58 search results
You searched for these word(s): risk assessmentEfficient risk assessment for nanomaterials in aquatic systems: IATAs to support grouping and read-across
https://www.rivm.nl/en/weblog/efficient-risk-assessment-for-nanomaterials-in-aquatic-systems-iatas-to-support-grouping-and… Integrated approaches to testing and assessment (IATAs) can optimise testing strategies and minimise the use of test animals in chemical risk assessment. Recently, aquatic IATAs have been developed that … Efficient risk assessment for nanomaterials in aquatic systems: IATAs to …
Publication date: 04-30-2024AI for chemical risk assessment: promises and concerns
https://www.rivm.nl/en/weblog/ai-for-chemical-risk-assessment-promises-and-concerns… increasing and has the potential to revolutionize chemical risk assessment. For predicting the toxicity of … asked about their views on the use of AI for chemical risk assessment. Revolutionizing risk assessment with AI: predicting toxicity without animal … AI for chemical risk assessment: promises and concerns …
Publication date: 03-26-2024New approach methodologies for risk assessment and safe-and-sustainable by design of nanomaterials.
https://www.rivm.nl/en/weblog/new-approach-methodologies-for-risk-assessment-and-safe-and-sustainable-by-design-of… (NAMs). One focussed on the purpose of regulatory risk assessment and the other on in silico methods for the … nanomaterials, most still require validation for regulatory risk assessment purposes. Investment in validating test … NAMs are innovative technologies used in hazard and risk assessment. They aim to reduce or replace traditional …
Publication date: 10-03-2024New study reveals impact of nanoparticles on placental function and vascular growth - implications for risk assessment
https://www.rivm.nl/en/weblog/new-study-reveals-impact-of-nanoparticles-on-placental-function-and-vascular-growth… to use this model as a standard test for regulatory risk assessment because of ethical concerns surrounding the … placental function and vascular growth - implications for risk assessment …
Publication date: 12-19-2024Understanding the degradation of 2D materials: Implications for human health and environmental safety assessment
https://www.rivm.nl/en/weblog/understanding-degradation-of-2d-materials-implications-for-human-health-and-environmental… of understanding these degradation processes for the safety assessment of these materials. However, appropriate … of these materials is essential for evaluating risks to both human health and the environment. Types of … Implications for human health and environmental safety assessment …
Publication date: 04-01-2025Human biomonitoring for investigating exposure to nanomaterials
https://www.rivm.nl/en/weblog/human-biomonitoring-for-investigating-exposure-to-nanomaterials… Human biomonitoring can help improve (occupational) risk assessment, provided that a clear relationship exists …
Publication date: 07-17-2024Artificial Intelligence/Machine Learning and advanced materials
https://www.rivm.nl/en/weblog/artificial-intelligencemachine-learning-and-advanced-materials… which can potentially be used for optimized hazard and risk assessment of advanced materials. In this way, the … of advanced materials, which is crucial for effective risk assessment. Additionally, ML can assist in establishing … will be a focus on using AI and ML for optimized hazard and risk assessment. This is a positive development, as it …
Publication date: 12-19-2024Twenty years of adaptations in European legislation for nanomaterials: we are not there yet
https://www.rivm.nl/en/weblog/twenty-years-of-adaptations-in-european-legislation-for-nanomaterials-we-are-not-there-yet… Danish researchers assessed recommendations for adjustments to legislation for … Advanced materials may pose additional challenges in risk assessment. The legislation amendments for … may not necessarily identify potential hazards and risks for advanced materials. European nanomaterial …
Publication date: 04-30-2024A new Adverse Outcome Pathway to assess if nanomaterials may compromise gut barrier integrity
https://www.rivm.nl/en/weblog/new-adverse-outcome-pathway-to-assess-if-nanomaterials-may-compromise-gut-barrier-integrity… the AOP and associated testing methods are relevant for the risk assessment of NMs. An AOP for a compromised gut barrier … methods has the potential to be highly relevant for the risk assessment of NMs. …
Publication date: 06-12-2025Additional environmental risks of nanopesticides to be regarded
https://www.rivm.nl/en/weblog/additional-environmental-risks-of-nanopesticides-to-be-regarded… properties can also pose additional environmental risks. For example, higher or prolonged exposure of non-target organisms. Current risk assessment frameworks do not sufficiently address these … Additional environmental risks of nanopesticides to be regarded …
