20 search results
You searched for these word(s): risk assessmentLaunch of the European project RISK-HUNT3R
https://www.rivm.nl/en/news/launch-of-european-project-risk-hunt3r… The new Horizon 2020 project RISK-HUNT3 R : RISK assessment of chemicals integrating HU man centric N … scientists from key industry sectors. The vision of the RISK-HUNT 3R consortium is to establish a reliable and cost-effective chemical risk assessment strategy based entirely on non-animal …
Publication date: 06-03-2021RISK-HUNT3R
https://www.rivm.nl/en/international-projects/risk-hunt3r… The five-year European project RISK-HUNT3 R will develop a novel and modular framework for animal-free Next Generation Risk Assessment (NGRA). The principles of the 3Rs are … The aim of the RISK-HUNT3 R project is to better protect citizens against … constituting the research cluster ASPIS (animal-free safety assessment of chemicals: project cluster for implementation …
Publication date: 05-31-2021Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-pharmaceutical-products… (NAMs) can reduce animal testing for the safety assessment of pharmaceutical products. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products …
Publication date: 03-25-2024Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-chemical-substances… (NAMs) can reduce animal testing for the safety assessment of chemical substances. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances …
Publication date: 11-03-2022MACRAME
https://www.rivm.nl/en/international-projects/macrame… to assess and predict the Health and Environmental Risks of Advanced Materials. Within MACRAMÉ, five Advanced … and one on nanomedicine. Furthermore, the hazard and risk assessment after inhalation of these samples shall be … to assess and predict the Health and Environmental Risks of Advanced Materials …
Publication date: 02-23-2023Landscape New Approach Methodologies
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams… be observed in the field of NAM implementation for safety assessment. … Landscape NAMs for the safety assessment of chemical substances … Landscape NAMs for the safety assessment of pharmaceutical products …
Publication date: 11-01-2022News about alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/news… June 2026: NAMs for closing knowledge gaps in assessment of respiratory uptake – a PARC project … (MNPs) are present in our environment, but their potential risks to human health are limited. RIVM researchers have … safety profiling algorithm (ASPA) for next generation risk assessment (NGRA) To operationalize next-generation …
Publication date: 04-21-2023Projects on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/projects… substances AOP | inhalation | computational modelling | risk assessment 2026-2029 ThyroTransVal ValNAM – ZonMw/BMFTR … 2025-2029 CHIASMA Horizon Europe SSbD | enivronmental risk assessment | chemicals3Rs | alternatives animal testing … RIVM In vitro testing of inhaled substances environmental risk factors | In vitro assays | infectious diseases …
Publication date: 01-25-2023Publications on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/publications… related to alternatives to animal testing and safety assessment of chemicals and pharmaceuticals. … in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop Gant, … Title Authors Journal Towards NAM-based risk assessment for developmental neurotoxic effects, …
Publication date: 11-01-2022Computational modelling of neural tube defects
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/computational-modelling-neural-tube-defects… The classical way of safety assessment relies heavily on the use of laboratory animals. … compounds. RIVM investigates the improvement of hazard assessment of developmental toxicants using computational … Toxicity testing should be improved to achieve a better risk assessment in humans. This can be done by combining …
Publication date: 04-03-2023Non-genotoxic carcinogens
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/non-genotoxic-carcinogens… a novel animal-free approach to improve carcinogenic hazard assessment while using fewer animals. … will lead to a better, mechanism-based prediction of the risk of non-genotoxic carcinogenicity due to chemical … A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals Luijten, M., …
Publication date: 03-23-2023Anne Kienhuis appointed Professor of Toxicology in Transition at Utrecht University
https://www.rivm.nl/en/news/anne-kienhuis-appointed-professor-of-toxicology-in-transition-at-utrecht-university… collaboration between RIVM and IRAS ( Institute for Risk Assessment Sciences, University Utrecht) accelerating …
Publication date: 05-27-2025New research methods
https://www.rivm.nl/en/medicinal-products/new-research-methods… Inclusion into guidelines In order to be used in the safety assessment of medicinal products, new research methods must … Landscape for New Approach Methodologies (NAMs) for safety assessment of pharmaceutical products. Understanding these … projects to develop new research methods for the safety assessment of chemicals and medicines, such as within Ombion …
Publication date: 06-24-2026Fields of expertise on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise… in various methods and approaches to innovate the safety assessment of chemicals and products for humans. Human … In this context, RIVM invests in human-relevant safety assessment of chemicals, thereby investing in the 3Rs and …
Publication date: 11-01-2022Quality and control
https://www.rivm.nl/en/medicinal-products/quality-control… process. Prior to the market authorization, the quality assessment is based on the manufacturer's dossier. Given the …
Publication date: 05-18-2026MERLON
https://www.rivm.nl/en/international-projects/merlon… world-leading experts in endocrinology, chemical safety assessment, developmental and molecular biology, …
Publication date: 07-31-2025Zebrafish
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/zebrafish… on skeletal development and liver disease, and explore assessment strategies for chemical mixtures. The combination …
Publication date: 04-01-2023Policy advice
https://www.rivm.nl/en/medicinal-products/policy-advice… looks into access to medicines and to their effects and risks for public health. Other topics we advise about are: … context of thrombosis with thrombocytopenia syndrome (TTS): risk awareness and adherence (TTS-RiskAware). Impact of EU label changes and pregnancy …
Publication date: 05-18-2026Illegal medicines
https://www.rivm.nl/en/medicinal-products/illegal-medicines… shared: Committee of Experts on Minimising Public Health Risks Posed by Falsification of Medical Products and Similar … on substandard and falsified medical products Health risks There are several risks associated with the use of falsified medicines. Some …
Publication date: 05-18-2026Control of medicines
https://www.rivm.nl/en/medicinal-products/control-of-medicines… signals or doubts about the product’s quality Associated risks of medicinal products selected through the …
Publication date: 06-24-2026