Publicaties Flemming Cassee, inhalatietoxicoloog bij het RIVMRijksinstituut voor Volksgezondheid en Milieu.

International peer reviewed journals

  1. Alberg T, Cassee FR, Groeng ECEuropean Commission, Dybing E, Lovik M. Fine ambient particles from various sites in europe exerted a greater IgE adjuvant effect than coarse ambient particles in a mouse model. J Toxicol Environ Health A. 2009;72(1):1-13.

  2. Ayres JG, Borm P, Cassee FR, Castranova V, Donaldson K, Ghio A, et al. Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement. Inhal Toxicol. 2008 Jan;20(1):75-99.

  3. Bagate K, Meiring JJ, Cassee FR, Borm PJ. The effect of particulate matter on resistance and conductance vessels in the rat. Inhal Toxicol. 2004 Jun;16(6-7):431-6.

  4. Bagate K, Meiring JJ, Gerlofs-Nijland ME, Cassee FR, Borm PJ. Signal transduction pathways involved in particulate matter induced relaxation in rat aorta--spontaneous hypertensive versus Wistar Kyoto rats. Toxicol In Vitro. 2006 Feb;20(1):52-62.

  5. Bagate K, Meiring JJ, Gerlofs-Nijland ME, Cassee FR, Wiegand H, Osornio-Vargas A, et al. Ambient particulate matter affects cardiac recovery in a Langendorff ischemia model. Inhal Toxicol. 2006 Aug;18(9):633-43.

  6. Bagate K, Meiring JJ, Gerlofs-Nijland ME, Vincent R, Cassee FR, Borm PJ. Vascular effects of ambient particulate matter instillation in spontaneous hypertensive rats. Toxicol Appl Pharmacol. 2004 May 15;197(1):29-39.

  7. Becker S, Soukup JMJoint meeting, Sioutas C, Cassee FR. Response of human alveolar macrophages to ultrafine, fine, and coarse urban air pollution particles. Exp Lung Res. 2003 Jan-Feb;29(1):29-44.

  8. Behndig AF, Mudway IS, Brown JL, Stenfors N, Helleday R, Duggan ST, et al. Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans. EurErasmus Universiteit Rotterdam Respir J. 2006 Feb;27(2):359-65.

  9. Biswas S, Verma V, Schauer JJ, Cassee FR, Cho AKacellulair kinkhoest, Sioutas C. Oxidative potential of semi-volatile and non volatile particulate matter (PM) from heavy-duty vehicles retrofitted with emission control technologies. Environ Sci Technol. 2009 May 15;43(10):3905-12.

  10. Boogaard H, Janssen NA, Fischer PH, Kos GPgeneral practitioner, Weijers EP, Cassee FR, et al. Contrasts in oxidative potential and other particulate matter characteristics collected near major streets and background locations. Environ Health Perspect. 2012 Feb;120(2):185-91.

  11. Boogaard H, Janssen NA, Fischer PH, Kos GP, Weijers EP, Cassee FR, van der Zee SC, de Hartog JJ, Brunekreef B, Hoek G. Contrasts in oxidative potential and other particulate matter characteristics collected near major streets and background locations.Environ Health Perspect. 2012 Feb;120(2):185-91.

  12. Boogaard H, Janssen NA, Fischer PH, Kos GP, Weijers EP, Cassee FR, van der Zee SC, de Hartog JJ, Meliefste K, Wang M, Brunekreef B, Hoek G. Impact of low emission zones and local traffic policies on ambient air pollution concentrations.Sci Total Environ. 2012 Oct 1;435-436:132-40.

  13. Brandsma CA, Hylkema MN, Luinge MA, Geerlings M, Klok PA, Cassee FR, et al. Nitrogen dioxide exposure attenuates cigarette smoke-induced cytokine production in mice. Inhal Toxicol. 2008 Jan;20(2):183-9.

  14. Cassee FR, Arts JH, Fokkens PH, Spoor SM, Boere AJ, van Bree L, et al. Pulmonary effects of ultrafine and fine ammonium salts aerosols in healthy and monocrotaline-treated rats following short-term exposure. Inhal Toxicol. 2002 Dec;14(12):1215-29.

  15. Cassee FR, Arts JH, Groten JP, Feron VJ. Sensory irritation to mixtures of formaldehyde, acrolein, and acetaldehyde in rats. Arch Toxicol. 1996;70(6):329-37.

