11 search results
You searched for these word(s): poteEffects of endocrine disrupting chemicals
https://www.rivm.nl/en/endocrine-disrupting-chemicals/effects-of-endocrine-disrupting-chemicals… and on how much of the substance you were exposed to. The potential health effects can also depend on the stage of … can affect the hormonal system of humans or other animals, potentially leading to harmful health effects. To classify … adverse outcome. Many studies are currently examining the potential health effects of endocrine disrupting chemicals. …
Publication date: 04-01-2026VAC2VAC
https://www.rivm.nl/en/international-projects/vac2vac… activation assay as a measure of adjuvant function, potentially of use in case of production changes or … on C. tetani neurotoxin expression by RNA sequencing, potentially of use in the manufacturing process of tetanus vaccine. 3. Variability of in vivo potency tests of Diphtheria, Tetanus and acellular Pertussis …
Publication date: 02-19-2020News about alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/news… pregnancy outcomes with pharmaceuticals Assessment of potential developmental and reproductive toxicity is … value of using non-human primates (NHP) to assess potential pharmaceutical effects on male and female … can contribute to earlier and increased detection of potential EDCs. Scientists from RIVM and other institutes …
Publication date: 04-21-2023The role of RIVM
https://www.rivm.nl/en/endocrine-disrupting-chemicals/role-of-rivm… on how to identify endocrine disrupting chemicals and the potential risks of exposure to them. Sharing information … RIVM is active in the international working group on potential hazard issues as part of the UN Globally … increasingly includes the assessment of substances with potential ED properties. RIVM is also commissioned by …
Publication date: 04-01-2026Projects and collaborations
https://www.rivm.nl/en/endocrine-disrupting-chemicals/projects-and-collaborations… various methods, the project aims to understand the potential risks of chemicals that could affect thyroid … ethics. RIVM is involved in developing a human induced pluripotent stem cell-based brain model to study effects on the … new computer models (in silico) that can help identify potential endocrine disrupting chemicals. These models will …
Publication date: 04-01-2026Non-genotoxic carcinogens
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/non-genotoxic-carcinogens… approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals Heusinkveld, H., Braakhuis, H., …
Publication date: 03-23-2023MACRAME
https://www.rivm.nl/en/international-projects/macrame… handling and processing along the product life-cycle Assess potential impacts on (human) health and the environment in …
Publication date: 02-23-2023In vitro testing of inhaled substances
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/inhalation-toxicity… into contact with the pulmonary system through inhalation, potentially causing local effects in the lungs or systemic …
Publication date: 11-01-2022Zebrafish
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/zebrafish… and in silico techniques with zebrafish embryos shows great potential to reduce the need for toxicity testing in …
Publication date: 04-01-2023Reports and publications
https://www.rivm.nl/en/endocrine-disrupting-chemicals/reports-and-publications… reproductive toxicity, and endocrine disruption potential of alternative substances SP den Braver-Sewradj, R …
Publication date: 04-01-2026Publications on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/publications… al. Environment Int 2023; 178:108082 Variability of in vivo potency assays of whole-cell pertussis, inactivated polio, … E. Environmental Health Perspectives 2022; 130(4):047003 Potential of concentration-response data to broaden … and Molecular Mutagenesis 2022; 63(3):118-34 Pluripotent stem cell assays: Modalities and applications for …
Publication date: 11-01-2022