NNN (N’-Nitrosonornicotine) and NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone)
NNN and NNK are among the most important of the so-called tobacco-specific nitrosamines. These compounds are formed in tobacco leaves from nitrite and amines (proteins). Thus, NNN and NNK are not added to tobacco, but are produced through a natural process.