  16. Cassee FR, Boere AJ, Bos J, Fokkens PH, Dormans JA, van Loveren H. Effects of diesel exhaust enriched concentrated PM2.5 in ozone preexposed or monocrotaline-treated rats. Inhal Toxicol. 2002 Jul;14(7):721-43.

  17. Cassee FR, Boere AJ, Fokkens PH, Leseman DL, Sioutas C, Kooter IM, et al. Inhalation of concentrated particulate matter produces pulmonary inflammation and systemic biological effects in compromised rats. J Toxicol Environ Health A. 2005 May 28;68(10):773-96.

  18. Cassee FR, Campbell A, Boere AJ, McLean SG, Duffin R, Krystek P, Gosens I, Miller MRantimicrobial resistance. The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice. Environ Res. 2012 May;115:1-10.

  19. Cassee FR, de Burbure CY, Rambali B, Vleeming W, van de Kuil A, van Steeg H, et al. Subchronic inhalation of mixtures of cigarette smoke constituents in Xpa-/-p53+/- knock-out mice: a comparison of intermittent with semi-continuous exposure to acetaldehyde, formaldehyde, and acrolein. Food Chem Toxicol. 2008 Feb;46(2):527-36.

  20. Cassee FR, Feron VJ. Biochemical and histopathological changes in nasal epithelium of rats after 3-day intermittent exposure to formaldehyde and ozone alone or in combination. Toxicol Lett. 1994 Jun;72(1-3):257-68.

  21. Cassee FR, Groten JP, Feron VJ. Changes in the nasal epithelium of rats exposed by inhalation to mixtures of formaldehyde, acetaldehyde, and acrolein. Fundam Appl Toxicol. 1996 Feb;29(2):208-18.

  22. Cassee FR, Groten JP, van Bladeren PJ, Feron VJ. Toxicological evaluation and risk assessment of chemical mixtures. Crit RevRevalidatiecentra Toxicol. 1998 Jan;28(1):73-101.

  23. Cassee FR, Muijser H, Duistermaat E, Freijer JJ, Geerse KB, Marijnissen JC, et al. Particle size-dependent total mass deposition in lungs determines inhalation toxicity of cadmium chloride aerosols in rats. Application of a multiple path dosimetry model. Arch Toxicol. 2002 Jun;76(5-6):277-86.

  24. Cassee FR, Stenhuis WH, Groten JP, Feron VJ. Toxicity of formaldehyde and acrolein mixtures: in vitro studies using nasal epithelial cells. Exp Toxicol Pathol. 1996 NovNederlandse Orthopaedische Vereniging;48(6):481-3.

  25. Cassee FR, van Balen EC, Singh C, Green D, Muijser H, Weinstein J, et al. Exposure, health and ecological effects review of engineered nanoscale cerium and cerium oxide associated with its use as a fuel additive. Crit Rev Toxicol. 2011 Mar;41(3):213-29.

  26. Cassee FR. Reflections on the scope and the future of Particle and Fibre Toxicology. Part Fibre Toxicol. 2011;8:13.

  27. Cheung KL, Polidori A, Ntziachristos L, Tzamkiozis T, Samaras Z, Cassee FR, et al. Chemical characteristics and oxidative potential of particulate matter emissions from gasoline, diesel, and biodiesel cars. Environ Sci Technol. 2009 Aug 15;43(16):6334-40.

  28. Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation.Eur Heart J. 2011 Nov;32(21):2660-71.

  29. Feron VJ, Cassee FR, Groten JP, van Vliet PWpartnerwaarschuwing, van Zorge JA. International issues on human health effects of exposure to chemical mixtures. Environ Health Perspect. 2002 Dec;110 Suppl 6:893-9.

  30. Feron VJ, Cassee FR, Groten JP. Toxicology of chemical mixtures: international perspective. Environ Health Perspect. 1998 Dec;106 Suppl 6:1281-9.

  31. Feron VJ, Groten JP, Jonker D, Cassee FR, van Bladeren PJ. Toxicology of chemical mixtures: challenges for today and the future. Toxicology. 1995 Dec 28;105(2-3):415-27.

  32. Feron VJ, Groten JP, van Zorge JA, Cassee FR, Jonker D, van Bladeren PJ. Toxicity studies in rats of simple mixtures of chemicals with the same or different target organs. Toxicol Lett. 1995 Dec;82-83:505-12.

  33. Feron VJ, Til HP, de Vrijer F, Woutersen RA, Cassee FR, van Bladeren PJ. Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. Mutat Res. 1991 Mar-Apr;259(3-4):363-85.