Publication date: 07-17-2024Ensuring Safety and Sustainability of Advanced Materials: A Call for Enhanced Focus in the Chemistry Industry Action Plan
https://www.rivm.nl/en/weblog/ensuring-safety-and-sustainability-of-advanced-materials-call-for-enhanced-focus-in… for "advanced" materials and the challenges in properly assessing their safety and lifecycle risks are a concern. This highlights the need for reliable data and established test methods and risk assessment methodologies targeted at advanced materials …
Publication date: 11-06-2025OECD proposes tiered approach for testing bioaccumulation of nanomaterials
https://www.rivm.nl/en/weblog/oecd-proposes-tiered-approach-for-testing-bioaccumulation-of-nanomaterials… Bioaccumulation assessment of nanomaterials cannot be done using the … Therefore, the current guidance on bioaccumulation assessment is not suitable for nanomaterials. To address … testing is required for regulatory chemical risk assessment, including for nanomaterials. When chemicals …
Publication date: 04-30-2024Laws and regulations
https://www.rivm.nl/en/nanotechnology/laws-and-regulations… Due to the unique properties of advanced (nano)materials, risk assessment methods sometimes need to be adapted. This also … to the laws and regulations that set requirements for such assessments. RIVM assists the European Commission and Dutch … in the research and innovation that they support. Risk assessment of advanced (nano)materials The risk …
Publication date: 07-19-2012EFSA introduces new guidance for evaluating dissolution of nanomaterials in fat
https://www.rivm.nl/en/weblog/efsa-introduces-new-guidance-for-evaluating-dissolution-of-nanomaterials-in-fat… (K OW ) method nanospecific considerations for safety assessments may potentially be waived. However, EFSA also … limitations make it difficult to apply this method to risk assessments of nanoparticles used in applications other than …
Publication date: 12-19-2024Titanium dioxide in foods
https://www.rivm.nl/en/nanotechnology/application-in-products/titanium-dioxide-in-foods… particles consists of nanoparticles. To enable a proper assessment of the potential health risks of titanium dioxide nanoparticles in food products, it … with others, RIVM is examining the potential health risks of titanium dioxide in foods. … form, and surface characteristics complicate the risk assessment of titanium dioxide. Uncertain risks The …
Publication date: 08-21-2018Following up on lessons learned from graphene flagship
https://www.rivm.nl/en/weblog/following-up-on-lessons-learned-from-graphene-flagship… the EU Graphene Flagship have highlighted the complexity of assessing the safety of graphene and related materials. Such assessment requires detailed knowledge of safety-related … chemicals regulation REACH. This may also allow safety assessment of graphene and related materials. The …
Publication date: 03-26-2024Rethinking regulation: Should nanomaterials be considered biological entities?
https://www.rivm.nl/en/weblog/rethinking-regulation-should-nanomaterials-be-considered-biological-entities… list various well-known challenges regarding the safety assessment of nanomaterials. However, they do not provide … several challenges and difficulties related to safety assessment of nanomaterials. One example given is that the … that should be addressed in their regulatory safety assessment. However, the perspective does not offer a clear …
Publication date: 12-19-2024Out of REACH? Regulatory challenges for multicomponent nanomaterials
https://www.rivm.nl/en/weblog/out-of-reach-regulatory-challenges-for-multicomponent-nanomaterials… uncertainties remain regarding their categorisation and assessment. More precise definitions and guidelines are … their solubility and dissolution, it is unclear whether the assessment should focus on a single or multiple components. …
Publication date: 06-12-2025Commission communication on advanced materials for industrial leadership: measures on safety and sustainability are lacking
https://www.rivm.nl/en/weblog/commission-communication-on-advanced-materials-for-industrial-leadership-measures-on-safety… while acknowledging their human health and environmental risks. The European Commission’s 2024 communication … for implementing timely, anticipatory actions to minimise risks and ensure responsible innovation. Key elements to … the EC in 2022, provides a five-step assessment to identify risks, find safer alternatives, and prevent costly …
Publication date: 04-01-2025Can foliar nanoforms of fertilisers be used beneficially?
https://www.rivm.nl/en/weblog/can-foliar-nanoforms-of-fertilisers-be-used-beneficially… the nanospecific properties of these products when assessing the benefits and risks for crops, the environment, and human health. What are … Product Regulation, there is an increased focus on assessing the human and environmental safety aspects …
Publication date: 10-03-2024