The Dutch National Institute for Public Health and the Environment (RIVM) is actively involved in research and policy advice towards the replacement, reduction and refinement (the 3R principle) of animal use in regulatory safety assessment of chemicals and medicines.
An important task of RIVM is to stimulate regulatory acceptance and implementation in legal frameworks of 3R methods and approaches that can be used for the safety assessment of chemicals and medicines. These 3R methods and approaches need to be as robust (reliable, reproducible, relevant, etc.) as the methods that are currently used. In addition, these approaches need to provide the necessary information needed for the intended regulatory purpose.
Would you like to be kept informed about RIVM activities on 3Rs? Subscribe to the RIVM newsletter 3R Quarterly.