  34. Feron VJ, Woutersen RA, Arts JH, Cassee FR, de Vrijer F, van Bladeren PJ. Safety evaluation of the mixture of chemicals at a specific workplace: theoretical considerations and a suggested two-step procedure. Toxicol Lett. 1995 Feb;76(1):47-55.

  35. Fischer PH, Marra M, Ameling CBconsultatiebureau, Janssen N, Cassee FR. Trends in relative risk estimates for the association between air pollution and mortality in The Netherlands, 1992-2006. Environ Res. 2011 Jan;111(1):94-100.

  36. Freney EJ, Heal MR, Donovan RJ, Mills NL, Donaldson K, Newby DE, et al. A single-particle characterization of a mobile Versatile Aerosol Concentration Enrichment System for exposure studies. Part Fibre Toxicol. 2006;3:8.

  37. Geraets L, Oomen AG, Schroeter JDCreutzfeldt-Jakob, Coleman VA, Cassee FR. Tissue Distribution of Inhaled Micro- and Nano-sized Cerium Oxide Particles in Rats: Results from a 28-day Exposure Study. Toxicol Sci. 2012 Mar 19.

  38. Geraets L, Oomen AG, Schroeter JD, Coleman VA, Cassee FR. Tissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure study. Toxicol Sci. 2012 Jun;127(2):463-73.

  39. Gerlofs-Nijland ME, Boere AJ, Leseman DL, Dormans JA, Sandstrom T, Salonen RO, et al. Effects of particulate matter on the pulmonary and vascular system: time courseClimate and Ozone change effects on Ultraviolet radiation and risks using Remote sensing based System Evaluations in spontaneously hypertensive rats. Part Fibre Toxicol. 2005 Mar 24;2(1):2.

  40. Gerlofs-Nijland ME, Dormans JA, Bloemen HJ, Leseman DL, John A, Boere F, et al. Toxicity of coarse and fine particulate matter from sites with contrasting traffic profiles. Inhal Toxicol. 2007 Oct;19(13):1055-69.

  41. Gerlofs-Nijland ME, Rummelhard M, Boere AJ, Leseman DL, Duffin R, Schins RPResponsible Person, et al. Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents. Environ Sci Technol. 2009 Jul 1;43(13):4729-36.

  42. Gerlofs-Nijland ME, Totlandsdal AI, Kilinc E, Boere AJ, Fokkens PH, Leseman DL, et al. Pulmonary and cardiovascular effects of traffic-related particulate matter: 4-week exposure of rats to roadside and diesel engine exhaust particles. Inhal Toxicol. 2010 Dec;22(14):1162-73.

  43. Gerlofs-Nijland ME, van Berlo D, Cassee FR, Schins RP, Wang K, Campbell A. Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain. Part Fibre Toxicol. 2010;7:12.

  44. Gosens I, Post JA, de la Fonteyne LJ, Jansen EH, GeusGeologische Dienst voor Denemarken en Groenland JW, Cassee FR, et al. Impact of agglomeration state of nano- and submicron sized gold particles on pulmonary inflammation. Part Fibre Toxicol. 2010;7(1):37.

  45. Guastadisegni C, Kelly FJ, Cassee FR, Gerlofs-Nijland ME, Janssen NA, Pozzi R, et al. Determinants of the proinflammatory action of ambient particulate matter in immortalized murine macrophages. Environ Health Perspect. 2010 Dec;118(12):1728-34.

  46. Hagens WI, Oomen AG, de Jong WH, Cassee FR, Sips AJ. What do we (need to) know about the kinetic properties of nanoparticles in the body? Regul Toxicol Pharmacol. 2007 Dec;49(3):217-29.

  47. Halatek T, Stepnik M, Stetkiewicz J, Krajnow A, Kur B, Szymczak W, et al. The inflammatory response in lungs of rats exposed on the airborne particles collected during different seasons in four European cities. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2011 Nov;46(13):1469-81.

  48. Halatek T, Stepnik M, Stetkiewicz J, Krajnow A, Kur B, Szymczak W, Rydzynski K, Dybing E, Cassee FR. The inflammatory response in lungs of rats exposed on the airborne particles collected during different seasons in four European cities. J Environ Sci Health A Tox Hazard. Subst Environ Eng. 2011;46(13):1469-81.

  49. Happo MSmicrosoft, Salonen RO, Halinen AI, Jalava PI, Pennanen AS, Dormans JA, et al. Inflammation and tissue damage in mouse lung by single and repeated dosing of urban air coarse and fine particles collected from six European cities. Inhal Toxicol. 2010 Apr;22(5):402-16.

