In this project, we assess the impact of immediate initiation of combination antiretroviral therapy (cART), frequent testing, partner notification, and pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in the Netherlands. We examine their impact on the transmission of HIV and the transmission of other sexually transmitted infections (STI), with N. gonorrhoea (NG) as example. Furthermore, we investigate the cost-effectiveness of these strategies.