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You searched for these word(s): risk assessmentNew safety data confirms hydroxyapatite in nanoform is safe for oral care products
https://www.rivm.nl/en/weblog/new-safety-data-confirms-hydroxyapatite-in-nanoform-is-safe-for-oral-care-products… and is not significantly taken up by cells. The safety assessment applies only to specific types of HAP … on HAP nano comes after the SCCS’s fourth review. Earlier assessments by the SCCS were inconclusive regarding the … do not meet these criteria will require a separate safety assessment. Reflection by RIVM The case of HAP nano …
Publication date: 09-15-2025Advanced materials in the energy transition and their impact on human and environmental health
https://www.rivm.nl/en/weblog/advanced-materials-in-energy-transition-and-their-impact-on-human-and-environmental-health… transition. These advanced materials may pose potential risks to human health and the environment. To ensure that … itself does not create new health, environmental or social risks, it is necessary to carefully consider the safety and … advancements bring many benefits, they may also pose new risks to human health and the environment. The agency’s …
Publication date: 11-06-2025Enhancing focus on safety and sustainability could benefit the European Union’s ambition to excel in advanced materials
https://www.rivm.nl/en/weblog/enhancing-focus-on-safety-and-sustainability-could-benefit-european-unions-ambition-to-excel… The past few decades of managing the uncertain risks for human and environment associated with … provide their vast experience with governing the uncertain risks of nanotechnology. They use this to emphasise the … industry, SMEs, and the public regarding potential risks and impacts of advanced materials. Key actions based …
Publication date: 10-03-2024Electronic waste as a source of nanoparticles
https://www.rivm.nl/en/weblog/electronic-waste-as-source-of-nanoparticles… However, it is important to consider the possible risks associated with this process to maximise its positive …
Publication date: 04-30-2024What does RIVM do?
https://www.rivm.nl/en/nanotechnology/what-does-rivm-do… advanced (nano)materials. We investigate whether the health risks posed to humans and the environment can be assessed … KIR-nano, the Knowledge and information centre on Risks of nanotechnology, is operational since 2007. It … ”, several times a year. Research projects focused on risk assessment The aim of RIVM’s research and activities is to …
Publication date: 07-19-2012Responsible innovation with nanomaterials and nanotechnology: past, present, future
https://www.rivm.nl/en/weblog/responsible-innovation-with-nanomaterials-and-nanotechnology-past-present-future… into everyday life accelerates, understanding the risks and benefits of these materials becomes crucial, … and clean energy applications. Balancing benefits and risks is key Understanding how nanomaterials move, … to managing both benefits—like cleaner energy systems—and risks, such as nanoparticle pollution. The overarching …
Publication date: 12-18-2025Safety of materials and products already starts at the design phase
https://www.rivm.nl/en/news/safety-of-materials-and-products-already-starts-at-design-phase… technological developments are safe in 2050. When health risks for people and planet are taken into account in the … as other chemicals, they may potentially pose health risks. Safe-by-Design is about ensuring that safety is … key role in this context, not least in rapid and effective assessment of the impact substances can have. This approach …
Publication date: 10-26-2021Implications for humans and the environment
https://www.rivm.nl/en/nanotechnology/implications-for-humans-and-the-environment… At the same time, it is difficult to predict the potential risks. For example, some particles are poorly soluble and … is often still uncertain, but there is evidence of their risk in certain situations. For example, inhalation of these …
Publication date: 07-19-2012Early4AdMa demonstrates value by identifying potential regulatory issues and research needs for nanocarriers
https://www.rivm.nl/en/weblog/early4adma-demonstrates-value-by-identifying-potential-regulatory-issues-and-research-needs… In various chemical domains this needs to be critically assessed in more detail. Further, research activities should …
Publication date: 04-30-2024SAbyNA
https://www.rivm.nl/en/international-projects/sabyna… consists of a step-by-step approach to identify potential risks and to indicate options for managing these risks, both by adapting the design of the product and by … and occupational health and safety data for the different assessments. • A simplified Life Cycle Assessment (LCA) …
Publication date: 02-26-2020EFSA’s re-evaluation of silver as a food additive is inconclusive