  50. Hassing C, Twickler M, Brunekreef B, Cassee F, Doevendans P, Kastelein J, et al. Particulate air pollution, coronary heart disease and individual risk assessment: a general overview. Eur J Cardiovasc Prev Rehabil. 2009 Feb;16(1):10-5.

  51. Hassing HC, Twickler TBtuberculose, Kastelein JJ, Cramer MJ, Cassee FR. Air pollution as noxious environmental factor in the development of cardiovascular disease. Neth J MedMedical Exposure Directive. 2009 Apr;67(4):116-21.

  52. Hetland RBRobertson-Berger, Cassee FR, Lag M, Refsnes M, Dybing E, Schwarze PE. Cytokine release from alveolar macrophages exposed to ambient particulate matter: heterogeneity in relation to size, city and season. Part Fibre Toxicol. 2005 Aug 17;2:4.

  53. Hetland RB, Cassee FR, Refsnes M, Schwarze PE, Lag M, Boere AJ, et al. Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions. Toxicol In Vitro. 2004 Apr;18(2):203-12.

  54. Hoogervorst EM, de Vries A, Beems RB, van Oostrom CT, Wester PW, Vosvluchtige organische stoffen JG, et al. Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNAdeoxyribonucleic acid repair-deficient Xpa mice. Carcinogenesis. 2003 Mar;24(3):613-9.

  55. Hurkmans CW, Meijer GJ, van Vliet-Vroegindeweij C, van der Sangen MJ, Cassee J. High-dose simultaneously integrated breast boost using intensity-modulated radiotherapy and inverse optimization. Int J Radiat Oncol Biol Phys. 2006 Nov 1;66(3):923-30.

  56. Jalava PI, Hirvonen MR, Sillanpaa M, Pennanen AS, Happo MS, Hillamo R, et al. Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line. Inhal Toxicol. 2009 Oct;21(12):994-1006.

  57. Janssen NA, Hoek G, Simic-Lawson M, Fischer P, Bree LV, Brink HT, et al. Black carbon as an Additional Indicator of the Adverse Health Effects of Airborne Particles Compared to PM10fijnstof and PM2.5. Environ Health Perspect. 2011 Aug 2.

  58. Janssen NA, Hoek G, Simic-Lawson M, Fischer P, van Bree L, ten Brink H, et al. Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5. Environ Health Perspect. 2011 Dec;119(12):1691-9.

  59. Janssen NA, Hoek G, Simic-Lawson M, Fischer P, van Bree L, ten Brink H, Keuken M, Atkinson RW, Anderson HRhazard ratio, Brunekreef B, Cassee FR. Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5.Environ Health Perspect. 2011 Dec;119(12):1691-9.. Review.

  60. Kilinc E, Van Oerle R, Borissoff JI, Oschatz C, Gerlofs-Nijland ME, Janssen NA, et al. Factor XII activation is essential to sustainSustainable tailored integrated care for older people in Europe the procoagulant effects of particulate matter. J Thromb Haemost. 2011 Jul;9(7):1359-67.

  61. Kilinç E, Van Oerle R, Borissoff JI, Oschatz C, Gerlofs-Nijland ME, Janssen NA, Cassee FR, Sandström T, Renné T, Ten Cate H, Spronk HM. Factor XII activation is essential to sustain the procoagulant effects of particulate matter.J Thromb Haemost. 2011 Jul;9(7):1359-67. doi: 10.1111/j.1538-7836.2011.04280.x.

  62. Kleinman MT, Sioutas C, Chang MCmedisch centrum, Boere AJ, Cassee FR. Ambient fine and coarse particle suppression of alveolar macrophage functions. Toxicol Lett. 2003 Feb 3;137(3):151-8.

  63. Knol AB, de Hartog JJ, Boogaard H, Slottje P, van der Sluijs JP, Lebret E, et al. Expert elicitation on ultrafine particles: likelihood of health effects and causal pathways. Part Fibre Toxicol. 2009;6:19.

  64. Kocbach A, Li Y, Yttri KE, Cassee FR, Schwarze PE, Namork E. Physicochemical characterisation of combustion particles from vehicle exhaust and residential wood smoke. Part Fibre Toxicol. 2006;3:1.

  65. Kooter I, Pennings J, Opperhuizen A, Cassee F. Gene expression pattern in spontaneously hypertensive rats exposed to urban particulate matter (EHC-93). Inhal Toxicol. 2005 Jan;17(1):53-65.

