|Auteur||NAT van der MaasIF Zonnenberg-HoffS DavidN MoorerM BultsC WesseloPE Vermeer-de BondtB OostvogelsTAJ PHaff|
De bijwerkingenbewaking van het Rijksvaccinatieprogramma over 2007 liet een duidelijke afname zien van het aantal meldingen. In 2007 zijn in totaal 995 meldingen ontvangen. Hiervan werd 72% als bijwerking van de vaccinaties beschouwd. De rest (28%) was niet door de vaccinatie veroorzaakt. Het aantal bijwerkingen moet in relatie worden gezien tot de 1,4 miljoen vaccinatiemomenten en de bijna 7 miljoen vaccincomponenten die daarbij worden toegediend.
Adverse events following immunization (AEFI) in the National Vaccination Programme of the Netherlands (RVP) have been monitored through an enhanced passive surveillance system by the National Institute for Public Health and the Environment (RIVM) since 1962. From 1984 until 2003 evaluation has been done in close collaboration with the Health Council. An RIVM expert panel continued the reassessment of selected adverse events from 2004 onwards. Reports were received mainly from Child Health Care professionals, primarily by telephone through the operating service for information and advice on vaccines and vaccinations. Further data have been obtained, if necessary, from parents, general practitioners, paediatricians and other professionals. After supplementation and verification of data a (working) diagnosis is made and causality assessed. In this annual report on 2007 an overview of all reported AEFI is presented with classification according to case definitions and causality. Trend analysis, reporting bias, background rates of specific events and possible pathophysiology of symptoms are discussed. On a total of over 1.4 million vaccination dates 995 AEFI were reported. In 72% (710) of the classifiable events a possible causal relation with vaccination was established. These concerned major adverse reactions in 50% and minor adverse reactions in 50% of the reports. Of the reported adverse events 28% (280) were considered chance occurrences.
|Year of Publication||
|Number of Pages||