30 search results
You searched for these word(s): risk assessmentLaunch of the European project RISK-HUNT3R
https://www.rivm.nl/en/news/launch-of-european-project-risk-hunt3r… The new Horizon 2020 project RISK-HUNT3 R : RISK assessment of chemicals integrating HU man centric N … scientists from key industry sectors. The vision of the RISK-HUNT 3R consortium is to establish a reliable and cost-effective chemical risk assessment strategy based entirely on non-animal …
Publication date: 06-03-2021RISK-HUNT3R
https://www.rivm.nl/en/international-projects/risk-hunt3r… The five-year European project RISK-HUNT3 R will develop a novel and modular framework for animal-free Next Generation Risk Assessment (NGRA). The principles of the 3Rs are … The aim of the RISK-HUNT3 R project is to better protect citizens against … constituting the research cluster ASPIS (animal-free safety assessment of chemicals: project cluster for implementation …
Publication date: 05-31-2021Direct link between Tata Steel emissions, nuisance and risk of disease
https://www.rivm.nl/en/news/direct-link-between-tata-steel-emissions-nuisance-and-risk-of-disease… putting people who live in the IJmond region at an elevated risk of disease. The greatest benefits to public health in … from various disciplines, RIVM was able to assess the risk of becoming ill as a result of emissions from the Tata … who experience noise, odour and dust nuisance. Largest risk of adverse health effects in Wijk aan Zee This resulted …
Publication date: 09-22-2023Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-pharmaceutical-products… (NAMs) can reduce animal testing for the safety assessment of pharmaceutical products. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of pharmaceutical products …
Publication date: 03-25-2024Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams/safety-assessment-chemical-substances… (NAMs) can reduce animal testing for the safety assessment of chemical substances. However, implementing … Landscape New Approach Methodologies (NAMs) for the safety assessment of chemical substances …
Publication date: 11-03-2022Children's exposure to chemical substances
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/children-s-exposure… Knowledge on the exposure part of the risk assessment is equally important as knowledge on the … endpoints, but this knowledge is scarce. In exposure assessment, attention for a sensitive subpopulation such as … awareness for the inclusion of children’s exposure in risk assessments, specifically in a product safety …
Publication date: 02-01-2012Proclaimer
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/consexpo-nano/model-documentation-and-user-manual/proclaimer… It is recommended that experts (nanotoxicology, exposure assessment and risk assessment) are responsible for the evaluation and … of the results of the model is required as a basis for risk assessment. RIVM is not responsible for the …
Publication date: 04-23-2020Modelling exposure to nanomaterials in spray products
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/Consexpo%20Nano/model-documentation-and-user-manual/modelling-exposure-to-nanomaterials-in-spray-products-0… is expressed in different dose metrics for quantitative risk assessment. For comparison of the exposure evaluation in … In the risk assessment for regular (i.e. non-nano material) substances, … mass does not seem to be an appropriate metric to base the risk characterisation on. Different alternative dose …
Publication date: 04-23-2020User manual ConsExpo Nano Tool
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/consexpo-nano/model-documentation-and-user-manual/user-manual… An assessment is defined by specifying input for all model … as an estimate of exposure. Alternatively, probabilistic assessments can be conducted. This is done by providing a … Local file management The user may store and retrieve assessments via the ‘import’ and ‘export’ buttons. …
Publication date: 04-23-2020MACRAME
https://www.rivm.nl/en/international-projects/macrame… to assess and predict the Health and Environmental Risks of Advanced Materials. Within MACRAMÉ, five Advanced … and one on nanomedicine. Furthermore, the hazard and risk assessment after inhalation of these samples shall be … to assess and predict the Health and Environmental Risks of Advanced Materials …
Publication date: 02-23-2023Working with the DustEx web application
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/dustex/working-with-the-dustex-web-application2… parameters is scarce. To assist in performing exposure assessments with the DustEx model a compilation of available … do not depend on the substance and product for which the assessment is conducted) defaults are suggested in the web … fields. In this way an uncertainty analysis of the exposure assessment can be performed. A brief discussion on how …
Publication date: 05-14-2020The DustEx modelling tool
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/dustex… all pathways and will therefore enable a more complete assessment of exposure, reducing the probability of overlooking the most crucial pathways in the exposure assessment. In developing the DustEx model, a number of … put limits on the applicability of the model in exposure assessments. Model framework The DustEx model is a kinetic …
Publication date: 04-20-2020References
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/DustEx/References… Veen MP. 2002. Children’s toys fact sheet. To assess the risks for the consumer. RIVM report 612810012/2002. Delmaar … from solid matrices. A method for consumer exposure assessment. RIVM Report 320104011. Ionas AC, Ulevicus J, …
Publication date: 05-14-2020Mercury in Groningen’s natural gas not harmful to health
https://www.rivm.nl/en/news/mercury-in-groningens-natural-gas-not-harmful-to-health… RIVM to investigate whether this exposure could pose health risks. The results show that exposure to mercury through … NAM’s calculations and assess whether there were any health risks associated with peak exposure to mercury. RIVM …
Publication date: 06-12-2023Landscape New Approach Methodologies
https://www.rivm.nl/en/alternatives-to-animal-testing/landscape-nams… be observed in the field of NAM implementation for safety assessment. … Landscape NAMs for the safety assessment of chemical substances … Landscape NAMs for the safety assessment of pharmaceutical products …
Publication date: 11-01-2022News about alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/news… in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop In … in a workshop on building trust in AI for chemical risk assessment, organised by the European Centre for … importance of variations in in vitro dosimetry to support risk assessment of inhaled toxicants Health effects of …
Publication date: 04-21-2023Projects on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/projects… RIVM In vitro liquid-interface | respiratory toxicity | risk assessment 2026-2029 GIANT Strategic Programme RIVM In vitro … 2025-2035 CHIASMA Horizon Europe SSbD | enivronmental risk assessment | chemicals3Rs | alternatives animal testing … RIVM In vitro testing of inhaled substances environmental risk factors | In vitro assays | infectious diseases …
Publication date: 01-25-2023Publications on alternatives to animal testing
https://www.rivm.nl/en/alternatives-to-animal-testing/publications… related to alternatives to animal testing and safety assessment of chemicals and pharmaceuticals. … in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop Gant, … Title Authors Journal Towards NAM-based risk assessment for developmental neurotoxic effects, …
Publication date: 11-01-2022Computational modelling of neural tube defects
https://www.rivm.nl/en/alternatives-to-animal-testing/fields-of-expertise/computational-modelling-neural-tube-defects… The classical way of safety assessment relies heavily on the use of laboratory animals. … compounds. RIVM investigates the improvement of hazard assessment of developmental toxicants using computational … Toxicity testing should be improved to achieve a better risk assessment in humans. This can be done by combining …
Publication date: 04-03-2023ConsExpo nano
https://www.rivm.nl/en/consumer-exposure-to-chemical-substances/exposure-models/consexpo-nano… human inhalation exposure giving a first indication of the risk after that specific exposure to nanomaterials. Update … have been added. Depending on the hazard information in the risk assessment, doses are more appropriately expressed in …
Publication date: 04-20-2020