  66. Kooter IM, Boere AJ, Fokkens PH, Leseman DL, Dormans JA, Cassee FR. Response of spontaneously hypertensive rats to inhalation of fine and ultrafine particles from traffic: experimental controlled study. Part Fibre Toxicol. 2006;3:7.

  67. Kooter IM, Frederix K, Spronk HM, Boere AJ, Leseman DL, van Steeg H, et al. Lung inflammation and thrombogenic responses in a time course study of Csb mice exposed to ozone. J Appl Toxicol. 2008 Aug;28(6):779-87.

  68. Kooter IM, Gerlofs-Nijland ME, Boere AJ, Leseman DL, Fokkens PH, Spronk HM, et al. Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats. J Toxicol. 2010;2010:206057.

  69. Kooter IM, Pennings JL, Fokkens PH, Leseman DL, Boere AJ, Gerlofs-Nijland ME, et al. Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status. J Appl Physiol. 2007 Mar;102(3):1185-92.

  70. Langrish JP, Li X, Wang S, Lee MM, Barnes GDGezondheidsdienst voor Dieren, Miller MR, et al. Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease. Environ Health Perspect. 2011 Mar;120(3):367-72.

  71. Langrish JP, Mills NL, Chan JK, Leseman DL, Aitken RJ, Fokkens PH, et al. Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. Part Fibre Toxicol. 2009;6:8.

  72. Lippmann M, Cassee FR, Costa DL, Costantini M, van Erp AM, Gordon T. International Workshop on the Design and Analysis of Experimental Studies using PM Concentrator Technologies, Boston, May 5, 2004. Inhal Toxicol. 2005 Dec 15;17(14):839-50.

  73. Lucking AJ, Lundback M, Barath SL, Mills NL, Sidhu MK, Langrish JP, et al. Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men. Circulation. 2011 Apr 26;123(16):1721-8.

  74. Lucking AJ, Lundback M, Mills NL, Faratian D, Barath SL, Pourazar J, et al. Diesel exhaust inhalation increases thrombus formation in man. Eur Heart J. 2008 Dec;29(24):3043-51.

  75. Mills NL, Amin N, Robinson SD, Anand A, Davies J, Patel D, et al. Do inhaled carbon nanoparticles translocate directly into the circulation in humans? Am J Respir Crit Care Med. 2006 Feb 15;173(4):426-31.

  76. Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, et al. Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med. 2009 Jan;6(1):36-44.

  77. Mills NL, Miller MR, Lucking AJ, Beveridge J, Flint L, Boere AJ, et al. Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation. Eur Heart J. 2011 Nov;32(21):2660-71.

  78. Mills NL, Miller MR, Lucking AJ, Beveridge J, Flint L, Boere AJ, Fokkens PH, Boon NA, Sandstrom T, Blomberg A, Duffin R, Donaldson K, Hadoke PW, Cassee FR, Newby DE.

  79. Mills NL, Robinson SD, Fokkens PH, Leseman DL, Miller MR, Anderson D, et al. Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease. Environ Health Perspect. 2008 Jun;116(6):709-15.

  80. Neurobehavioral effects of exposure to traffic-related air pollution and transportation noise in primary schoolchildren. van Kempen E, Fischer P, Janssen N, Houthuijs D, van Kamp I, Stansfeld S, Cassee F. Environ Res. 2012 May;115:18-25.

  81. Rudez G, Janssen NA, Kilinc E, Leebeek FW, Gerlofs-Nijland ME, Spronk HM, et al. Effects of ambient air pollution on hemostasis and inflammation. Environ Health Perspect. 2009 Jun;117(6):995-1001.

  82. Sandstrom T, Cassee FR, Salonen R, Dybing E. Recent outcomes in European multicentre projects on ambient particulate air pollution. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):261-8.

  83. Schlesinger RB, Cassee F. Atmospheric secondary inorganic particulate matter: the toxicological perspective as a basis for health effects risk assessment. Inhal Toxicol. 2003 Mar;15(3):197-235.

  84. Schwarze PE, Ovrevik J, Hetland RB, Becher R, Cassee FR, Lag M, et al. Importance of size and composition of particles for effects on cells in vitro. Inhal Toxicol. 2007;19 Suppl 1:17-22.

  85. Steenhof M, Gosens I, Strak M, Godri KJ, Hoek G, Cassee FR, et al. In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project. Part Fibre Toxicol. 2011 Sep 2;8(1):26.

