. Some of the manufacturers …
Publication date: 03-21-2022MACRAME
https://www.rivm.nl/en/international-projects/macrame… to assess and predict the Health and Environmental Risks of Advanced Materials. Within MACRAMÉ, five Advanced … and one on nanomedicine. Furthermore, the hazard and risk assessment after inhalation of these samples shall be … to assess and predict the Health and Environmental Risks of Advanced Materials …
Publication date: 02-23-2023Mesh implants intended to treat pelvic organ prolapse
https://www.rivm.nl/en/news/mesh-implants-intended-to-treat-pelvic-organ-prolapse… examining mesh implants in the laboratory. Technical file assessment Serious complications can occur upon transvaginal … prolapse. Therefore RIVM prioritized the technical file assessment of two transvaginal mesh implants that were still … the product, it means there are uncertainties about the risks. The manufacturers have been given the opportunity to …
Publication date: 02-18-2020Gastric balloons
https://www.rivm.nl/en/medical-devices/gastric-balloons… causes the patient to eat less and lose weight. There are risks associated with the use of gastric balloons. RIVM has studied whether scientific research identified risks that are not currently stated on the instructions for … There are risks associated with the use of gastric balloons. The …
Publication date: 09-19-2024Landscape New Approach Methodologies
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams… be observed in the field of NAM implementation for safety assessment. … Landscape NAMs for the safety assessment of chemical substances … Landscape NAMs for the safety assessment of pharmaceutical products …
Publication date: 11-01-2022News about alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/news… in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop In … in a workshop on building trust in AI for chemical risk assessment, organised by the European Centre for … importance of variations in in vitro dosimetry to support risk assessment of inhaled toxicants Health effects of …
Publication date: 04-21-2023Projects on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/projects… RIVM In vitro liquid-interface | respiratory toxicity | risk assessment 2026-2029 GIANT Strategic Programme RIVM In vitro … 2025-2035 CHIASMA Horizon Europe SSbD | enivronmental risk assessment | chemicals3Rs | alternatives animal testing … RIVM In vitro testing of inhaled substances environmental risk factors | In vitro assays | infectious diseases …
Publication date: 01-25-2023Publications on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/publications… related to alternatives to animal testing and safety assessment of chemicals and pharmaceuticals. … in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop Gant, … Title Authors Journal Towards NAM-based risk assessment for developmental neurotoxic effects, …
Publication date: 11-01-2022Injection needles
https://www.rivm.nl/en/medical-devices/injection-needles… residues. RIVM investigated whether patients’ health was at risk through the use of these needles. …
Publication date: 07-12-2017Computational modelling of neural tube defects
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/computational-modelling-neural-tube-defects… The classical way of safety assessment relies heavily on the use of laboratory animals. … compounds. RIVM investigates the improvement of hazard assessment of developmental toxicants using computational … Toxicity testing should be improved to achieve a better risk assessment in humans. This can be done by combining …
Publication date: 04-03-2023Non-genotoxic carcinogens
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/non-genotoxic-carcinogens… a novel animal-free approach to improve carcinogenic hazard assessment while using fewer animals. … will lead to a better, mechanism-based prediction of the risk of non-genotoxic carcinogenicity due to chemical … A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals Luijten, M., …
Publication date: 03-23-2023Anne Kienhuis appointed Professor of Toxicology in Transition at Utrecht University
https://www.rivm.nl/en/news/anne-kienhuis-appointed-professor-of-toxicology-in-transition-at-utrecht-university… collaboration between RIVM and IRAS ( Institute for Risk Assessment Sciences, University Utrecht) accelerating …
Publication date: 05-27-2025Summary International Expert Meeting on breast implant-associated lymphoma
https://www.rivm.nl/en/news/summary-international-expert-meeting-on-breast-implant-associated-lymphoma… 2018, Dutch research was published that found an increased risk for ALCL in women with breast implants. ALCL is short …
Publication date: 01-31-2019Mesh implants intended to treat pelvic organ prolapse
https://www.rivm.nl/en/medical-devices/mesh-implants-intended-to-treat-pelvic-organ-prolapse… were included in a report published by the IGJ (in Dutch). Assessment of technical documentation The IGJ commissioned … implants. Therefore, as a first step, RIVM completed its assessment of the technical documentation for the two … decided to share the results – provisional pending the full assessment of all selected mesh implants – directly with the …
Publication date: 02-18-2020Fields of expertise on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise… in various methods and approaches to innovate the safety assessment of chemicals and products for humans. Human … In this context, RIVM invests in human-relevant safety assessment of chemicals, thereby investing in the 3Rs and …
Publication date: 11-01-2022