60 search results
You searched for these word(s): risk assessmentScreening Approach to the Safe-and-Sustainable-by-Design Development
https://www.rivm.nl/en/weblog/screening-approach-to-safe-and-sustainable-by-design-development… by the OECD . Tier 1 of Early4AdMa is a simple screening assessment based on the NESSI score (Novelty, Exposure, … scores high, it moves to Tier 2 for a more detailed assessment of the warnings from Tier 1. The value of … be released during mat installation, posing an inhalation risk for workers. There was no expected exposure to …
Publication date: 10-03-2024Genotoxicity of titanium dioxide in cosmetics cannot be excluded
https://www.rivm.nl/en/weblog/genotoxicity-of-titanium-dioxide-in-cosmetics-cannot-be-excluded… of studies should be improved to reduce uncertainty in assessment. Why does SCCS come with this advice on titanium … products revealed several shortcomings in the safety assessment. For nano-grade TiO2, more information is needed … Overall, further investigation is needed to assess the risk to the consumer from long-term repeated exposure to …
Publication date: 10-03-2024Machine learning to identify key factors in titanium dioxide nanoparticle genotoxicity; a work in progress
https://www.rivm.nl/en/weblog/machine-learning-to-identify-key-factors-in-titanium-dioxide-nanoparticle-genotoxicity-work… handling outliers and validating the model warrants further assessment. The findings of this study are therefore not … presents an interesting approach that uses ML for hazard assessment. If developed further, these methods could be valuable for hazard and risk assessment. However, in its current set-up, the …
Publication date: 12-18-2025EU Court upholds annulment of classification of Titanium dioxide in certain powder forms
https://www.rivm.nl/en/weblog/eu-court-upholds-annulment-of-classification-of-tio2-in-certain-powder-forms… had cancelled the classification, stating that the original assessment had not considered all relevant factors. In the … In 2017, the European Chemicals Agency (ECHA) Committee for Risk Assessment (RAC) agreed with the classification as …
Publication date: 11-06-2025New approach uses cell changes to identify hazardous, rigid fibres
https://www.rivm.nl/en/weblog/new-approach-uses-cell-changes-to-identify-hazardous-rigid-fibres… fibres A study suggests a new approach to assessing the risk posed by morphology-induced hazards. This study was performed by the German Federal Institute for Risk Assessment (BfR). It used ‘omics data from different …
Publication date: 04-30-2024Testing of nanomaterials and advanced materials remains a challenge
https://www.rivm.nl/en/weblog/testing-of-nanomaterials-and-advanced-materials-remains-challenge… testing of chemicals To enable internationally harmonised risk assessment of chemicals, research groups and regulatory …
Publication date: 10-03-2024Impact of Dispersion Methods on Nanoparticle Toxicity: A Call for Better Guidance
https://www.rivm.nl/en/weblog/impact-of-dispersion-methods-on-nanoparticle-toxicity-call-for-better-guidance… interpreting the results of these studies in the context of risk assessment of particles and for comparison with real-life …
Publication date: 11-06-2025Transforming waste into valuable resources: innovations in sustainable nanoparticle synthesis
https://www.rivm.nl/en/weblog/transforming-waste-into-valuable-resources-innovations-in-sustainable-nanoparticle-synthesis… Consequently, the existing issues surrounding their risk assessment remain, including knowledge gaps on long-term …
Publication date: 12-18-2025Application in products
https://www.rivm.nl/en/nanotechnology/application-in-products… advanced (nano)materials. These nanoparticles can pose risks to human health. The European Food Safety Authority … in a product. Scientists are still debating the potential risks associated with inhaling titanium dioxide …
Publication date: 07-19-2012SCCS raises concern over the safety of fullerenes in cosmetic products
https://www.rivm.nl/en/weblog/sccs-raises-concern-over-safety-of-fullerenes-in-cosmetic-products… the Cosmetic Regulation ((EC) No. 1223/2009 ). Safety assessment by SCCS The European Commission (EC) is … nanomaterials that are of concern and must undergo a safety assessment. If the data is insufficient, the EC must ban …
Publication date: 03-26-2024Prediction of In Vivo Behaviour of Nanoparticles Using PBPK Models: Key Findings and Recommendations
https://www.rivm.nl/en/weblog/prediction-of-in-vivo-behaviour-of-nanoparticles-using-pbpk-models-key-findings-and… based kinetic (PBK) models for regulatory safety assessments of conventional chemicals. However, significant …
Publication date: 06-02-2026EU highlights strategic importance of advanced materials for medical devices
https://www.rivm.nl/en/weblog/eu-highlights-strategic-importance-of-advanced-materials-for-medical-devices… sectors, including the medical devices sector. The impact assessment for the Advanced Materials Act will incorporate …
Publication date: 06-02-2026Collaboration and funding are critical in the development of test methods
https://www.rivm.nl/en/weblog/collaboration-and-funding-are-critical-in-development-of-test-methods… member countries to accept each other’s data for safety assessments of chemicals and materials, as long as the …
Publication date: 03-26-2024Working safely with advanced (nano)materials
https://www.rivm.nl/en/nanotechnology/working-safely-with-advanced-nanomaterials… particles poses the most significant and common health risk in the workplace. Additionally, exposure can occur … actions. Given the uncertainties surrounding the health risks associated with advanced (nano)materials, the … en preventie (Nanomaterials in Health Care: occupational risks and prevention) Nanomaterialen in onderhoudswerk: …
Publication date: 07-19-2012Estimated intake of titanium dioxide via medicines
https://www.rivm.nl/en/weblog/estimated-intake-of-titanium-dioxide-via-medicines… safety and efficacy of these formulations requires reassessment by regulatory authorities. This process might … increased. For food additives, uncertainty about a possible risk can lead to banning their use. In contrast, for medicines, a benefit-risk evaluation must be performed, which means that certain …
Publication date: 12-19-2024Potential of nanomaterials in food packaging to improve food safety and sustainability
https://www.rivm.nl/en/weblog/potential-of-nanomaterials-in-food-packaging-to-improve-food-safety-and-sustainability… Using nanomaterials in food packaging can help reduce such risks. However, it is essential to be aware that … migrate from packaging into food, so the potential risks to human health from the nanomaterials themselves must …
Publication date: 09-15-2025NanoReg2
https://www.rivm.nl/en/international-projects/nanoregii… concept aims to reduce potential health and environmental risks early in the innovation process. Such a concept aims … process of a product/material, to eliminate or minimise the risk of adverse effects during its life cycle including …
Publication date: 01-04-2016Advancements in metal-organic frameworks: an approach for safe, sustainable and effective industrial application
https://www.rivm.nl/en/weblog/advancements-in-metal-organic-frameworks-approach-for-safe-sustainable-and-effective… that could hinder the material’s proper functioning or pose risks to human health and the environment. What are MOFs …
Publication date: 09-15-2025Early identification of safety, sustainability and regulatory issues of titanium carbide MXenes
https://www.rivm.nl/en/weblog/early-identification-of-safety-sustainability-and-regulatory-issues-of-titanium-carbide… By identifying potential issues early on, the tool supports risk governance and helps formulate appropriate follow-up …
Publication date: 12-18-2025UK workshops foster collaboration for safe and sustainable innovation in advanced materials
https://www.rivm.nl/en/weblog/uk-workshops-foster-collaboration-for-safe-and-sustainable-innovation-in-advanced-materials… the need for a “ governance structure to manage the risk and sustainability of advanced materials ”, and …
Publication date: 06-12-2025