  86. Steenhof M, Gosens I, Strak M, Godri KJ, Hoek G, Cassee FR, et al. In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project. Part Fibre Toxicol. 2011;8:26.

  87. Steenhof M, Gosens I, Strak M, Godri KJ, Hoek G, Cassee FR, Mudway IS, Kelly FJ, Harrison RMrisicomanagement, Lebret E, Brunekreef B, Janssen NA, Pieters RH. In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project. Part Fibre Toxicol. 2011 Sep 2;8:26.

  88. Steerenberg P, Verlaan A, De Klerk A, Boere A, Loveren H, Cassee F. Sensitivity to ozone, diesel exhaust particles, and standardized ambient particulate matter in rats with a listeria monocytogenes-induced respiratory infection. Inhal Toxicol. 2004 May;16(5):311-7.

  89. Steerenberg PA, van Amelsvoort L, Lovik M, Hetland RB, Alberg T, Halatek T, et al. Relation between sources of particulate air pollution and biological effect parameters in samples from four European cities: an exploratory study. Inhal Toxicol. 2006 May;18(5):333-46.

  90. Steerenberg PA, Withagen CEConformité Européenne, van Dalen WJ, Dormans JA, Cassee FR, Heisterkamp SHsmall hydrophobic, et al. Adjuvant activity of ambient particulate matter of different sites, sizes, and seasons in a respiratory allergy mouse model. Toxicol Appl Pharmacol. 2004 Nov 1;200(3):186-200.

  91. Steerenberg PA, Withagen CE, van Dalen WJ, Dormans JA, Heisterkamp SH, van Loveren H, et al. Dose dependency of adjuvant activity of particulate matter from five European sites in three seasons in an ovalbumin-mouse model. Inhal Toxicol. 2005 Mar;17(3):133-45.

  92. Strak M, Janssen NA, Godri KJ, Gosens I, Mudway IS, Cassee FR, Lebret E, Kelly FJ, Harrison RM, Brunekreef B, Steenhof M, Hoek G. Respiratory Health Effects of Airborne Particulate Matter: The Role of Particle Size, Composition, and Oxidative Potential-The RAPTES Project.Environ Health Perspect. 2012 Aug;120(8):1183-9.

  93. Totlandsdal AI, Cassee FR, Schwarze P, Refsnes M, Lag M. Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells. Part Fibre Toxicol. 2010;7:41.

  94. Ulrich MM, Alink GM, Kumarathasan P, Vincent R, Boere AJ, Cassee FR. Health effects and time course of particulate matter on the cardiopulmonary system in rats with lung inflammation. J Toxicol Environ Health A. 2002 Oct 25;65(20):1571-95.

  95. van Berlo D, Albrecht C, Knaapen AM, Cassee FR, Gerlofs-Nijland ME, Kooter IM, et al. Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain. Arch Toxicol. 2010 Jul;84(7):553-62.

  96. Verma V, Polidori A, Schauer JJ, Shafer MM, Cassee FR, Sioutas C. Physicochemical and toxicological profiles of particulate matter in Los Angeles during the October 2007 southern California wildfires. Environ Sci Technol. 2009 Feb 1;43(3):954-60.

  97. Wessels A, Van Berlo D, Boots AW, Gerloff K, Scherbart AM, Cassee FR, et al. Oxidative stress and DNA damage responses in rat and mouse lung to inhaled carbon nanoparticles. Nanotoxicology. 2011 Mar;5(1):66-78.

  98. Yang TJ, Elkhuizen PH, Minkema D, Heemsbergen W, van Mourik AM, Cassee J, et al. Clinical factors associated with seroma volume reduction in breast-Conserving Therapy for early-stage breast cancer: a multi-institutional analysis. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1325-32.

 

Reports


  1. Application of principal component analysis to time series of daily air pollution and mortality . Quant C -2003 RIVMRijksinstituut voor Volksgezondheid en Milieu Quant C, Fischer P, Buringh E, Ameling C, Houthuijs D, Cassee F Rapport 650010035

  2. Cardiovascular disease as risk factor for air pollution health effects. Validation of a transgenic rodent model for hypertension Gosens I, Boere AJF, Wong A, Fokkens PHB, Cassee FR 2009 RIVM rapport 630196001

  3. Chemical characterization and source apportionment estimates of particulate matter collected within the framework of EUEuropean Union project HEPMEAP. Bloemen HJT, Gerlofs-Nijland ME, Janssen NAH, Sandstrom T, Bree L van, Cassee FR -2005 RIVM Rapport 863001002

