Fact sheets WP4-WP6

To support the dissemination of the results of the NANoREG project, the NANoREG deliverables have been summarised in fact sheets. The fact sheet not only summarises the results but also briefly describes the aim and context of the work that has been carried out.

No

Name of the deliverable/factsheet

D4.01

Initiate and perform in-life long-term inhalation study

D4.03

Lung burden and particle detection and quantification in olfactory bulbs, blood- subacute exposure

D4.04

Organ burden and particle detection pattern in other organs after subacute exposure

D4.05

Lung burden and particle detection and quantification in olfactory bulbs - chronic exposure

D4.06

Organ burden, faeces analyses and particle detection pattern in other organs after chronic exposure

D4.07

Histopathological evaluation (all organs) Immunohistochemical detection of local and systemic genotoxicity

D4.10

Particle distribution of MNM in hepatic and liver cell models

D4.11

Identification of hazards and NOAELs for amorphous silica after subchronic oral exposure

D4.12

Accumulation potential and aquatic toxicity of relevant groups of nanomaterials and product formula

D4.14

Prenatal toxicity study with cerium oxide and MWCNT carbon nanotubes

D4.15

Protocol for inhalation exposure and choice of biological relevant endpoints

D4.16

Immunotoxic and genotoxic effects after short-term inhalation of fibrous nanomaterials

D4.17

Development of PBPK models

 

D5.01

Report on identification and setting of categorization, read-across, and extra/interpolation criteria

D5.02

Development of a solubility testing procedure

D5.03

In vitro screening methodology for absorption or crossing of other barriers

D5.04

In vitro screening methodology to evaluate toxicity by inhalation

D5.05

Report on cell type and in vitro-in vivo correlation studies for inhalation toxicity

D5.06

Identification and optimization of the most suitable in vitro methodology

D5.07

Develop a rapid high throughput screening methodology to evaluate NM toxicity

D5.08

Decision tree for risk assessment of MNMs

 

D6.01

Proposal to monitor innovations in new nanomaterials and their applications

D6.02

Inventory of safety assessment issues and new approaches to research and governance

D6.03

Comparison on toxicity testing in drug development and in present MNMs safety testing

D6.04

Inventory of existing regulatory accepted toxicity tests applicable for safety screening of MNMs

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