https://www.rivm.nl/en/weblog/efsas-re-evaluation-of-silver-as-food-additive-is-inconclusive… its safety due to critical gaps in scientific data. The assessment was intended to address questions surrounding the … data to determine whether the additive posed a health risk. In response, the European Commission invited … necessary information and quality to support a conclusive risk assessment. Insufficient data on particle form and …
Publication date: 09-15-2025European Parliament rejects new nanomaterial definition in Novel Food Regulation
https://www.rivm.nl/en/weblog/european-parliament-rejects-new-nanomaterial-definition-in-novel-food-regulation… clear and objective criteria and alignment with the EFSA risk assessment guidance documents on nanotechnology . The … to a better protection of consumers. According to the EFSA risk assessment guidance on nanotechnology , nano-specific …
Publication date: 07-17-2024An industry guide to implement a Safe and Sustainable by Design innovation process
https://www.rivm.nl/en/weblog/industry-guide-to-implement-safe-and-sustainable-by-design-innovation-process… severe adverse effects such as carcinogenicity. Related to assessments in SSbD, also trade-offs between different … goal is to ensure thorough safety implementation through a risk-based assessment. This should take into account the … is committed to advancing knowledge about toxicological risks for humans and the environment, particularly in …
Publication date: 07-17-2024New approach methodologies to study intestinal fate of nanomaterials: current understanding and knowledge gaps
https://www.rivm.nl/en/weblog/new-approach-methodologies-to-study-intestinal-fate-of-nanomaterials-current-understanding… knowledge gaps remain, especially in standardising and assessing how well these models mimic human biology and … human health. The intestinal uptake of NMs is critical for assessing their systemic effects. The intestine serves as a … strengthen the scientific and regulatory foundations for assessing the intestinal fate of ingested NMs. The document …
Publication date: 12-18-2025Food products from outside the EU still can contain titanium dioxide (E 171)
https://www.rivm.nl/en/weblog/food-products-from-outside-eu-still-can-contain-titanium-dioxide-e-171… that there is no solid evidence that E 171 poses a health risk. While they acknowledge uncertainties about its … and potential health outcomes. Uncertainties inherent to risk assessment Apart from the different assumptions mentioned …
Publication date: 03-26-2024Screening Approach to the Safe-and-Sustainable-by-Design Development
https://www.rivm.nl/en/weblog/screening-approach-to-safe-and-sustainable-by-design-development… by the OECD . Tier 1 of Early4AdMa is a simple screening assessment based on the NESSI score (Novelty, Exposure, … scores high, it moves to Tier 2 for a more detailed assessment of the warnings from Tier 1. The value of … be released during mat installation, posing an inhalation risk for workers. There was no expected exposure to …
Publication date: 10-03-2024Genotoxicity of titanium dioxide in cosmetics cannot be excluded
https://www.rivm.nl/en/weblog/genotoxicity-of-titanium-dioxide-in-cosmetics-cannot-be-excluded… of studies should be improved to reduce uncertainty in assessment. Why does SCCS come with this advice on titanium … products revealed several shortcomings in the safety assessment. For nano-grade TiO2, more information is needed … Overall, further investigation is needed to assess the risk to the consumer from long-term repeated exposure to …
Publication date: 10-03-2024Machine learning to identify key factors in titanium dioxide nanoparticle genotoxicity; a work in progress
https://www.rivm.nl/en/weblog/machine-learning-to-identify-key-factors-in-titanium-dioxide-nanoparticle-genotoxicity-work… handling outliers and validating the model warrants further assessment. The findings of this study are therefore not … presents an interesting approach that uses ML for hazard assessment. If developed further, these methods could be valuable for hazard and risk assessment. However, in its current set-up, the …
Publication date: 12-18-2025EU Court upholds annulment of classification of Titanium dioxide in certain powder forms
https://www.rivm.nl/en/weblog/eu-court-upholds-annulment-of-classification-of-tio2-in-certain-powder-forms… had cancelled the classification, stating that the original assessment had not considered all relevant factors. In the … In 2017, the European Chemicals Agency (ECHA) Committee for Risk Assessment (RAC) agreed with the classification as …
Publication date: 11-06-2025New approach uses cell changes to identify hazardous, rigid fibres
https://www.rivm.nl/en/weblog/new-approach-uses-cell-changes-to-identify-hazardous-rigid-fibres… fibres A study suggests a new approach to assessing the risk posed by morphology-induced hazards. This study was performed by the German Federal Institute for Risk Assessment (BfR). It used ‘omics data from different …
Publication date: 04-30-2024