  4. Composition and sources of fine particulate matter (PM2.5) in the Netherlands [ De samenstelling en bronnen van fijn stof (PM2,5fijnstof) in Nederland ] Bloemen HJT, Mooibroek D, Cassee FR, Putten EM van, 2008. RIVM rapport 863001007

  5. Development of a model for human and rat airway particle deposition: implications for risk assessment . Cassee FR, Freijer JI, Subramaniam R, Asghararian B, Miller FJ, Bree L van, Rombout PJA-1999 RIVM Rapport 650010018

  6. Een pilot-studie naar de bruikbaarheid van fysiologische markers voor psychologische stress en gezondheidseffecten. De variatie van en de invloeden op cortisol, serotonine en neopterine in urine bij vrijwilligers . Cassee FR, Franssen EAMEnvironmental Assessment Module, Amsterdam JGC van, Houthuijs DJM -1999 RIVM Rapport 624029002

  7. Fijn stof nader bekeken . Buijsman E, Beck JP, Bree L van, Cassee FR, Koelemeijer RBA, Matthijsen J, Thomas R, Wieringa K -2005 RIVM Rapport 500037008

  8. From concentration to dose: factors influencing airborne particulate matter deposition in humans and rats . Winter-sorkina R de -2002 RIVM Winter-sorkina R de, Cassee FR Rapport 650010031

  9. Health effects of addition and combustion of fuel additives: Quick scan and deepening of a selective additive set. Gerlofs-Nijland ME, Groenewegen L, Cassee FR, 2008 RIVM rapport 630160001

  10. Health effects of addition and combustion of fuel additives: Quick scan and deepening of a selective additive set Gerlofs-Nijland ME, Groenewegen L, Cassee FR, 2008 RIVM rapport 630160001

  11. Health effects of moped emissions. Gerlofs-Nijland ME, Mathijssen EAM, Jongeneel WPwork package, Cassee FR RIVM Rapport 630315001

  12. Health effects of wood smoke : A literature review Hagens WI, van Overveld AJP, Fischer PH, Gerlofs-Nijland ME, Cassee FR RIVM Rapport 609300027

  13. Health Risks in relation to air quality, especially particulate matter. Interim report . Rombout PJA -2000 RIVM Rombout PJA, Bloemen HJTh, Bree L van, Buring E, Cassee FR, Fischer PH, Freijer JL, Kruize H, Marra M, Opperhuizen Rapport 650010020

  14. Immune effects of respiratory exposure to fragrance chemicals. Ezendam J, de Klerk A, Cassee FR, Fokkens PHB, Park MVDZ, van Loveren H, de Jong WH RIVM Rapport 340301001

  15. Impact of agglomeration state of gold particles on pulmonary toxicity Gosens I, Leseman DLAC, de la Fonteyne LJJ, Geus JW, Post JA, Jansen EHJM, Boere AJF, Cassee FR, de Jong WH RIVM Rapport 340370002

  16. Interpretatie en implicaties van de door de Europese Commissie aanbevolen definitie van nanomaterialen Bleeker EAJ, Cassee FR, Geertsma RE, de Jong WH, Heugens EHW, Koers-Jacquemijns M, van de Meent D, Oomen AG, Popma J, Rietveld AG, Wijnhoven SWP. RIVM Rapport 601358001

  17. Invloed van de afstand tot een drukke verkeersweg op de lokale luchtkwaliteit en de gezondheid: een quick scan - Fischer PH, Marra M, Wesseling J, Cassee FR 2008 briefrapport 863001005

  18. Modeling of particulate matter deposition in the human airways. Freijer JI, Cassee FR, Bree L van -1997 RIVM Rapport 624029001

  19. Monitoring Black Smoke? Its value for monitoring the impact of abatement measures [ Monitoring Zwarte Rook? - De waarde voor het volgen van de invloed van beleidsmaatregelen Bloemen HJT, Meulen A van der, Mooibroek D, Cassee FR , 2007 RIVM rapport: 863001004

  20. Multiple Path Particle Deposition Model (MPPDep Version 1.11). A model for human and rat airway particle deposition . Freijer JI, Cassee FR, Subramaniam R, Asghararian B, Anjilvel S, Miller FJ, Bree L van, Rombout PJA -1999 RIVM Rapport 650010019

  21. Multiple Path Particle Dosimetry model (MPPD v1.0): A model for human and rat airway particle dosimetry . Price OT -2002 RIVM Price OT, Asgharian B, Miller FJ, Cassee FR, Winter-Sorkina R de Rapport 650010030

  22. Nanotechnologie in perspectief. Risico's voor mens en milieu [ Nanotechnology in perspective. Risks for man and the environment ] Geertsma RE, Roszek BR, Herberts CA, Brouwer N, Wijnhoven SWP, Engelen JGM van, Dekkers S, Meent D van der, Peijnenburg WJGM, Linders JBHJ, Heugens EHW, Cassee FR, Jong WH de, Roels JM, Brouwer DH, Nieboer-op de Weegh MJ, Sandt JJM van de, Kampers FWH. RIVM Rapport 601785002

  23. Particulate Matter: a closer look . Buijsman E, Beck JP, Bree L van, Cassee FR, Koelemeijer RBA, Matthijsen J, Thomas R, Wieringa K -2005 RIVM Rapport 500037011

  24. Progress report on PM toxicity using concentrated ambient particulate matter (CAPs) . Cassee FR -2001 RIVM Rapport 650010021

  25. Respiratory Allergy and Inflammation Due to Ambient Particles (RAIAP) Collection of Particulate Matter samples from 5 European sites with High Volume Cascade Impactors . Cassee FR -2003 RIVM Rapport 863001001

  26. Risk assessment for populations during inhalation exposure as a result of catastrophes. Bloemen HJTh, Cassee FR. RIVM rapport 630110002

  27. Toxicity of Ambient Air PM10. A critical review of potentially causative PM properties and mechanisms associated with health effects . Bree L van -2000 RIVM Bree L van, Cassee FR Rapport 650010015

  28. Toxicity of Ambient Particulate Matter (PM10) I. Acute toxicity study in asthmatic mice following 3-day exposure to ultrafine and fine ammonium bisulfate, a model compound for secondary aerosol fraction of PM10 . Cassee FR, Dormans JAMAJournal of the American Medical Association, Loveren H van, Bree L van, Rombout PJA -1999 RIVM Rapport 650010010

  29. Toxicity of Ambient Particulate Matter II. Acute toxicity study in asthmatic mice following 3-day exposure to fine ammonium ferrosulfate, a model compound for secondary aerosol of PM10 . Cassee FR, Dormans JAMA, Loveren H van, Bree L van, Rombout PJA -1999 RIVM Rapport 650010011

  30. Toxicity of Ambient Particulate Matter IVhuman immunodeficiency virus: Acute toxicity study in pulmonary hypertensive rats after exposure to model compounds for the secondary aerosol fraction of PM10 - ammonium bisulfate, ferrosulfate and nitrate . Cassee FR, Boere AJF, Fokkens PHB, Dormans JAMA, Bree L van, Rombout PJA -1999 RIVM Rapport 650010016

  31. Toxicity of Ambient Particulate Matter. III. Acute toxicity study in asthmatic mice following 3-day exposure to ultrafine and fine ammonium nitrate, a model compound for secondary aerosol fraction of PM10. Cassee FR, Dormans JAMA, Loveren H van, Bree L van, Rombout PJA -1998 RIVM Rapport 650010013

 

Book contributions

  1. F.R. Cassee, J. Sühnel, J.P. Groten and V.J. Feron, Toxicology of chemical mixtures (Second ed.) In: B. Ballantyne, T. Marrs and T. Syversen, Editors, General and Applied Toxicology vol. 1, Macmillan Reference Ltd., London (1999), pp. 303–319.

  2. J.P. Groten, F.R. Cassee, P.J. van Bladeren, C. DeRosa and V.J. Feron, Mixtures In: H. Marquardt, S.G. Schäfer, R. McClellan and F. Welsch, Editors, Toxicology, Academic Press, San Diego (1999), pp. 257–270.

  3. Cardiovascular Effects of Inhaled Fine and Nano-sized Particles, Edited by FR Cassee, NL Mills and DE Newby, 1stEdition - January 2011. 2011. 586 Pages, ISBN-13: 978-0-470-43353-9 - John Wiley & Sons

  4. Anique Driessen, Björn Crüts, Ludo van Etten, Anica Crüts , Paul Fokkens, Flemming Cassee, and Paul J.A. Borm. Short term exposure to nanoparticle-rich diesel engine exhaust causes changes in brain activity but not in cognitive performance in human volunteers .In: Nanoformulation (Tiddy, GJT & Tan, BH, eds), pp 243-255. RSC Publishing, Cambridge, UKUnited Kingdom, 2012. ISBN: 978-1-84973-524-7